Index Catalog // ScholarsArchive@OSU

Effects of small molecule ligands on the conformational dynamics of the Farnesoid X Receptor ligand binding domain (FXR-LBD)

Creator:: Yang, Liping
Abstract:: The Farnesoid X Receptor (FXR) is a member of the nuclear receptor superfamily of transcription factors that plays a key role in the regulation of bile acids, lipid and glucose metabolisms. The regulative function of FXR is governed by conformational changes of the ligand binding domain (LBD) upon ligand binding....
Resource Type:: Dissertation

Isolation and identification of certain toxic compounds in a fraction of Kraft mill waste

Creator:: Wiman, Robert Edgar, 1933-
Resource Type:: Dissertation
Full Text:: the procedure of Martin (11) for 22 hours. At that time, the toluene layer was separated and ex

Photochemistry of 6-alkenyl-2-cyclohexenones : synthetic studies towards precursors of ryanodol

Creator:: Wang, Bingbing
Abstract:: Regiochemistry of intramolecular [2+2] photocycloadditions of oxygenated 6-alkenyl-3-alkoxy-2-cyclohexenones is studied. Application of this methodology to construct a key intermediate [3.3.2] bicyclic skeleton of ryanodol is described as well. Irradiation of (3-butenyl)compounds 3, 11, 14 and of (4-pentenyl)compound 6 afforded exclusively the linear photoadducts 4, 12, 15 and 7 respectively. Irradiation...
Resource Type:: Masters Thesis
Full Text:: , Chanokporn Phaosiri, Mari Martin, Kristin Ziebar for their friendship. To the past and present members of

Investigating Low-Frequency Vibrations in Condensed Matter Using Time-Resolved Third-Harmonic Generation Spectroscopy

Creator:: Wang, Liang
Abstract:: In this thesis, I present a new method we developed to study low frequency (< 700 cm⁻¹) vibrational dynamics: Time-resolved third-harmonic generation (TRTHG) spectroscopy. Among a variety of vibrational spectroscopy techniques, TRTHG differentiates itself with robustness, versatility, and simplicity. In TRTHG experiment, that involves only two ultrashort laser pulses, the...
Resource Type:: Masters Thesis

Synthesis and study of oxides and chalcogenides : thin films and crystals

Creator:: Park, Sangmoon
Abstract:: Several types of solid-state inorganic materials are prepared and characterized. By using the SILAR (Successive Ionic Layer Adsorption and Reaction) deposition method in conjunction with hydrothermal dehydration both low-temperature deposition and crystallization of oxide thin films are achieved. Various aspects of new transparent p-type materials are studied by examining both...
Resource Type:: Dissertation

Total Synthesis of Tryptamine Alkaloids from the Arundo and Leuconotis Genera

Creator:: Ferreira, Andrew
Abstract:: The first part of this manuscript is about the total synthesis of the Arundo donax bis(indole) natural products. The A. donax alkaloids were prepared using the first example of an ynindole Diels–Alder reaction. Each were then separated, isolated, and determined to have stable enantiomeric conformations at room temperature (Chen, J.;...
Resource Type:: Dissertation

On the Properties and Characteristics of Solution Processed Hafnium Based Thin-Films from Aqueous Precursors

Creator:: Decker, Shawn R.
Abstract:: Aqueous hydroxo Hf nanoclusters enable studies to identify and codify steps in the deposition of Hf-based oxide thin films from solution precursors. HfOCl2 reacts with combinations of H2O2(aq), acids, and TMAH to produce polymetal species at high pH and low pH. X-ray scattering and spectroscopic methods reveal the nature of...
Resource Type:: Dissertation

Mechanisms of internal substitution reactions

Creator:: Engebrecht, Ronald Henry
Resource Type:: Dissertation
Full Text:: Thiolsulfonate Decomposition. The observations by Martin (51, p. 1561; 52) that substituents and solvent

Synthesis and characterization of aluminum oxide based materials - from molecule to device

Creator:: Wang, Wei
Abstract:: A scalable synthesis of the "flat" tridecameric inorganic cluster [Al₁₃(μ₃-OH)₆(μ-OH)₁₈(H₂O)₂₄]¹⁵⁺ has been realized by treating an aqueous aluminum nitrate solution with zinc-metal powder at room temperature. Single crystals and polycrystalline samples are readily obtained in yields exceeding 55% relative to the starting reagent Al(NO₃)₃. Products have been characterized by X-ray...
Resource Type:: Dissertation

Studying fusion reactions for effect of PCN on heavy nucleus formation and for nuclear structure effects

Creator:: Naik, Radhika
Abstract:: The fusion reaction ²⁰⁸Pb (⁵⁰Ti, xn) ²⁵⁸⁻x Rf (x = 1-3) was studied to determine PCN (probability that the mononucleus system evolves to form a compound nucleus inside the fission saddle point) and to establish the value of Wsur (survival probability) for the given reaction experimentally. The fission excitation function...
Resource Type:: Dissertation

ScholarsArchive@OSU

Effects of small molecule ligands on the conformational dynamics of the Farnesoid X Receptor ligand binding domain (FXR-LBD)

Isolation and identification of certain toxic compounds in a fraction of Kraft mill waste

Photochemistry of 6-alkenyl-2-cyclohexenones : synthetic studies towards precursors of ryanodol

Investigating Low-Frequency Vibrations in Condensed Matter Using Time-Resolved Third-Harmonic Generation Spectroscopy

Synthesis and study of oxides and chalcogenides : thin films and crystals

Total Synthesis of Tryptamine Alkaloids from the Arundo and Leuconotis Genera

On the Properties and Characteristics of Solution Processed Hafnium Based Thin-Films from Aqueous Precursors

Mechanisms of internal substitution reactions

Synthesis and characterization of aluminum oxide based materials - from molecule to device

Studying fusion reactions for effect of PCN on heavy nucleus formation and for nuclear structure effects

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