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Filtering by: Creator Bahk, Jang-Jun Degree Field Molecular and Cellular Biology

Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

Creator:

Zhang, Yong

Abstract:

Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled signaling pathways. Prior research suggested that some isoforms of PLC-β may exist and function as dimers, but little is known about dimerization of PLC-β. Data from coimmunoprecipitation assays of differentially-tagged PLC-β constructs and sizeexclusion chromatography of native PLC-β support homodimerization...

Resource Type:

Dissertation

Full Text:

) of PLC-β1a is replaced by 32 amino acids (residues 1142-1173) of PLC-β1b (Bahk et al., 1994
Investigating Protein-lipid-membrane Interactions in Plant Cells using Bimolecular Fluorescence Complementation

Creator:

Tao, Kai

Abstract:

The overall focus of this thesis is on the distribution of specific lipids and membrane proteins of the external and internal membranes of plant cells, in the context of the roles that those lipids and proteins may play in microbe-plant interactions. The work includes the development of several new tools,...

Resource Type:

Dissertation

Full Text:

superresolution imaging, and his lab member Tao Huang, Jing Wang, Linli Jun, Carey, Ying Zhang, Yerim lee gave