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Filtering by: Creator Sun, Mindy Degree Field Biochemistry and Biophysics

Understanding Circadian and Light-activated Transcriptional Regulatory Changes During Aging in Drosophila melanogaster

Creator:

Fey, Rosalyn M.

Abstract:

Systems biology is a powerful approach which considers and sheds light on all of the puzzle pieces which make up complex biological processes, and is an effective alternative to unraveling these processes using traditional molecular approaches alone. It is a natural companion approach for computational biology, which leverages the power...

Resource Type:

Dissertation
DNA binding and beyond : an investigation of proteins involved in PAH-induced carcinogesesis

Creator:

Hooven, Louisa Ada

Abstract:

Exposure to polycyclic aromatic hydrocarbons such as benzo[a]pyrene (B[a]P) has been determined to be a risk factor for various forms of human cancer. PAH DNA adducts have been shown to cause mutations, but carcinogenesis is also accompanied by alterations in gene expression. Inhibiting individual cytochrome P450s could clarify the interaction...

Resource Type:

Dissertation