Index Catalog // ScholarsArchive@OSU

Understanding polycyclic aromatic hydrocarbon (PAH) toxicity and inflammation in human bronchial epithelial cells

Creator:: Valdez, Teresa
Abstract:: There is increased emphasis on understanding cumulative risk from the combined effects of chemical and non-chemical stressors as it relates to public health. Recent animal studies have identified pulmonary inflammation as a possible modifier and risk factor for chemical toxicity in the lung after exposure to inhaled pollutants; however, little...
Resource Type:: Honors College Thesis
Full Text:: Susan C. Tilton There is increased emphasis on understanding cumulative risk from the combined

Impact of Polycyclic Aromatic Hydrocarbons on Barrier Function Toxicity in 3D Lung Model from Normal and Asthmatic Donor Cells

Creator:: Huynh, Celine T.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are known to cause adverse health effects in the human lung. Here, we evaluated biomarkers relevant for PAH toxicity in a 3D human primary bronchial epithelial cell (HBEC) model collected from normal and asthmatic donors. We previously found that PAHs decrease cellular barrier function integrity, which...
Resource Type:: Honors College Thesis
Full Text:: :_____________________________________________________ Susan C. Tilton Polycyclic aromatic hydrocarbons (PAHs) are known to cause adverse

Identifying microRNAs by automated phylogenetic and structural analysis

Creator:: Smith, Daniel P.
Abstract:: Motivation: It can take considerable amounts of time and effort to use existing computational tools to analyze a small RNA sequence for the purpose of determining if it is characteristic of microRNA. It is similarly tedious to search for homologs to known microRNA sequences in the rapidly growing collection of...
Resource Type:: Undergraduate Thesis
Full Text:: -navigate fashion. (a) (d) (c) (b) Figure 3. Selected pages of MiRPal’s web interface. (a

The Role of NhaP1, NhaP2, and NhaP3 Antiporters in the Acid Tolerance of Vibrio cholerae

Creator:: Gillon, Jacqueline and Schubiger, Carla
Abstract:: Vibrio cholerae (Vc), the etiological agent of cholera, has developed many mechanisms to combat the great fluctuations in pH, ion content and osmotic conditions of the vastly differing environments it encounters through its infections of the human host. A series of cation antiporters are found in the Vc membrane to...
Resource Type:: Undergraduate Thesis and Presentation

Addressing ALS: Corroborating the Methodology of Studying the P2X7R Complex

Creator:: Veytsman, Edward Y.
Abstract:: Amyotrophic lateral sclerosis (ALS) is characterized by the degeneration of motor neurons in the motor cortex and spinal cord. Recent evidence suggests that the purine receptor P2X7 (P2X7R) plays a central role in the pathology of ALS. Previous research indicates that P2X7R activation by oxidatively modified heat shock protein 90...
Resource Type:: Honors College Thesis
Full Text:: domain interacts with clients and co-chaperones (13). Lastly, the C-terminus interacts with the largest

Incorporation of aerodynamic and boundary layer resistances in determining initial evaporation rates of pesticides from turf grass

Creator:: Conway, Michael
Abstract:: Evaporative loss rates of pesticides, following application to turfgrass, were measured using the Backward-Time Lagrangian stochastic Dispersion model (Flesch, Wilson, Journal of Applied Meteorology, 34, pp. 1320-1332. All pesticides were applied to a 22.8 m x 22.8 m orchard ryegrass turf plot near Corvallis, Oregon. Solar radiation, ambient temperature, surface...
Resource Type:: Undergraduate Thesis

Metagenomics Analysis Reveal Host-Microbe Interactions in Cervical Cancer

Creator:: Lam, Khiem C.
Abstract:: Cervical cancer is the fourth most common cancer in women worldwide. Recently it has been shown that microbiota play a role in some types of cancer. Therefore, to understand whether microbes contribute in any way to the development and progress of cervical cancer, we investigated the cervical microbiome via analysis...
Resource Type:: Presentation and Honors College Thesis
Full Text:: F IG O S ta g e p g b a c t D N A /1 0 n g t o ta l * * * I I I I I I IV 0 .0 0

Immunohistochemistry Studies of Tumor Necrosis Factor Αlpha and Interferon Gamma Expression in Pseudocapillaria tomentosa Infected and Uninfected Zebrafish

Creator:: Lo, Lalee C.
Abstract:: Tumor necrosis factor alpha (TNF α) and interferon gamma (IFN γ) were initially recognized as inflammatory mediators produced by immune cells in response to infectious agents or foreign material. (1,5) However, over the past decade much research in mammalian species has indicated that these proteins also play key roles in...
Resource Type:: Presentation and Undergraduate Thesis
Full Text:: and Uninfected Zebrafish By Lalee C. Lo An Undergraduate Thesis Submitted to Oregon State

Generation of Kisspeptin Cell Lines to Investigate the Sex Steroid-Mediated Initiation of Puberty

Creator:: Jacobs, Dakota C.
Abstract:: Mammalian female reproduction requires preovulatory surges of gonadotropin-releasing hormone (GnRH) from neurons in the preoptic area (POA) of the hypothalamus, initiated by elevated estradiol (E₂). Rising E₂ activates a subset ofsexually dimorphic Kisspeptin neurons in the female, located in the anteroventralperiventricular nuclei (AVPV). Conversely, E₂ negative feedback is mediated by...
Resource Type:: Presentation and Undergraduate Thesis

Development of a colorimetric test kit to determine enzymatically produced pyruvic acid in sweet onions

Creator:: Merrill, Dawn C.
Abstract:: Sweet onions are valued for their unique flavor and praised for their health and dietary character. Onion sweetness is perceived as the degree of pungency decreases. Pungency can be quantitatively determined in onions by measuring enzymatically produced pyruvic acid. The onion industry quantifies a sweet onion as one having a...
Resource Type:: Undergraduate Thesis and Presentation

ScholarsArchive@OSU

Understanding polycyclic aromatic hydrocarbon (PAH) toxicity and inflammation in human bronchial epithelial cells

Impact of Polycyclic Aromatic Hydrocarbons on Barrier Function Toxicity in 3D Lung Model from Normal and Asthmatic Donor Cells

Identifying microRNAs by automated phylogenetic and structural analysis

The Role of NhaP1, NhaP2, and NhaP3 Antiporters in the Acid Tolerance of Vibrio cholerae

Addressing ALS: Corroborating the Methodology of Studying the P2X7R Complex

Incorporation of aerodynamic and boundary layer resistances in determining initial evaporation rates of pesticides from turf grass

Metagenomics Analysis Reveal Host-Microbe Interactions in Cervical Cancer

Immunohistochemistry Studies of Tumor Necrosis Factor Αlpha and Interferon Gamma Expression in Pseudocapillaria tomentosa Infected and Uninfected Zebrafish

Generation of Kisspeptin Cell Lines to Investigate the Sex Steroid-Mediated Initiation of Puberty

Development of a colorimetric test kit to determine enzymatically produced pyruvic acid in sweet onions

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