Index Catalog // ScholarsArchive@OSU

Characterization of Membrane Vesicles Released by the Opportunistic Human Pathogen Mycobacterium avium subsp. hominissuis (MAH) in Response to an in vitro System Mimicking the Phagosomal Environment

Creator:: Chiplunkar, Sanket S.
Abstract:: Mycobacterium avium subsp. hominissuis (MAH) belongs to the most-clinically significant non-tuberculous mycobacterial (NTM) pathogens with constant increase in disease prevalence, mainly in several industrialized western countries where tuberculosis is less prevalent. Upon entry into the alveolar space, MAH is engulfed by resident-macrophages, where the pathogen adapts to the hostile phagosomal...
Resource Type:: Masters Thesis
Full Text:: and catalase (OADC, Hardy Diagnostics, Santa Maria, CA) at 37º C, until mid-log phase (which is 7-8

Cannabidiol Effects on NMDA and AMPA Receptor Activity and Cognitive Function at a High Dose in 5xFAD Mice

Creator:: Sackinger, Emily P.
Abstract:: Alzheimer’s Disease (AD) is an abnormal part of aging that mainly affects those over the age of 65. The current therapies are only FDA approved for mild to moderate AD symptoms. Cannabidiol (CBD) is a non-intoxicating constituent of Cannabis sativa that has been shown to have beneficial effects on cancer,...
Resource Type:: Masters Thesis
Full Text:: Stellos, 2020), which is a protein required for neurodevelopment and neuronal growth (M. del C

Molecular Signaling Patterns of the Articular Cartilage and Marginal Transition Zone in Foals with Osteochondrosis

Creator:: Marchant, Liz
Abstract:: Osteochondrosis (OC) is a developmental orthopedic disease that results from a disruption to normal endochondral ossification in the articular-epiphyseal growth complex. In mammals, the hedgehog pathway and growth factor signaling are essential to this process. Previous studies in yearling horses with OC have shown upregulation of Indian hedgehog and insulin-like...
Resource Type:: Masters Thesis
Full Text:: monoclonal (MMP-3, MMP-13, Dkk-1, Wnt 4, Sox9, Collagen type IIB, Osteocalcin, Cytochrome C). Our

Using the Microbial Tree of Life to Describe Mammalian Health and Disease

Creator:: Arnold, Holly Kristin
Abstract:: The past decade of research has potentiated a revolution in our understanding of mammalian health and evolution by revealing that the gut microbiome plays a central role in mammalian physiology. Our ability to unlock this potential hinges upon the identification of specific groups of gut microbes that elicit effects on...
Resource Type:: Dissertation
Full Text:: to Dr. Jana Gordon for her support of me as a clinician as well as Dr. Stacie Summers who provided

Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

Creator:: Nagamine, Brandy S.
Abstract:: The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...
Resource Type:: Dissertation
Full Text:: μ8C and salubrinal treatment suppresses synthesis of a model protein...36 2.4.3 4μ8C and

Aspects of the parasite fauna and related diseases in juvenile fishes in Upper Klamath Lake, OR

Creator:: Janik, Andrew J.
Abstract:: Shortnose Sucker (Chasimistes brevirostris) and Lost River Sucker (Deltistes luxatus) are endemic to the Upper Klamath Basin of Southern Oregon and Northern California. Populations of these fishes have been dwindling since the 1960’s and both species where listed to as endangered in 1988. Poor recruitment is thought to be a...
Resource Type:: Masters Thesis
Full Text:: (Anderson and Gordon, 1982; Lester 1984; Markle 2013). These methods have been tested, both in theory

Clinical Applications of Lactate Measurements in Equine Veterinary Medicine

Creator:: Baker, Rose E.
Abstract:: Lactate is an end-product of both aerobic and anaerobic glycolysis and it can be used as an energy source for tissues. It is produced by all cells in the mammalian body that can metabolize glucose. Increased production of lactate can be seen with there is an increase in cellular metabolism...
Resource Type:: Masters Thesis
Full Text:: would also like to thank both Dr. Kirsty Husby and Dr. Emma Gordon for their emotional support

Proteomic Profiles of Circulating Exosomes as Biomarkers for Disease Detection in Canine Osteosarcoma

Creator:: Brady, Jacqueline V.
Abstract:: Osteosarcoma (OSA) is the most common primary skeletal tumor in dogs accounting for 85% of bone tumors and nearly 6% of all canine neoplasms. They are highly aggressive tumors that carry a poor prognosis despite intensive treatment, highlighting the need for more effective diagnostic and therapeutic tools. Recent research in...
Resource Type:: Masters Thesis
Full Text:: serum (FBS; Thermo Fischer Scientific). All cells were maintained at 37°C in a humidified atmosphere

Increasing Vitamin D Levels to Improve Fertilization Rates in Cattle

Creator:: Peixoto de Souza, Vanessa
Abstract:: Recently, an interest in supplementation of vitamin D to improve aspects of health, especially in human fertility, has emerged. However, supplementation of Vitamin D above the minimum required levels to prevent deficiency has yet to be explored in cattle despite evidence for vitamin D receptors in reproductive tissues. The objective...
Resource Type:: Masters Thesis
Full Text:: – ACUP #5139……………………………………………………………... 89 Appendix C – Client Consent Form

Harnessing the Potential of Gut Microbiome in the Context of Type 2 Diabetes

Creator:: Gurung, Manoj
Abstract:: Gut microbiota plays an essential role in health and diseases, a fact already established. With the explosive increase in obesity and its main complication, Type 2 Diabetes Mellitus (T2D), there is an immediate need for novel methods of diagnosis, prevention and treatment of these conditions. In the last one and...
Resource Type:: Dissertation
Full Text:: protein kinase C family (PKCθ), which reduces the activity of IRS27. Along with TAG and DAGs, ceramides

ScholarsArchive@OSU

Characterization of Membrane Vesicles Released by the Opportunistic Human Pathogen Mycobacterium avium subsp. hominissuis (MAH) in Response to an in vitro System Mimicking the Phagosomal Environment

Cannabidiol Effects on NMDA and AMPA Receptor Activity and Cognitive Function at a High Dose in 5xFAD Mice

Molecular Signaling Patterns of the Articular Cartilage and Marginal Transition Zone in Foals with Osteochondrosis

Using the Microbial Tree of Life to Describe Mammalian Health and Disease

Crossing Boundaries during Stress Responses: Antigen Presentation by Adaptive and Innate MHC Class I Molecules

Aspects of the parasite fauna and related diseases in juvenile fishes in Upper Klamath Lake, OR

Clinical Applications of Lactate Measurements in Equine Veterinary Medicine

Proteomic Profiles of Circulating Exosomes as Biomarkers for Disease Detection in Canine Osteosarcoma

Increasing Vitamin D Levels to Improve Fertilization Rates in Cattle

Harnessing the Potential of Gut Microbiome in the Context of Type 2 Diabetes

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