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Filtering by: Committee Member Buhler, Donald Remove constraint Committee Member: Buhler, Donald Degree Field Pharmacology and Toxicology Remove constraint Degree Field: Pharmacology and Toxicology

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  • Intracellular pH and the uptake of carcinostatic drugs by selected experimental tumors

    Creator:
    Hult, Richard Lee
    Abstract:
    The relationship of intracellular drug levels and resultant drug activity to intracellular pH (pHi) was studied in the experimental tumors. Glucose (5 g/kg) and/or sodium oxamate (0.1 mmol) were administered to Walker 256 ascites cells and Ehrlich ascites cells, in an attempt to alter pHi as measured by the distribution...
    Resource Type:
    Dissertation
    Full Text:
    , Dr. Donald Buhler, and Dr. Fred Hisaw. Their encouragement and constructive comments during the