Index Catalog // ScholarsArchive@OSU

Genome-enabled discovery and characterization of type III effector-encoding genes of plant symbiotic bacteria

Creator:: Kimbrel, Jeffrey A.
Abstract:: Symbiosis is the close and protracted interaction between organisms. The molecular interactions that occur during symbiosis are complex with multiple barriers that must be overcome. Many Gram-negative, host-associated bacteria use a type III secretion system to mediate associations with their eukaryotic hosts. This secretion system is a specialized apparatus for...
Resource Type:: Dissertation
Full Text:: Effector- encoding Genes of Plant Symbiotic Bacteria. Abstract approved: Jeff H. Chang

Alternative splicing in the obligate biotrophic oomycete pathogen, Pseudoperonospora cubensis

Creator:: Cumbie, Jason S.
Abstract:: Oomycetes are some of the most devastating pathogens, causing upwards of billions of dollars of damage each year to plants. They also diminish ecological diversity and health through the destruction of trees and shrubs. The genome sequence of Pseudoperonospora cubensis, an obligate plant pathogen and causative agent of downy mildew...
Resource Type:: Dissertation
Full Text:: : __________________________________________________________ Jeff H. Chang Oomycetes are some of the most devastating pathogens, causing upwards of

Identification and characterization of type III effector proteins in plant-associated bacteria

Creator:: Thomas, William J.
Abstract:: Symbioses between microbes and multicellular eukaryotes are found in all biomes, and encompass a spectrum of symbiotic lifestyles that includes parasitism and disease, commensalism, and mutually beneficial interdependent host-microbe relationships. Regardless of outcome, these symbiotic lifestyles are governed by a complex molecular "courtship" between microbe and potential host. This courtship...
Resource Type:: Dissertation
Full Text:: : ________________________________________________________________________ Jeff H. Chang Symbioses between microbes and multicellular eukaryotes are found in all

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Creator:: Creason, Allison L.
Abstract:: Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe growth deformities on a large range of hosts. The most well studied species, R. fascians is predicted by current models to synthesize a mixture of cytokinins that act to directly perturb the hosts' hormone balances, which results in abnormal...
Resource Type:: Dissertation
Full Text:: . Chang Plant pathogenic Rhodococcus species are persistent pathogens able to cause severe

Phylogeny and Evolution of Gall-Associated Plant Pathogenic Bacteria

Creator:: Davis, Edward W., II
Abstract:: Gall-associated phytopathogens have unique evolutionary histories that haveshaped both their modes of infection and genomic structures. Pathogenicity of the gall-associated plant pathogens of the Rhodococcus, Agrobacterium, and Rathayibactergenera is mediated by horizontally acquired virulence loci. The relative ease of gainand loss of the virulence loci has confounded accurate characterization of...
Resource Type:: Dissertation
Full Text:: . Abstract approved: ______________________________________________________ Jeff H. Chang Gall

Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

Creator:: Zhang, Yong
Abstract:: Phospholipase C-β (PLC-β) isozymes are key effectors in G protein-coupled signaling pathways. Prior research suggested that some isoforms of PLC-β may exist and function as dimers, but little is known about dimerization of PLC-β. Data from coimmunoprecipitation assays of differentially-tagged PLC-β constructs and sizeexclusion chromatography of native PLC-β support homodimerization...
Resource Type:: Dissertation
Full Text:: . Paul Murtaugh, Dr. Claudia Maier and Dr. Lan Xue for their invaluable support and feedback during

Quorum-sensing-controlled public goods in Pseudomonas aeruginosa : regulation and application

Creator:: Mellbye, Brett L.
Abstract:: Cell-to-cell communication by chemical signals, termed quorum sensing (QS), is a common regulatory scheme in the microbial world. Pseudomonas aeruginosa¸ an opportunistic pathogen of burn wounds and cystic fibrosis lungs, uses QS to control the expression of hundreds of genes, particularly those necessary for population level benefits such as biofilm...
Resource Type:: Dissertation
Full Text:: thank my committee members: Dr. Jeff Chang, Dr. Bruce Geller, Dr. Walt Ream, and Dr. Roger Ely, who

Transcriptomic analysis using high-throughput sequencing and DNA microarrays

Creator:: Fox, Samuel E.
Abstract:: Transcriptomics and gene expression profiling enables the elucidation of the genetic response of an organism to various environmental cues. Transcriptomics enables the deciphering of differences between two closely related organisms to the same environment and in contrast, enables the elucidation of genetic responses of the same organism to different environmental...
Resource Type:: Dissertation
Full Text:: Indra, Michael Freitag, and especially Jeff Chang and Barbara Taylor. I’d like to thank all my friends

Genomic Resource Development for European Hazelnut (Corylus avellana L.)

Creator:: Rowley, Erik R.
Abstract:: European hazelnut (Corylus avellana L.) is an important crop Oregon's Willamette Valley, producing 99% of the hazelnuts grown in North America and brings over US $60 million dollars to the region annually. Hazelnuts are rich in fiber and vitamins, as well in demand by consumers due to their popularity as...
Resource Type:: Dissertation

The role of keratinocytic RXRα in regulating melanocyte homeostasis and carcinogen induced melanomagenesis, The role of keratinocytic RXR[alpha] in regulating melanocyte homeostasis and carcinogen induced melanomagenesis

Creator:: Hyter, Stephen D.
Abstract:: Cutaneous melanoma remains the deadliest form of skin cancer, with a diagnosis of metastasis indicating a median survival rate of less than a year. Solar ultraviolet (UV) radiation, especially childhood sun exposure, is an important etiological risk factor of melanoma. Previous studies determined that mice selectively lacking the nuclear hormone...
Resource Type:: Dissertation
Full Text:: formation in a mouse model (Chang et al., 2008). The anti-inflammatory actions of LXR activators have

ScholarsArchive@OSU

Genome-enabled discovery and characterization of type III effector-encoding genes of plant symbiotic bacteria

Alternative splicing in the obligate biotrophic oomycete pathogen, Pseudoperonospora cubensis

Identification and characterization of type III effector proteins in plant-associated bacteria

Characterization of the pathogenicity and phylogeny of members of the Rhodococcus genus

Phylogeny and Evolution of Gall-Associated Plant Pathogenic Bacteria

Some potential mechanisms for finely-tuned regulation of phospholipase C-β isozymes : studies of dimerization and phosphatidylinositol 3,4,5-trisphosphate activation

Quorum-sensing-controlled public goods in Pseudomonas aeruginosa : regulation and application

Transcriptomic analysis using high-throughput sequencing and DNA microarrays

Genomic Resource Development for European Hazelnut (Corylus avellana L.)

The role of keratinocytic RXRα in regulating melanocyte homeostasis and carcinogen induced melanomagenesis, The role of keratinocytic RXR[alpha] in regulating melanocyte homeostasis and carcinogen induced melanomagenesis

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