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Filtering by: Creator Enright, Chris Remove constraint Creator: Enright, Chris Degree Field Molecular and Cellular Biology Remove constraint Degree Field: Molecular and Cellular Biology

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  • Transcriptomic Analyses of Crop Plants using Next-Generation Sequencing Technology

    Creator:
    Geniza, Matthew J.
    Abstract:
    Advancements in molecular biology and computer science have enabled researchers the ability to investigate the transcriptome – the quantification of an organism’s RNA transcripts in response to its environment on a system wide scale. The collective chapters of this thesis utilize high-throughput RNA sequencing, which produces hundreds of millions of...
    Resource Type:
    Dissertation
    Full Text:
    Award. To my study group; Edward Davis, Kai Tao, Estefania Elorriaga, and Chris Sullivan – without

  • Genomic characterization of a novel leporid Herpes simplex virus

    Creator:
    Babra, Bobby A.
    Abstract:
    The viral family Herpesviridae consists of large double stranded DNA viruses including eight species that infect humans with varying pathology from benign rashes to cancerous cell transformation. From three subfamilies, alpha-, beta- and gammaherpes, the alphaherpes contains the genera iltovirus, mardivirus, varicellovirus and simplex, two of which, the human simplex...
    Resource Type:
    Dissertation
    Full Text:
    bioinformatics. I would like to give my appreciation to Chris Sullivan and Dr. James Carrington. To my

  • Origins and evolution of plant microRNA genes

    Creator:
    Fahlgren, Noah
    Abstract:
    Eukaryotic small RNA (~20-30 nucleotides) are diverse regulatory molecules that repress gene expression at the transcriptional and post-transcriptional levels, defend hosts against invading viruses and defend genomes against selfish DNA elements. Small RNA populations are studied by high-throughput sequencing of the total small RNA fraction isolated from cells, however, the...
    Resource Type:
    Dissertation
    Full Text:
    Zhixin Xie for guidance; Chris Sullivan, Scott Givan and Jason Cumbie for computational guidance

  • Processing and functional diversity of plant microRNA

    Creator:
    Cuperus, Josh
    Abstract:
    RNA interference pathways can involve amplification of secondary siRNAs by RNA-dependent RNA polymerases. In plants, RDR6-dependent secondary siRNAs, including transacting siRNAs (tasiRNAs), arise from transcripts targeted by some microRNAs (miRNAs). In the case of TAS3 tasiRNA formation, ARGONAUTE7 (AGO7)-miR390 complexes interact with primary transcripts at two sites, resulting in recruitment...
    Resource Type:
    Dissertation
    Full Text:
    , Atsushi Takeda, and Taiowa Montgomery for guidance; Chris Sullivan and Noah Fahlgren for computational