Index Catalog // ScholarsArchive@OSU

Using the Microbial Tree of Life to Describe Mammalian Health and Disease

Creator:: Arnold, Holly Kristin
Abstract:: The past decade of research has potentiated a revolution in our understanding of mammalian health and evolution by revealing that the gut microbiome plays a central role in mammalian physiology. Our ability to unlock this potential hinges upon the identification of specific groups of gut microbes that elicit effects on...
Resource Type:: Dissertation
Full Text:: gastrointestinal tract, such as infectious disease diagnostics37,38, intestinal cancer screening37,39,40

Proteomic Profiles of Circulating Exosomes as Biomarkers for Disease Detection in Canine Osteosarcoma

Creator:: Brady, Jacqueline V.
Abstract:: Osteosarcoma (OSA) is the most common primary skeletal tumor in dogs accounting for 85% of bone tumors and nearly 6% of all canine neoplasms. They are highly aggressive tumors that carry a poor prognosis despite intensive treatment, highlighting the need for more effective diagnostic and therapeutic tools. Recent research in...
Resource Type:: Masters Thesis
Full Text:: for Disease Detection in Canine Osteosarcoma Abstract approved

Aspects of the parasite fauna and related diseases in juvenile fishes in Upper Klamath Lake, OR

Creator:: Janik, Andrew J.
Abstract:: Shortnose Sucker (Chasimistes brevirostris) and Lost River Sucker (Deltistes luxatus) are endemic to the Upper Klamath Basin of Southern Oregon and Northern California. Populations of these fishes have been dwindling since the 1960’s and both species where listed to as endangered in 1988. Poor recruitment is thought to be a...
Resource Type:: Masters Thesis
Full Text:: Sciences presented on December 8, 2017. Title: Aspects of the Parasite Fauna and Related Diseases in

Inclusion Fusion and Genetic Recombination: Bridging the Gap Between the Chlamydiae

Creator:: Garvin, Lotisha E.
Abstract:: Chlamydia is an obligate intracellular bacterial pathogen that causes a variety of disease in animals and humans worldwide. Veterinary chlamydial pathogens can lead to chronic infections and serious consequences that result in millions of dollars of losses in animals and resources in the agricultural industry in countries that rear ruminants....
Resource Type:: Dissertation
Full Text:: Chlamydia is an obligate intracellular bacterial pathogen that causes a variety of disease in animals and

Bacterial and Host Factors Contributing to Mycobacterium avium subspecies paratuberculosis Persistent Infection

Creator:: Phillips, Ida L.
Abstract:: Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s disease, a chronic granulomatous enteritis that plagues domestic and wild ruminants globally. During the silent stages of Johne’s disease, infected animals intermittently shed bacteria for years prior to clinical diagnosis during advanced disease stages. This strategy allows MAP to...
Resource Type:: Dissertation
Full Text:: Johne’s disease are predisposed to other conditions for which they are commonly culled. These diseases

Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

Creator:: Nagamine, Brandy S.
Abstract:: The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...
Resource Type:: Dissertation
Full Text:: and the prevention of disease, a fact already established. As pathogens continuously evolve more

Pseudoloma neurophilia in the Zebrafish (Danio rerio) : Consequences of Infection on Neurobehavioral and Biomedical Research using a Burgeoning Model Organism

Creator:: Spagnoli, Sean
Abstract:: Since its inception as a laboratory animal in the early 1970s, the zebrafish has proven itself a rising star in the world of comparative biomedical sciences due to its short generation time, ease of care, external fertilization, and transparent larvae. In a very few decades, the zebrafish has been utilized...
Resource Type:: Dissertation
Full Text:: for biosecurity and elimination of infectious disease was not viewed as particularly important

The Signaling Role of Divalent Cations in Clostridium perfringens Spore Germination

Creator:: Almatrafi, Roua
Abstract:: Clostridium perfringens is an anaerobic, gram-positive, rod-shaped, spore-forming bacterium that leads to a broad range of diseases in humans and animals [23, 27, 50]. Among seven C. perfringens types (type A-G), type F is known to be the most common bacteria that is responsible for causing human food-borne disease outbreaks...
Resource Type:: Masters Thesis
Full Text:: - forming bacterium that leads to a broad range of diseases in humans and animals [23, 27, 50]. Among

Inhibition of Clostridium perfringens spore growth by synergistic effects of different antimicrobials

Creator:: Alhabeeb, Rabiaa
Abstract:: Clostridium perfringens is a spore-forming anaerobic organism that is commonly present in fresh meat and poultry. The organism's spores can survive a range of food processing methods. C. perfringens type F isolates are the causative agents of C. perfringens type F food poisoning (FP) and non-food borne (NFB) human gastrointestinal...
Resource Type:: Masters Thesis
Full Text:: and nonfood-borne human gastrointestinal diseases. The enterotoxin gene (cpe) can be found on the

The immunomodulatory role of canine mesenchymal stem cell-derived extracellular vesicles

Creator:: Phelps, Shannon M.
Abstract:: Immune-mediated diseases are a frequent cause of morbidity and mortality in canine patients. Treatments currently involve generalized suppression of the immune system, and corticosteroids are often used as a first-line agent. While often effective, corticosteroids are unlikely to induce remission without substantial side effects. Second-line immunosuppressive agents may be effective...
Resource Type:: Masters Thesis
Full Text:: immune-mediated disease Immune-mediated diseases are a common cause of morbidity and mortality in

ScholarsArchive@OSU

Using the Microbial Tree of Life to Describe Mammalian Health and Disease

Proteomic Profiles of Circulating Exosomes as Biomarkers for Disease Detection in Canine Osteosarcoma

Aspects of the parasite fauna and related diseases in juvenile fishes in Upper Klamath Lake, OR

Inclusion Fusion and Genetic Recombination: Bridging the Gap Between the Chlamydiae

Bacterial and Host Factors Contributing to Mycobacterium avium subspecies paratuberculosis Persistent Infection

Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

Pseudoloma neurophilia in the Zebrafish (Danio rerio) : Consequences of Infection on Neurobehavioral and Biomedical Research using a Burgeoning Model Organism

The Signaling Role of Divalent Cations in Clostridium perfringens Spore Germination

Inhibition of Clostridium perfringens spore growth by synergistic effects of different antimicrobials

The immunomodulatory role of canine mesenchymal stem cell-derived extracellular vesicles

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