Index Catalog // ScholarsArchive@OSU

Base inclinations in natural and synthetic DNAs

Creator:: Chou, Ping-Jung
Abstract:: A sophisticated computer program is developed to analyze flow linear dichroism data on nucleic acids for individual base inclinations. Measured absorption and linear dichroism data for synthetic AT and GC polymers and natural DNAs are analyzed. The reliability of the program is tested on data for the synthetic polymers, and...
Resource Type:: Dissertation
Full Text:: Approved: Dr. W. Curtis Jo son, Jr. A sophisticated computer program is developed to analyze flow linear

Base inclinations for DNA in solutions and films as revealed by linear dichroism

Creator:: Kang, Hunseung
Resource Type:: Dissertation
Full Text:: in Solutions and Films as Revealed by Linear Dichroism. Abstract Approved by : Dr. W. Curtis

Stabilization of Z-DNA by demethylation of thymine bases : a crystallization and thermo-dynamic study of d(m⁵CGUAm⁵CG)

Creator:: Zhou, Guangwen
Resource Type:: Dissertation
Full Text:: extend to my other graduate committee members, Dr. Douglas Keszler, Dr. W. Curtis Johnson, Dr. Ching Yuan

Voluntary alcohol consumption in male rhesus macaques suppresses cancellous bone remodeling

Creator:: Kahler-Quesada, Arianna M.
Abstract:: Background: Chronic heavy alcohol consumption is a risk factor for bone fracture. Using a non-human primate model of voluntary alcohol self-administration, we have recently shown that alcohol consumption suppresses intracortical bone remodeling. The current study extends this investigation to asses the effect of alcohol consumption on cancellous bone mass, architecture,...
Resource Type:: Honors College Thesis
Full Text:: ) voluntarily self-administered water or alcohol (4% w/v) for 22h/d, 7d/wk for a total of 12 months. Control

An electrophoretic investigation of nucleoprotein organization in yeast chromatin

Creator:: Szent-Györgyi, Christopher Stephan
Abstract:: I have investigated nucleoprotein organization in chromatin of the yeast, Saccharomyces cerevisiae. My approach has been to prepare insoluble, minimally per turbed chromatin from a mitochondrial DNA-free strain of yeast, using a number of new techniques, and then digest this substrate with micrococcal nuclease. The soluble products are electrophoresed on...
Resource Type:: Dissertation
Full Text:: 10% ammonium persulfate (w/v) f TEMEDg 0.75 0.15 STACKING GELS 10 X stacking buffers 10. 50

Metabolic pathway of the nitrosoureas catalyzed by cytochrome P-450 and NADPH cytochrome P-450 reductase

Creator:: Potter, David Willard
Abstract:: Three highly purified forms of cytochrome P-450 (P-450a, P-450b, P-450c) from Aroclor 1254-induced rat hepatic microsomes catalyzed the monooxygenation of 1-(2- chloroethyl)-3-(trans-4-methylcyclohexyl)-1-nitrosourea (MeCCNU) and 1-(2-chloroethyl)-3-(cyclohexyl)-1-nitrosourea (CCNU) in the presence of purified NADPH cytochrome P-450 reductase, NADPH and oxygen. Cytochrome P -450- dependent monooxygenation of CCNU gave six alicyclic hydroxylation products...
Resource Type:: Dissertation
Full Text:: AND LIPID CONCENTRATION ON RATES OF MONOOXYGENATION 120 a 100 w 1-17 80 0 co .(t 60 w 2 40 2 20

Structure and function of chromatin : studies at the nucleosome and nuclear matrix levels

Creator:: Shih, Ah Shing
Abstract:: Several levels of eukaryotic chromatin structure have been observed: the nucleosome, the 10 nm and 30 nm fibers and loop domains, apparently attached to the nuclear matrix. In this research, the structure and function of chromatin at two of these levels was investigated, with studies on both nucleosome positioning and...
Resource Type:: Dissertation
Full Text:: . Gary F. Merrill, Dr. Henry W. Shaup, Dr. George D. Pearson, Dr. David W. Barnes, Dr. George S. Bailey

On the location of the linker histones and the linker DNA in the 30 nm fiber of chromatin

Creator:: Leuba, Sanford H.
Abstract:: Understanding the structure of the 30 nm fiber in chromatin is relevant to understanding eukaryotic replication and transcription. The major controversy among the models of the fiber concerns the disposition of the linker DNA, the DNA between adjacent nucleosomes, and the location of the linker histones. To determine if the...
Resource Type:: Dissertation
Full Text:: . Cells wash w/ buffer containing Triton X-100 break cell membranes sPin wash out the triton sPin wash

Biological activity of avian myeloblastosis virus RNA in cell-free systems for protein synthesis

Creator:: Olson, Kenneth Charles
Abstract:: Avian myeloblastosis virus RNA was fractionated into a high molecular weight RNA and a low molecular weight RNA fraction by sucrose density centrifugation. The larger RNA component had a sedimentation constant of 65S and the low molecular weight RNA about 4S. The low molecular RNA has two biological properties of...
Resource Type:: Masters Thesis
Full Text:: thanks for this is due Dr. George S. Beaudreau, Dr. Anne Deeney and John W. Carnegie. Special thanks

Effects of nucleosomes on transcription by polymerase I in a reconstituted system

Creator:: Georgel, Philippe, 1961-
Abstract:: The aim of this study was to gain more information about the interactions between DNA and the histone octamer during the process of transcription. This work used a pUC8 plasmid derivative that contained the core promoter region of the RNA polymerase I of Acanthamoeba castellanii, placed upstream of four repeats...
Resource Type:: Dissertation
Full Text:: solution of polyglutamic acid at a PGA:histone ratio of 2:1 (w/w). The relaxed plasmid was then added to

ScholarsArchive@OSU

Base inclinations in natural and synthetic DNAs

Base inclinations for DNA in solutions and films as revealed by linear dichroism

Stabilization of Z-DNA by demethylation of thymine bases : a crystallization and thermo-dynamic study of d(m⁵CGUAm⁵CG)

Voluntary alcohol consumption in male rhesus macaques suppresses cancellous bone remodeling

An electrophoretic investigation of nucleoprotein organization in yeast chromatin

Metabolic pathway of the nitrosoureas catalyzed by cytochrome P-450 and NADPH cytochrome P-450 reductase

Structure and function of chromatin : studies at the nucleosome and nuclear matrix levels

On the location of the linker histones and the linker DNA in the 30 nm fiber of chromatin

Biological activity of avian myeloblastosis virus RNA in cell-free systems for protein synthesis

Effects of nucleosomes on transcription by polymerase I in a reconstituted system

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