Index Catalog // ScholarsArchive@OSU

Gene-specific antibiotic development: Evaluating effectiveness and investigating antibiotic-resistant Escherichia coli mutants of phosphorodiamidate morpholino oligomers

Creator:: Puckett, Susan E.
Abstract:: Phosphorodiamidate morpholino oligomers (PMOs) are novel antisense drugs in the early stages of development. These synthetic DNA mimics contain the same bases found in DNA and anneal to RNA in a complementary fashion. PMOs have been designed that target genes responsible for producing essential proteins in organisms such as Escherichia...
Resource Type:: Honors College Thesis
Full Text:: project, answering all of my questions, and helping me with my thesis. Finally, thank you Brett Mellbye

A genomic and proteomic characterization of the first cultured oligotrophic marine Gammaproteobacterium from the SAR92 clade

Creator:: Mellbye, Brett L.
Abstract:: High-throughput culturing (HTC) consisting of extinction culturing in autoclaved seawater has led to the isolation and characterization of many novel strains of oligotrophic marine bacteria. Strain HTCC 2207 was isolated from the Oregon coast by the HTC method. Phylogenetic analysis based on 16S rRNA gene sequence showed that this strain...
Resource Type:: Honors College Thesis
Full Text:: THESIS OF Brett L. Mellbye for the degree of Honors Baccalaureate of Science in Microbiology presented

Evaluation of peptide phosphorodiamidate morpholino oligomers as a novel antibiotic therapy

Creator:: Kaller, Margo
Abstract:: Peptide-phosphorodiamidate morpholino oligomers (PPMOs) are synthetic DNA mimics that bind and silence gene targets. Through designing PPMOs that silence essential or resistance genes in pathogens, these antisense oligomers could be utilized as novel antimicrobials. Towards this end, my thesis employed minimum inhibitory concentration assays (MICs) to identify PPMOs capable of...
Resource Type:: Masters Thesis
Full Text:: approved: ______________________________________________________ Bruce L. Geller Peptide

Comparing Sediment Microbial Communities of Arctic Beaver Ponds to Tundra Lakes and Streams

Creator:: Shannon, Kelly
Abstract:: In recent decades the habitat of North American beaver (Castor canadensis) has expanded from boreal forests into pan-Arctic tundra ecosystems. It is unknown how the advance of beavers into Arctic watersheds will impact microbial communities responsible for the mineralization of organic matter (OM), which has implications for carbon cycling. To...
Resource Type:: Masters Thesis
Full Text:: . Carey3, Joshua Koch3, Laura L. Lapham4, Jonathan O’Donnell5, Brett A. Poulin6, Ken D. Tape7, Jason A

Location of Vibrio anguillarum antigen in tissues of immune and non-immune rainbow trout (Salmo gairdneri) using the fluorescent antibody technique

Creator:: Nelson, Jim Steel
Resource Type:: Dissertation
Full Text:: : Redacted for privacy uty. 4. L.'.Fryer To determine the induction mechanism of the immune response in

Social Evolution and Regulatory Architecture of Pseudomonas aeruginosa Quorum Sensing

Creator:: Asfahl, Kyle L.
Abstract:: Cell-cell communication in bacteria is understood to facilitate the coordination of population-wide cooperative behavior in the form of concerted gene expression. The opportunistic pathogen Pseudomonas aeruginosa uses such a communication mechanism to regulate a large group of genes important to virulence strategies in this bacterium. This general mechanism of communication...
Resource Type:: Dissertation
Full Text:: Kyle L. Asfahl for the degree of Doctor of Philosophy in Microbiology presented on June 8, 2017

Investigation of Nematocyst Discharge in Parasitic Cnidarians (Myxozoa)

Creator:: Americus, Benjamin E.
Abstract:: Myxozoans are an enigmatic group of obligately parasitic, microscopic cnidarians. They diverged from their free-living relatives over 600 million years ago and have highly reduced genomes. However, they have retained nematocyst stinging cells which characterize the phylum Cnidaria. Free-living cnidarians utilize this cellular weaponry for defense and predation whereas the...
Resource Type:: Masters Thesis
Full Text:: troubleshooting. I am indebted to the staff at the John L. Fryer Aquatic Animal Health Laboratory and my lab

Characterization of Baculovirus genes involved in genome replication and processing

Creator:: Vanarsdall, Adam L.
Abstract:: The Baculoviridae comprise a diverse group of occluded DNA viruses that contain large double-stranded DNA genomes of 80 - 180 kb and may encode up to 180 gene products. To understand how baculoviruses replicate and process their genomes and the gene products that are involved in these events, a series...
Resource Type:: Dissertation
Full Text:: in genome replication and processing.doc 2 AN ABSTRACT OF THE THESIS OF Adam L

The effects of single and multiple pathogen and parasite infections on juvenile chinook and coho salmon during early marine residency

Creator:: Sandell, Todd A.
Abstract:: Nearly 3000 juvenile Chinook (Oncorhynchus tshawytscha) and coho (O. kisutch) salmon captured in nearshore waters off the coasts of Washington and Oregon from 1999-2004 were tested for infection by Renibacterium salmoninarum, Nanophyetus salmincola, and skin metacercariae. First, three quantitative PCR primer/probe sets were compared for detection of R. salmoninarum; amplification...
Resource Type:: Dissertation
Full Text:: : ___________________________________________________________ Jerri L. Bartholomew Nearly 3000 juvenile Chinook (Oncorhynchus tshawytscha) and

Host-pathogen Interactions of Respiratory RNA Viruses and the Application of Recombinase Polymerase Amplification for Viral Diagnostics

Creator:: Prescott, Meagan A.
Abstract:: Humans and viral disease are inextricably intertwined. Viral disease plays an immeasurable role in human life, from the disease and economic burden associated with every facet of contending with human viral disease, to managing the consequences of viral disease in organisms important to our food supply, economy, and entertainment. The...
Resource Type:: Dissertation
Full Text:: polymerase (L), and M2 encoded (M2-1) protein (Ghildyal, Ho, and Jans 2006). 11

ScholarsArchive@OSU

Gene-specific antibiotic development: Evaluating effectiveness and investigating antibiotic-resistant Escherichia coli mutants of phosphorodiamidate morpholino oligomers

A genomic and proteomic characterization of the first cultured oligotrophic marine Gammaproteobacterium from the SAR92 clade

Evaluation of peptide phosphorodiamidate morpholino oligomers as a novel antibiotic therapy

Comparing Sediment Microbial Communities of Arctic Beaver Ponds to Tundra Lakes and Streams

Location of Vibrio anguillarum antigen in tissues of immune and non-immune rainbow trout (Salmo gairdneri) using the fluorescent antibody technique

Social Evolution and Regulatory Architecture of Pseudomonas aeruginosa Quorum Sensing

Investigation of Nematocyst Discharge in Parasitic Cnidarians (Myxozoa)

Characterization of Baculovirus genes involved in genome replication and processing

The effects of single and multiple pathogen and parasite infections on juvenile chinook and coho salmon during early marine residency

Host-pathogen Interactions of Respiratory RNA Viruses and the Application of Recombinase Polymerase Amplification for Viral Diagnostics

Limit your search

Academic Affiliation

Advisor

Commencement Year

Committee Member

Creator

Contributor

Date

Decade

Degree Field

Degree Level

Degree Name

File Format

Language

License

Non-Academic Affiliation

Peer Reviewed

Resource Type

Rights Statement

Subject

Search Constraints

Search Results

Limit your search