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Filtering by: Advisor Ingle, J. D. Remove constraint Advisor: Ingle, J. D. Degree Field Biochemistry and Biophysics Remove constraint Degree Field: Biochemistry and Biophysics

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  • Kinetic studies of the oxygen requirement of some amine oxidases

    Creator:
    Swindell, Robert Malcolm
    Abstract:
    Some kinetics of the oxygen requirement of amine oxidases have been investigated using bovine plasma monoamine oxidase (PAO) and pea seedling diamine oxidase (DAO). A system is described for studying enzyme reactions under controlled oxygen tension and in an O₂-free N₂ atmosphere. O₂ Km values were determined at two different...
    Resource Type:
    Masters Thesis
    Full Text:
    . D. J. Reed Some kinetics of the oxygen requirement of amine oxidases have been investigated

  • Specific enzymic interactions relating to the mechanism of action on certain 2-chloroethyl nitrosoureas

    Creator:
    Babson, John Robert
    Abstract:
    Certain 2- chioroethyl nitrosoureas have been demonstrated to be highly specific inactivators of chymotrypsin in vitro and glutathione reductase, both in vivo and in isolated rat hepatocytes. The inactivation of glutathione reductase in isolated hepatocytes resulted in an increased sensitivity toward an adriamycin induced oxidative challenge. Prolonged incubation of 1-(2-chloroethyl)-3-([1-¹⁴...
    Resource Type:
    Dissertation
    Full Text:
    Abstract approved: Redacted for Privacy U. J. Keea Certain 2- chioroethyl nitrosoureas have been demon