Index Catalog // ScholarsArchive@OSU

Displacement-based fluorescent microRNA biosensors : design principles and analytical metrics

Creator:: Larkey, Nicholas E.
Abstract:: One post-transcriptional mechanism that regulates the progression of cancer and other diseases involves small 22-23 nucleotide sequences called microRNA (miR). Early detection of small changes in concentration of these biomarkers holds potential to diagnose diseases at their earliest stages. Use of current nucleic-acid based biosensors, like molecular beacons, for in...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Nicholas E

Synthetic studies of nonadrides

Creator:: Drapela, Nicholas Ernest
Abstract:: An asymmetric approach to the synthesis of byssochlamic acid (1) is described. Regioisomeric enzymatic differentiation is described in the selective hydrolysis of dimethyl ester 30 by porcine liver esterase. Chiral dimethyl ester 42 was prepared by desymmetrization of cyclopentene 34 using porcine liver esterase. A key intramolecular [2+2]cycloaddition-cycloreversion photometathesis of...
Resource Type:: Dissertation
Full Text:: by Nicholas Ernest Drape la A DISSERTATION submitted to Oregon State University in partial

Adsorption properties of virgin and irradiated graphite

Creator:: Spalaris, Constantine Nicholas
Resource Type:: Dissertation
Full Text:: ADSORPTION PROPERTIES OF VIRGIN AND IRRADIATED GRAPHITE by CONSTANTINE NICHOLAS SPALARIS A THESIS

Addition of substituted phenylthiyl radicals to substituted α-methylstyrenes

Creator:: Geers, Brian Nicholas
Resource Type:: Masters Thesis
Full Text:: Brian Nicholas Geers A THESIS submitted to Oregon State University in partial fulfillment of the

Per- and Polyfluoroalkyl Substances (PFASs) and Aqueous Film-Forming Foam Impacted Sites : New PFAS Discovery and Sorption of Anionic, Zwitterionic, and Cationic PFASs

Creator:: Barzen-Hanson, Krista A.
Abstract:: Public attention and concern about per- and polyfluoroalkyl substances (PFASs) are increasing due to detection of PFASs in drinking water supplies, the environment, including remote locations, and wildlife and to the lowering of the federal health advisory levels of perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) in drinking water. Aqueous film-forming...
Resource Type:: Dissertation
Full Text:: Krista A. Barzen-Hanson for the degree of Doctor of Philosophy in Chemistry presented on January 10

Exploratory Studies Within the Exotic Lyonsite Structure

Creator:: Tang, Joseph N.
Abstract:: Structure-property relationships have always underpinned the field of solid state chemistry; dependable structural descriptions are integral to understanding and controlling the physical properties of inorganic compounds old and new. While a handful of crystal structures are celebrated for their versatility, flexibility, and functionality, the existence of more exotic structures is...
Resource Type:: Dissertation
Full Text:: Studies Within the Exotic Lyonsite Structure Abstract approved: Munirpallam A. Subramanian Structure

Natural and semi-synthetic compounds with biocidal activity against arthropods of public health importance

Creator:: Khasawneh, Mohammad A.
Abstract:: This study identified new compounds with pest control activities. The two sources of candidates that were followed here were the main heartwood extract of Alaska Yellow Cedar (AYC) constituents and several semi-synthetic counterparts. Five compounds were isolated and identified for the first time in AYC heartwood in this research: two...
Resource Type:: Dissertation
Full Text:: AN ABSTRACT OF THE DISSERTATION OF Mohammad A. Khasawneh for

Gene Activation Strategies in Filamentous Fungi for Natural Products Discovery

Creator:: Adpressa, Donovon A.
Abstract:: Fungi have long been a prolific source of clinically approved drugs. The antibiotic penicillin, the cholesterol lowering statins, and the immunosuppressant cyclosporine have changed the treatment of human diseases in the last century. Recently, genome analysis of filamentous fungi has revealed that the biosynthetic potential for natural product expression is...
Resource Type:: Dissertation
Full Text:: : _____________________________________________________________________ Sandra Loesgen Fungi have long been a prolific source of clinically approved drugs. The

Reaction Pathways of Oxo-Hydroxo Group 5 Clusters to Metal Oxide Thin Films

Creator:: Mansergh, Ryan H.
Abstract:: Oxo-hydroxo Group 5 metal clusters are an untapped resource to study and advance aqueous solution processing of metal oxide thin films. The tetramethylammonium (TMA) hexatantalate salt (TMA6[H2Ta6O19]) yields dense Ta2O5 films (~95% of the bulk ß-Ta2O5 density) with atomically smooth surfaces (<4 Å root mean square surface roughness). This same...
Resource Type:: Dissertation
Full Text:: . Abstract approved: _____________________________________________________ Douglas A. Keszler Brady J

Purification of 2,5-dihydroxyacetanilide epoxidase and mechanism of hydroquinone epoxidases

Creator:: Kirchmeier, Marc J.
Abstract:: 2,5-dihydroxyacetanilide epoxidase from Streptomyces LL-C10037 (DHAE I) catalyzes the epoxidation of hydroquinone 4, to form epoxyquinone 7. DHAE I has been purified to homogeneity, with an overall purification factor greater than 23,000. N-terminal and internal amino acid sequences have been obtained from the purified enzyme so that the epoxidase gene...
Resource Type:: Dissertation
Full Text:: elucidated using isotopically labeled oxygen. DHAE I is a dioxygenase belonging to a new and unrecognized

ScholarsArchive@OSU

Displacement-based fluorescent microRNA biosensors : design principles and analytical metrics

Synthetic studies of nonadrides

Adsorption properties of virgin and irradiated graphite

Addition of substituted phenylthiyl radicals to substituted α-methylstyrenes

Per- and Polyfluoroalkyl Substances (PFASs) and Aqueous Film-Forming Foam Impacted Sites : New PFAS Discovery and Sorption of Anionic, Zwitterionic, and Cationic PFASs

Exploratory Studies Within the Exotic Lyonsite Structure

Natural and semi-synthetic compounds with biocidal activity against arthropods of public health importance

Gene Activation Strategies in Filamentous Fungi for Natural Products Discovery

Reaction Pathways of Oxo-Hydroxo Group 5 Clusters to Metal Oxide Thin Films

Purification of 2,5-dihydroxyacetanilide epoxidase and mechanism of hydroquinone epoxidases

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