Chlorinated and non-chlorinated solvents are used in a variety of industrial processes and as a consequence, they have become environmental contaminants as well. Because of this, they lead to both occupational and environmental exposures. Exposure to these compounds can potentially result in various forms of neurological damage with a wide...
Mammary tumors are the third most common tumor in cats after cutaneous neoplasia and lymphosarcoma. More than 80% of feline mammary tumors are adenocarcinomas, which are similar to human mammary adenocarcinomas in their biologic behavior and histologic characteristics. Despite treatment with radical mastectomy, feline mammary adenocarcinoma is associated with a...
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White muscle disease (WMD), a degenerative muscle disease brought on by a deficiency of the essential trace nutrient selenium, is thought to be mediated by the protein Selenoprotein W (SeW). In its relationship with WMD, SeW, like many selenoproteins, binds to glutathione, serving some purpose in redox mechanisms...
The AhR is a ligand-activated transcription factor that mediates the potent immunosuppressive effects of TCDD. AhR-dependent changes in gene expression appear to alter the differentiation of CD4+ T cells to induce a population of CD4+CD25+ T regulatory cells (Tregs) that suppress the immune response. Ascertaining if and how the AhR...
Consider a simple Markov process on [0,T]. The occupation times were extensively studied in the case of T increasing to infinity. Here we develop a method of computing the distribution for occupation times when T is small via integral equations and integral transforms.
Inflammation is one of the first, most important responses of the immune system when presented with infection and is mediated primarily by eicosanoids and cytokines. The goal of this research was to generate monoclonal antibodies against murine IL17C, a poorly characterized cytokine involved in inflammation and linked to inflammatory conditions....
The endoplasmic reticulum (ER) is a crucial organelle in the cell where protein folding and processing occurs, and conditions that negatively affect ER functions are highly detrimental to the cell. The accumulation of unfolded/misfolded proteins in the ER leads to a condition known as ER Stress. The ER has developed...
The Harderian gland (HG) of the red-sided garter snake, Thamnophis sirtalis parietalis, is a secretory structure that plays a role in the vomeronasal system by solubilizing semiochemicals such as prey chemoattractants and the female sexual attractiveness pheromone. The HG produces secretions containing pheromone-binding proteins that form a complex with pheromone...
Although thousands of volunteers from the United States go abroad each year to teach English, many are unprepared for their experiences. Undergraduate students teaching in a foreign country seem to lack training in educational methodology or foreign relations that would prepare them for teaching and living abroad. This project was...
Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...
Vox comm is a digital wireless, voice-operated personal communicator developed as an electrical engineering Senior Design project. It is designed to provide a method for hassle-free, short-range communication. The product platform boasts of low power and small size for a host of usage models. This thesis details the product design...
It is commonly accepted that for the analysis of wood beams, the neutral axis coincides with the centroid of the beam. Although this assumption is used in analysis, wood is not an isotropic material, as it has different elastic properties in the tangential, radial and longitudinal directions, nor is it...
An inducible, mutant virus, designated vvtetO:I7L/G1L, was used to study the morphogenic proteolysis step of the vaccinia virus life cycle. The vvtetO:I7L/G1L controlled the expression of two genes, I7L, a cysteine proteinase, and G1L, a putative metalloproteinase. These proteins are involved in the maturation of viral core proteins, p4a, p4b,...
Intimate partner violence is the systematic, intentional use of physical, emotional and/or sexual abuse that one person in a domestic relationship exerts over their partner in order to maintain power and control. In our society, we tend to focus on the external evidence of intimate partner violence such as the...
As genetically modified products come under greater production, tensions surrounding the potential benefits and harms of the technology have appeared in divergent policy between the European Union (EU) and certain member states. The purpose of this thesis is to consider whether some type of international law, also called an environmental...
Twenty seven modern (top 1-2cm) sediment samples from multicores retrieved from throughout coastal SE Alaska were analyzed for their organic matter content and the source composition. Total organic carbon (TOC) as well as biogenic silica (bioSi), and calcium carbonate (CaCO3) content were analyzed to evaluate the organic matter content and...
Rhodococcus fascians is a Gram-positive, pleiomorphic actinomycete that causes leafy gall formation in a wide range of plant hosts. This particular phytopathogen has been a focus of research at the Oregon State University Plant Clinic, a diagnostic laboratory. Phylogeny of R. fascians isolates obtained from Plant Clinic submissions was determined...
Empowering pedagogy (also know as “transgressive,” “emancipatory,” or “democratic” forms of education) seeks to challenge the historically oppressive tendencies of traditional education. As a student of Social Justice and International Studies, I approach the topic of empowering pedagogy through a case study. My research explored this non-traditional educational philosophy and...
This study compares the accounting standards of three different entities, the United Kingdom Generally Accepted Accounting Principles, the domestic accounting standards of France, and the International Financial Reporting Standards (IFRS). The analysis consists of a comparison between two companies, British Airways and Air France – KLM, for FY 2005, specifically...
Spending time in a German speaking country may aid in vocabulary acquisition and production. This study hypothesized a concrete link between written language use and experiences abroad. Intermediate German students’ vocabulary uses in impromptu essays were evaluated by counting the number of total word, unique words, and content words. This...
The bovine blastocyst is composed of a one-celled layer of trophectoderm
surrounding a fluid filled sac called the blastocoel and a ball of cells called the inner cell
mass (ICM). On Day 8 (Day 0=fertilization) in bovine embryos, endodermal cells leave
the ICM, migrate over the extracellular matrix (ECM) on...
Mitochondria provide energy for biological cells to function, but this process is also a source of oxygen radicals that are capable of damaging nearby proteins. Mitochondrial protein damage can eventually lead to cell death, especially in the case of heart cells, where mitochondria are present in the highest concentrations. As...
This study was conducted to support a research project sponsored by the National Science Foundation (NSF). The purpose of the NSF research project was to determine how to design kaizen events that result in both short term and long term performance improvements. One of the tools developed to evaluate the...
Clostridium perfringens type A isolates produce the spore-specific enterotoxin, CPE, upon sporulation in the gastrointestinal tract of humans and animals. Spo0A is a response regulator representing the major transcription factor for sporulation initiation in C. perfringens. In Bacillus subtilis, a multicomponent phosphorelay involving five histidine kinases (KinA-KinE), the intermediate response...
The decisions in Solid Waste Agency of Northern Cook County v. U.S. Army Corps of Engineers, 531 U.S. 159 (2001) (SWANCC) and Rapanos v. United States, 547 U.S. ___(2006), deviated from the more broad interpretations of congressional intent granted by the court in past assessments of the constitutionality of environmental...
The debate over GM crops is one of the most controversial issues of recent decades. The debate has many dimensions, including environmental impacts, benefits and risks to human health, intellectual property rights, adequacy of biosafety regulations, and fundamental ethical acceptability. The potential benefits of GM crops are numerous, including improved...
Winter hardiness in barley (Hordeum vulgare) is a trait targeted by breeding programs in order to expand the potential area of adaptation of fall-sown cereals. Vernalization requirement is an important factor in winter hardiness. A vernalization requirement is an extended period of low temperature required for transition from the vegetative...
We are developing a flavin-containing (Fmo) knock-out mouse for Fmo2 that will be utilized to elucidate the role of active human FMO isoform 2 (FMO2.1) in xenobiotic metabolism and toxicity. Since FMO2 is primarily expressed in lung this will provide information on how 27% of African-Americans and 5% of Hispanics...
This paper addresses how the implementation of North American Free Trade Agreement (NAFTA) has affected the use of Information Technology (IT) in Mexico. In order to answer this question this thesis analyzes the direct and indirect effects of NAFTA on Mexico’s economic and regulatory environment, and how this influences the...
In the fall of 2005, I studied abroad in Athens, Greece for one term. This is retelling of experiences that I had, written in the style of my memories. While I was in Greece, I kept an electronic diary, a picture diary, and a scrapbook to keep my memories vivid...
America’s rural Hispanic population is growing at an unprecedented rate. Many of the Hispanic people that are settling in rural communities are immigrants or first generation Americans. If changes to current healthcare systems are required to accommodate the health needs of this growing, low-income rural population they have not been...
DNA mismatch repair (MMR) is an evolutionary conserved process that functions to maintain genomic integrity through the correction of mismatches that have escaped proofreading. Mutations in the MMR gene Mlh1 are associated with approximately 50% of all cases of Lynch syndrome, a hereditary predisposition to colorectal cancer, through varying and...
This project combines service learning with narrative writing (fiction and non-fiction) as an effective tool for the discovery and communication of social understanding; more specifically, the project discusses white privilege in literary form. Four short stories and seven vignettes, drawn from service learning experience over the course of three years,...
In order to combine my passion for creativity, my love for children, and my engineering background, I decided to create a very personalized thesis project. Princess Catie Goes to College is a children’s book about a young girl whose older sister leaves for college. I chose to write about this...
Our research was focused mainly on the field of plasma physics and the creation of plasmas in a laboratory environment. We first began our project with the goal to develop a tabletop Tokamak, a doughnut shaped device that magnetically confines plasmas at pressures greater than one atmosphere. After researching this...
Sickle cell disease (SCD) is a phenotypically variable disorder of hemoglobin that leads to abnormally shaped and dysfunctional red blood cells. Several studies have attempted to construct early predictive models for SCD, including Miller et al.’s (2000) model which uses easily identifiable predictors in early life. The primary aim of...
High-throughput culturing (HTC) consisting of extinction culturing in autoclaved seawater has led to the isolation and characterization of many novel strains of oligotrophic marine bacteria. Strain HTCC 2207 was isolated from the Oregon coast by the HTC method. Phylogenetic analysis based on 16S rRNA gene sequence showed that this strain...
This thesis explores a three month period that I spent abroad working in medical clinics and hospitals in Ecuador. My work was conducted in three distinct areas: the urban landscape of Quito, Ecuador’s capital; Puyo, a small town bordering the Amazonian rainforest; and a small community located in the heart...
The computer game industry continues to progress toward realistic-looking character motion. However, even in state-of-the-art games, the use of motion capture data in character animation may result in errors such as “foot slipping,” where the feet do not match up with the floor properly during translation. Various algorithms have been...
Wind energy is a cornerstone to the world of renewables. It is widely used in many parts of the world as a clean and effective form of power generation. However, wind power has a number of drawbacks, which limits its use in many regions. Solar power has been used not...
As time continues, the issue of full European Union membership for Norway becomes a more pertinent issue. The EU has long awaited the membership of Norway, but unfortunately the Nordic country has decided to remain independent. Norway’s historical past has led many Norwegians to believe their country is not ready...
The LIGO interferometers have reached their designed sensitivity level which is greater than any other interferometer ever built. At this point, it is important to have a proper understanding of small perturbations that might still exist (until now these issues did not come to the forefront because other more critical...
Through examination of empirical evidence on individuals with Asperger’s Syndrome and related Pervasive Developmental Disorders, the author attempts to provide an overview of the social deficiencies associated with these disorders. Points of primary concern are the social deficiencies in developing competence in experience-sharing and demonstrating empathy, especially in how they...
Two strains of Escherichia coli were studied to determine the effect of constitutive expression of the SOS DNA damage repair response on the activity of ribonucleotide reductase. Activity of the reductase and cellular deoxynucleoside triphosphate (dNTP) pools were both determined before and after exposure of the cells to ultraviolet radiation....
Prostate cancer is the most commonly diagnosed cancer in men, but rates around the world vary greatly. Americans have the highest incidence rates in the world, 4 to 5 times those of Spain. The hypothesis of this thesis was that vitamin D metabolism is a factor in prostate cancer development...
Celiac disease, an autoimmune response triggered by the consumption of seed storage proteins of cereals, affects an estimated 1% of the human population. In the case of wheat (Triticum aestivum L.), one of the world’s most consumed cereals, alcohol-soluble proteins, the gliadins, have been identified as the allergy-eliciting agents. Previous...
During the 1970’s the United States experienced several periods of high inflation that have been at least partially attributed to positive oil price shocks. The effectiveness of the Organization of Petroleum Exporting Countries at controlling the price of oil has varied over time, as well as the responsiveness of U.S....
Science is difficult for even its researchers to understand. Science journalists must understand scientific discoveries well enough to write clear, accurate explanations of scientific discoveries for laypeople. A sense of ethical judgment will help journalists ensure that their accounts are reliable and appropriate. Responsible science journalists will maintain a working...
Dental disease is a very prevalent and costly disease in which the symptoms, not the disease, are currently being treated. The disease is caused by pathogenic oral bacteria, many of which are a part of the Mutans Streptococci. The objective of this thesis was to find a natural substance that...
Mangroves are becoming increasingly recognized as important nursery habitats for many juvenile fish and macroinvertebrate species, however little is known about their importance for zooplankton communities. The complex structure of mangrove environments may provide zooplankton populations with shelter, substrate, food, and protection from depredation. These factors could impact zooplankton survival,...