Index Catalog // ScholarsArchive@OSU

Creator:: Ndzeidze, Robert F.
Abstract:: Interference with the host post-translational mechanisms, such as protein phosphorylation, is a key strategy used by many intracellular bacterial pathogens to subvert host immune cell function. Virulent non-tuberculous Mycobacteria (NTMs) unlike attenuated or non-pathogenic NTMs, successfully reside and multiply within the phagosomes of phagocytic cells such as monocytes and macrophages....
Resource Type:: Masters Thesis
Full Text:: W. J. (2017). Nontuberculous Mycobacteria-Overview. Microbiology spectrum, 5(1), 10.1128

Creator:: Nagamine, Brandy S.
Abstract:: The immune system is a complex network of cellular processes working in harmony to guard us against pathogenic attack. Of utmost importance is the ability of the immune system to discriminate between “self” and “non-self” and diseased versus healthy. Recognition of antigens complexed to major histocompatibility complex (MHC) molecules is...
Resource Type:: Dissertation
Full Text:: encoded by the V, J, and C gene segments located on chromosome 14 while the TCR β chain is encoded by

Creator:: Sackinger, Emily P.
Abstract:: Alzheimer’s Disease (AD) is an abnormal part of aging that mainly affects those over the age of 65. The current therapies are only FDA approved for mild to moderate AD symptoms. Cannabidiol (CBD) is a non-intoxicating constituent of Cannabis sativa that has been shown to have beneficial effects on cancer,...
Resource Type:: Masters Thesis
Full Text:: , in AD, known as the amyloid beta hypothesis or the amyloid cascade hypothesis (J. A. Hardy

Creator:: Rojony, Rajoana
Abstract:: M. avium subsp. hominissuis (MAH) and M. abscessus subsp. abscessus (MAB) both belong to the clinically important non-tuberculous mycobacterial (NTM) group that infect immunocompromised patients with AIDS and individuals with underlining lung conditions such as bronchiectasis or cystic fibrosis. The main challenge of treating MAH and MAB patients is an...
Resource Type:: Masters Thesis
Full Text:: J. Gonzalez performed proteome sequencing and analyzed results. L. Danelishvili designed and

Creator:: Islam, Sabrina
Abstract:: Mycobacterium avium subspecies hominissuis (M. avium) is a ubiquitous, acid-fast organism found in water and soil. This opportunistic pathogen is a common causative of pulmonary diseases in immunocompromised individuals and prevalent infection in HIV/AIDS patients. As a primary defense response against infection, immune cells such as macrophages phagocytize M. avium...
Resource Type:: Masters Thesis
Full Text:: 7H10 agar supplemented with 10% OADC (oleic acid albumin, dextrose, and catalase) (Hardy Diagnostics

Creator:: Chiplunkar, Sanket S.
Abstract:: Mycobacterium avium subsp. hominissuis (MAH) belongs to the most-clinically significant non-tuberculous mycobacterial (NTM) pathogens with constant increase in disease prevalence, mainly in several industrialized western countries where tuberculosis is less prevalent. Upon entry into the alveolar space, MAH is engulfed by resident-macrophages, where the pathogen adapts to the hostile phagosomal...
Resource Type:: Masters Thesis
Full Text:: protozoa. MAC are very hardy microbes, showing high tolerance to starvation, extremes of temperature

Creator:: Phillips, Ida L.
Abstract:: Mycobacterium avium subspecies paratuberculosis (MAP) is the causative agent of Johne’s disease, a chronic granulomatous enteritis that plagues domestic and wild ruminants globally. During the silent stages of Johne’s disease, infected animals intermittently shed bacteria for years prior to clinical diagnosis during advanced disease stages. This strategy allows MAP to...
Resource Type:: Dissertation
Full Text:: colostrum (R. J. Whittington et al.). Neonates should be bottle-fed pasteurized colostrum (Stabel). Milk

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