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Filtering by: Creator Jackson, Eric Degree Field Bioengineering

Engineering an Ex-Vivo System to Study Transport Phenomena in the Human Intervertebral Disc

Creator:

Shalash, Ward

Abstract:

Back pain is the leading cause of disability worldwide, entailing a significant socioeconomic impact. A primary source of back pain can be attributed to intervertebral disc (IVD) degeneration allowing nerve ingrowth, facet joint arthritis, disc bulging, and osteophyte formations that press on nearby nerve roots or the spinal cord. While...

Resource Type:

Dissertation

Full Text:

and Urban 2004; Jackson et al. 2009). Loss of viable cells in the IVD leads to the deterioration of
Entrapment of Micro-Algae in Modified Alginate Beads for Oxygen and Nutrient Source

Creator:

Hughson, Jason D.

Abstract:

Presented here is an investigation and comparison of two entrapment methods of algae. Conventional calcium alginate bead entrapment is compared to a recently described modified bead entrapment method, utilizing poly(ethylene glycol) and calcium alginate, which results in void or capillary formation within the beads. It is shown that algal growth...

Resource Type:

Honors College Thesis

Full Text:

was ASM-1 (modified), both obtained from Eric Henry, PhD (Department of Botany and Plant Pathology
Precision Medicine for the Intervertebral Disc: Image Processing and Computational Modeling of Disc Degeneration to Inform Patient-Specific Therapies

Creator:

Ahrens, Sonia R.

Abstract:

The human intervertebral disc is a deceptively simple structure which plays an essential role in human movement. Even slight changes to the disc microenvironment can have far reaching consequences, particularly when these changes result in disc degeneration and herniation. Degeneration is increasingly tied to lower back pain; better understanding this...

Resource Type:

Masters Thesis

Full Text:

Alicia R. Jackson,63 among others64–66. These groups have each characterized key properties related to