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Quantitative 3D Image Analysis of a Zebrafish Xenograft Model of Glioblastoma Cell Proliferation

Creator:: Kang, Christine
Abstract:: Glioblastoma multiforme is the most common primary brain tumor in adults ages 45-70, with over 12,120 new cases in the U.S. predicted for 2016 alone. Glioblastoma is also one of the most difficult cancers to treat because the tumor cells tend to invade into the surrounding healthy tissue, making it...
Resource Type:: Honors College Thesis
Full Text:: vertebrate anatomy, lack of an adaptive immune system for the first 4-6 weeks, as well as a dense

Quantitative 3D Image Analysis of a Zebrafish Xenograft Model of Glioblastoma Cell Proliferation

Creator:: Kang, Christine
Abstract:: Glioblastoma multiforme is the most common primary brain tumor in adults ages 45-70, with over 12,120 new cases in the U.S. predicted for 2016 alone. Glioblastoma is also one of the most difficult cancers to treat because the tumor cells tend to invade into the surrounding healthy tissue, making it...
Resource Type:: Honors College Thesis
Full Text:: of an adaptive immune system for the first 4-6 weeks, as well as a dense microenvironment

Effect of Polyethylene Oxide (PEO) Modification on the Structure and Antimicrobial Activity of the Antimicrobial Peptide WLBU2

Creator:: Raper, Miranda A.
Abstract:: Sepsis is a blood infection that is caused by circulating bacteria cells and cell fragments, which contain immunogenic lipopolysaccharides (LPS) or endotoxin. The circulating endotoxin results in a severe dysregulation of the inflammatory response that ultimately leads to organ failure. One promising treatment method is removal of endotoxin by passing...
Resource Type:: Honors College Thesis
Full Text:: broth and LB broth with E. coli cells were each added to 3 wells of a clear, 96-well microplate in a

Quantification of fibrinogen adsorption to nisin-loaded polyethylene oxide layers

Creator:: Auxier, Julie A.
Abstract:: Antimicrobial coatings used to reduce the risk of infection caused by tissue-contacting medical devices must address specific biocompatibility requirements including prevention of thrombosis and rise of bacterial resistance. An antimicrobial-loaded poly(ethylene-oxide) (PEO) coating has been tentatively shown to be non-fouling with sustained antimicrobial activity. However, the presence of the antimicrobial,...
Resource Type:: Honors College Thesis
Full Text:: ELISA (Figure 7). A primary antibody is first adhered to the bottom of a well

Multiple Approaches to Novel Rifamycin Analogs to Combat MDR-TB

Creator:: Blank, Jessica A.
Abstract:: According to the Center for Disease Control and Prevention (CDC), in 2015 10.4 million people worldwide became infected with tuberculosis (TB) with 1.8 million TB related deaths. Tuberculosis is a bacterial infectious disease caused by Mycobacterium tuberculosis, a slow growing yet highly infectious bacterium. Among the first line of treatments...
Resource Type:: Honors College Thesis
Full Text:: Tuberculosis (TB) is a well known and often thought of disease within the landscape of global medicine and

Biomimetic synthesis of GeO₂ and TiO₂ utilizing the R5 and poly-l-lysine peptides

Creator:: Helman, Talia A., Gessford, Makayla, and Baio, Joe
Abstract:: Diatoms, the most common type of algae, are one of the most prevalent organisms in the world. They live in wet ambient environments such as oceans, lakes and rivers and are easily recognizable because of their unique structure. Diatoms are surrounded by a silica cell wall called a frustule. The...
Resource Type:: Poster
Full Text:: Powerpoint template for a scientific poster

Rational Design of Ex Vivo Model of Thrombosis

Creator:: Patel, Ishan A., Berny-Lang, Michelle A., Tormoen, Garth W., White-Adams, Tara C., Tucker, Erik I., Baker, Sandra M., Gruber, Andras, and McCarty, Owen J. T.
Abstract:: Occlusive thrombi that cause cardiovascular diseases form on the walls of blood vessels and propagate across the lumen under pressure gradient-driven flow, impaired antithrombotic, and enhanced prothrombotic conditions. Development of a well controlled and validated ex vivo model that can mimic these pathological conditions would provide a useful tool for...
Resource Type:: Poster

Investigating the Hemocompatibility of Blood-Contacting Biomaterials

Creator:: Hummel, Madeleine H.
Abstract:: Surface-associated thrombosis is a critical concern in medical device development. Current extracorporeal circulation units require systemic anticoagulation to avoid thrombosis, which can cause adverse effects such as thrombocytopenia, hypertriglyceridemia, and hyperkalemia. To address this issue, we combine the technology of polydopamine (PDA) functionalization with slippery liquid infused porous surfaces (SLIPS)....
Resource Type:: Masters Thesis
Full Text:: . To perform a colorimetric assay for FXII, first the wells of a non-treated polystyrene 96-well

SIMstat: Hardware Design Considerations for Implementing a Low-Cost, Portable Potentiostat

Creator:: Cook, Jacob M.
Abstract:: Electroanalytical techniques allow scientists and engineers to characterize bulk solutions as well as interfaces. Potentiostats are commonly used by researchers in a variety of disciplines to analyze the chemistry which occurs at a working electrode surface. Advancements in microelectronics and the proliferation of open-source designs have allowed researchers to construct...
Resource Type:: Honors College Thesis
Full Text:: interfacing as well as a suggested testing/validation process will be highlighted. 3 2

Correlation of NE 1545 expression and cell size in Nitrosomonas europaea exposed to a suite of aromatic hydrocarbons

Creator:: Gilroy, Caslin Anne
Abstract:: Ammonia oxidizing bacteria, including Nitrosomonas europaea, are inhibited by aromatic hydrocarbons which can be found in wastewater treatment plants. In recent studies, changes have been observed in N. europaea cell size upon exposure to benzene, but not toluene. Additionally, NE 1545, a gene proposed to be involved in fatty acid...
Resource Type:: Honors College Thesis
Full Text:: Ammonia-oxidizing bacteria (AOB) are a group of bacteria that

ScholarsArchive@OSU

Quantitative 3D Image Analysis of a Zebrafish Xenograft Model of Glioblastoma Cell Proliferation

Quantitative 3D Image Analysis of a Zebrafish Xenograft Model of Glioblastoma Cell Proliferation

Effect of Polyethylene Oxide (PEO) Modification on the Structure and Antimicrobial Activity of the Antimicrobial Peptide WLBU2

Quantification of fibrinogen adsorption to nisin-loaded polyethylene oxide layers

Multiple Approaches to Novel Rifamycin Analogs to Combat MDR-TB

Biomimetic synthesis of GeO₂ and TiO₂ utilizing the R5 and poly-l-lysine peptides

Rational Design of Ex Vivo Model of Thrombosis

Investigating the Hemocompatibility of Blood-Contacting Biomaterials

SIMstat: Hardware Design Considerations for Implementing a Low-Cost, Portable Potentiostat

Correlation of NE 1545 expression and cell size in Nitrosomonas europaea exposed to a suite of aromatic hydrocarbons

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