Index Catalog // ScholarsArchive@OSU

Structure elucidation of bioactive natural products from Madagascar marine algae and cyanobacteria

Creator:: Andrianasolo, Eric Hajaniriana
Abstract:: This thesis is an investigation of the natural products deriving from marine algae and cyanobacteria and has resulted in the discovery of eleven new secondary metabolites. The structure elucidations of these new molecules were performed using a variety of spectroscopic techniques. Four new macrolides were isolated and characterized from the...
Resource Type:: Dissertation
Full Text:: from Madagascar Marine Algae and Cyanobacteria Abstract approved: William H. Gerwick

Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

Creator:: Han, Bingnan
Abstract:: This thesis details my investigations of marine cyanobacterial natural products that resulted in the discovery of eighteen new secondary metabolites. Isolation and characterization of these unique molecules were carried out using different chromatographic techniques and by careful analyses of 1D and 2D NMR data, respectively. Preliminary bioassays of the crude...
Resource Type:: Dissertation
Full Text:: gratitude to my major advisor, Dr. William Gerwick, and my committee members, Dr. Philip Proteau, Dr

Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

Creator:: Milligan, Kenneth Edward
Abstract:: This thesis describes investigations of marine algal secondary metabolites, with particular interest in their biomedical and agrichemical potential. Invaluable in such pursuits have been the access and application of advanced spectroscopic techniques, such as NMR, and the ability to assess the biological activity of the algal samples in a variety...
Resource Type:: Dissertation
Full Text:: Secondary Metabolites of Unique Structure and Biomedicinal or Agrichemical Potential. Abstract William H

New bioactive natural products from marine algae and cyanobacteria

Creator:: Sabry, Omar Mohamed
Abstract:: This thesis is an account of investigation on the natural products deriving from various marine algae and has resulted in the discovery of eleven novel bioactive metabolites. Isolation and characterization of these new molecules were carried out using different chromatographic techniques and by analyses of different spectroscopic data, respectively. Using...
Resource Type:: Dissertation
Full Text:: I would like to thank my major advisor, Dr. William H. Gerwick, for his exceptional generous

The natural products chemistry of the red algae Ptilota filicina and Laurencia obtusa

Creator:: Lopez, Albert
Abstract:: The sea offers a wide variety of potentially useful resources. Marine algae have been a rich source of structurally unique natural products showing diverse biological properties. The current need to develop new antifungal, antibiotic, anticancer and antiviral drugs has prompted intense research efforts into the discovery, isolation and structure determination...
Resource Type:: Masters Thesis
Full Text:: Ptilota filicina and Laurencia obtusa Abstract approved: Redacted for Privacy Dr. William H. Gerwick

Natural products from tropical and temperate marine algae

Creator:: Bernart, Matthew W.
Abstract:: Following surveys of seaweeds in Oregon and the Caribbean, four algal species were selected for study on the basis of their crude extract biological activity or thin-layer chromatographic characteristics. Extracts were fractionated by normal phase chromatography, including high performance liquid chromatography (HPLC). Derivatives (methyl esters, acetates, and benzoates) of natural...
Resource Type:: Dissertation
Full Text:: Algae Abstract approved: Redacted for Privacy William H. Gerwick Following surveys of seaweeds in

Novel oxylipins and other bioactive metabolites from marine algae

Creator:: Nagle, Dale George
Abstract:: I have participated in a drug discovery program designed to screen marine algae for inhibitors of cancer-related enzymes, antitumor compounds, antiinflammatory substances, and other agents of potential pharmaceutical utility. Over 1,500 lipid and aqueous extracts of marine plants and animals were surveyed for biomedical potential. Assays designed to screen extracts...
Resource Type:: Dissertation
Full Text:: Bioactive Metabolites From Marine Algae Abstract approved: William H. Gerwick I have participated in a

Cardiovascular effects of trimethobenzamide

Creator:: Benslay, Don Nolan
Resource Type:: Masters Thesis
Full Text:: Lilly Atropine s. B. Penick &Company llbtamine Diphosphate Abbott Laboratories The pentobarbital

Product formulation of phenylbutazone, theophylline, tolbutamide and pharmacokinetics-toxicities of theophylline injections in pigs

Creator:: Suvanakoot, Uthai
Abstract:: A two-part study was conducted with three poorly water soluble drugs (phenylbutazone, tolbutamide, theophylline) to develop two new drug delivery systems based on physical-chemical approaches. In the first part, tolbutamide and phenylbutazone were made into solid dispersions with various excipients using a lyophilization technique. In vitro dissolution studies of these...
Resource Type:: Dissertation

Synthesis and opioid activity of dynorphin analogues with the modifications in the message sequence

Creator:: Kulkarni, Sandhya N.
Resource Type:: Masters Thesis
Full Text:: . William Remers and Dr. Arnold Martin, Professors, Medicinal Chemistry, (University of Arizona, Tucson

ScholarsArchive@OSU

Structure elucidation of bioactive natural products from Madagascar marine algae and cyanobacteria

Natural products studies of the marine cyanobacteria Lyngbya semiplena and Lyngbya majuscula

Marine algal secondary metabolites of unique structure and biomedicinal or agrichemical potential

New bioactive natural products from marine algae and cyanobacteria

The natural products chemistry of the red algae Ptilota filicina and Laurencia obtusa

Natural products from tropical and temperate marine algae

Novel oxylipins and other bioactive metabolites from marine algae

Cardiovascular effects of trimethobenzamide

Product formulation of phenylbutazone, theophylline, tolbutamide and pharmacokinetics-toxicities of theophylline injections in pigs

Synthesis and opioid activity of dynorphin analogues with the modifications in the message sequence

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