Index Catalog // ScholarsArchive@OSU

Creator:: Xiao, Ying-Yi
Abstract:: The first goal of this study was to understand the role of u-calpain in skeletal muscle protein degradation in cultured muscle cells. Several strategies were developed to down-regulate endogenous u-calpain activity and m-calpain activity in rat myotubes. These included over-expression of antisense u-calpain (AnsL), dominant negative u-calpain (DN-u-CL), antisense 30K...
Resource Type:: Dissertation
Full Text:: :6880-9. 13 37. Strobi S., Fernandez-Catalan C., Braun M., Huber R., Masumoto H., Nakagawa K., Irie

Creator:: Mellbye, Brett L.
Abstract:: Cell-to-cell communication by chemical signals, termed quorum sensing (QS), is a common regulatory scheme in the microbial world. Pseudomonas aeruginosa¸ an opportunistic pathogen of burn wounds and cystic fibrosis lungs, uses QS to control the expression of hundreds of genes, particularly those necessary for population level benefits such as biofilm...
Resource Type:: Dissertation

Creator:: Cumbie, Jason S.
Abstract:: Oomycetes are some of the most devastating pathogens, causing upwards of billions of dollars of damage each year to plants. They also diminish ecological diversity and health through the destruction of trees and shrubs. The genome sequence of Pseudoperonospora cubensis, an obligate plant pathogen and causative agent of downy mildew...
Resource Type:: Dissertation
Full Text:: , 2007; Anders and Huber, 2010; Di et al., 2011). While sequencing costs have been greatly reduced

Creator:: Lattier, Vera C.
Abstract:: Skeletal muscle, the largest organ in the body in mass, is composed by 600 specialized muscles in humans with unique biochemical, physiological and metabolic identities. Skeletal muscles control body movement, locomotion, and nutrient balance. Muscle formation requires precisely orchestrated environmental signals and regulatory gene networks in time and space. Gene...
Resource Type:: Dissertation

Creator:: Kimbrel, Jeffrey A.
Abstract:: Symbiosis is the close and protracted interaction between organisms. The molecular interactions that occur during symbiosis are complex with multiple barriers that must be overcome. Many Gram-negative, host-associated bacteria use a type III secretion system to mediate associations with their eukaryotic hosts. This secretion system is a specialized apparatus for...
Resource Type:: Dissertation

Creator:: Vondras, Amanda M.
Abstract:: In the study of any developmental process, whether in plants, animals, or other models, it is prudent to consider the developmental position of the subjects being measured. This is generally not taken into consideration in grapevine studies despite a growing body of literature documenting that fruits within clusters develop and...
Resource Type:: Dissertation

Creator:: Lu, Wanli
Abstract:: Among the myriad of naturally occurring bioactive compounds are the aminocyclopentitol-containing natural products that represent a family of sugar-derived microbial secondary metabolites, such as the antibiotics pactamycin, allosamidin, and trehazolin. Pactamycin, a structurally unique aminocyclitol antibiotic isolated from Streptomyces pactum, consists of a 5-membered ring aminocyclitol (cyclopentitol) unit, two aromatic...
Resource Type:: Dissertation

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