Index Catalog // ScholarsArchive@OSU

DNA vaccines encoding the glycoprotein genes of spring viremia of carp virus, snakehead rhabdovirus, or infectious hematopoietic necrosis virus induce protective immunity in rainbow trout (Oncorhynchus mykiss) against an infectious hematopoietic necrosis virus lethal challenge

Creator:: Drennan, John D.
Abstract:: Recent advances in DNA vaccine technology has brought about a promising strategy for the control of viruses that contain surface membrane glycoproteins. This type of vaccine involves the intramuscular injection of a bacterial plasmid containing a gene encoding a viral protein. The strategy uses eukaryotic processing of the protein as...
Resource Type:: Masters Thesis
Full Text:: induced by these glycoprotein based DNA vaccines is unknown. A parallel study conducted by Dr. Carol Kim

RNA-directed DNA polymerase activity in human placentas

Creator:: Nelson, Jay A.
Resource Type:: Dissertation
Full Text:: approved: Redacted for privacy I JO-Ann Ching Leong/ ABSTRACT Major efforts have been made to detect the

A molecular study of viral proteins in the pathogenesis of infectious hematopoietic necrosis virus

Creator:: Chiou, Pinwen Peter
Abstract:: The role of viral proteins in the pathogenesis of infectious hematopoietic necrosis virus (IHNV) was studied at the molecular level. The expression of the viral genes at the protein and RNA level, and their cellular localization, were characterized to further our understanding of viral pathogenesis. The pathogenic effect of individual...
Resource Type:: Dissertation
Full Text:: : Jo-Ann C Leong The role of viral proteins in the pathogenesis of infectious hematopoietic necrosis

Molecular characterization of the MX genes of rainbow trout (Oncorhynchus mykiss)

Creator:: Trobridge, Grant David
Abstract:: The Mx protein family of rainbow trout (Oncorhynchus mykiss) was characterized at the molecular level. With primers derived from a partial sequence of Perch (Perca fluviatis) Mx genomic DNA, a partial rainbow trout Mx genomic DNA sequence was obtained by polymerase chain reaction (PCR) amplification. All salmonid fish investigated contained...
Resource Type:: Dissertation
Full Text:: of Rainbow Trout (Oncorhynchus vkiss). Abstract approved: Jo-Ann C. Leong The Mx protein

Recombinant vaccines against infectious hematopoietic necrosis virus : bacterial systems for vaccine production and delivery

Creator:: Simon, Benjamin E.
Abstract:: Several systems were examined for the production and delivery of recombinant vaccines for fish. C. crescentus was employed to produce a fragment of the IHNV glycoprotein. When administered by injection to 0.5 gram rainbow trout (Oncorhynchus mykiss), one of the fusion proteins (184 amino acids of the IHNV glycoprotein fused...
Resource Type:: Dissertation
Full Text:: Vaccine Production and Delivery. Abstract approved: Jo-Ann C. Leong Several systems were examined for

Pathogenic and molecular characterization of three closely related isolates of infectious pancreatic necrosis virus (IPNV)

Creator:: Bruslind, Linda D.
Abstract:: Three closely related isolates belonging to the A₁ serotype of infectious pancreatic necrosis virus (IPNV) were selected for comparison, to provide insight into the nature of variation in the virulence of IPN viruses. Brook trout fry (Salvelinus fontinalis) were experimentally infected with the three isolates by immersion. Cumulative mortalities over...
Resource Type:: Dissertation
Full Text:: committee members: Dr. Paul Reno, my major professor, Dr. Jo-Ann Leong, Dr. Rich Holt, Dr. Robert Olson

Transmission of disseminated neoplasia in the soft shell clam, Mya arenaria

Creator:: House, Marcia
Abstract:: Disseminated neoplasia (DN) is a proliferative cell disorder that occurs in the circulatory system of bivalves. The condition is progressive and lethal. At least 15 species of bivalves over a wide range of geographic locations have been reported to contract DN. Prevalence levels of disseminated neoplasia can reach up to...
Resource Type:: Dissertation
Full Text:: , Dr. Jo-Ann Leong, Dr. Chris Langdon, Dr. Anja Robinson, and Dr. Michael Mix, for their support. I am

Studies on purification and characterization of an autolytic enzyme from cell walls of Bacillus subtilis

Creator:: Brown, Willie Claiborne
Abstract:: The purpose of this investigation was to purify and characterize the autolytic enzyme from cell walls of Bacillus subtilis 168. The crude enzyme was obtained by autolysis of purified cell walls in buffer at 37° C. Two purification methods were developed. The first involved fractional precipitation with ammonium sulfate. The...
Resource Type:: Dissertation
Full Text:: . "The Group" : Carol Kurahara, Patti -Jo Laudermilk, Carol Richter Brantner and Gerry Anderson for the

Analysis of immune modulators in rainbow trout (Oncorhynchus mykiss)

Creator:: Mourich, Dan V.
Abstract:: The immune systems of various teleost fish have been studied in some detail for the past several decades. One aspect of fish immunity, that of endogenously produced modulating factors, has recently received a great deal of attention. Understanding the functions and roles of endogenous factors that regulate fish immunity is...
Resource Type:: Dissertation
Full Text:: ACKNOWLEDGMENTS The one person most instrumental in making this thesis possible was Dr. Jo-Ann Leong. Without

Bdellovibrio metabolism of host macromolecules

Creator:: Engelking, Henry Mark
Abstract:: The genus Bdellovibrio is characterized by the unique ability to parasitize and enter gram-negative host bacteria. This interaction leads to the consumption and death of the host cell as the Bdellovibrio grows and divides into progeny. Little is known about the metabolism of host cell components by Bdellovibrio. The possibility...
Resource Type:: Masters Thesis
Full Text:: privacy Dean of Graduate School Date thesis is presented March 12, 1974 Typed by Mary Jo Stratton for

ScholarsArchive@OSU

DNA vaccines encoding the glycoprotein genes of spring viremia of carp virus, snakehead rhabdovirus, or infectious hematopoietic necrosis virus induce protective immunity in rainbow trout (Oncorhynchus mykiss) against an infectious hematopoietic necrosis virus lethal challenge

RNA-directed DNA polymerase activity in human placentas

A molecular study of viral proteins in the pathogenesis of infectious hematopoietic necrosis virus

Molecular characterization of the MX genes of rainbow trout (Oncorhynchus mykiss)

Recombinant vaccines against infectious hematopoietic necrosis virus : bacterial systems for vaccine production and delivery

Pathogenic and molecular characterization of three closely related isolates of infectious pancreatic necrosis virus (IPNV)

Transmission of disseminated neoplasia in the soft shell clam, Mya arenaria

Studies on purification and characterization of an autolytic enzyme from cell walls of Bacillus subtilis

Analysis of immune modulators in rainbow trout (Oncorhynchus mykiss)

Bdellovibrio metabolism of host macromolecules

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