Index Catalog // ScholarsArchive@OSU

Vernalization gene architecture as a predictor of growth habit in barley

Creator:: Heckart, Douglas
Abstract:: Winter hardiness in barley (Hordeum vulgare) is a trait targeted by breeding programs in order to expand the potential area of adaptation of fall-sown cereals. Vernalization requirement is an important factor in winter hardiness. A vernalization requirement is an extended period of low temperature required for transition from the vegetative...
Resource Type:: Undergraduate Thesis and Presentation

Characterization of a Sporulation-Specific Kinase in Clostridium perfringens

Creator:: Danielson, Bryan
Abstract:: Clostridium perfringens type A isolates produce the spore-specific enterotoxin, CPE, upon sporulation in the gastrointestinal tract of humans and animals. Spo0A is a response regulator representing the major transcription factor for sporulation initiation in C. perfringens. In Bacillus subtilis, a multicomponent phosphorelay involving five histidine kinases (KinA-KinE), the intermediate response...
Resource Type:: Undergraduate Thesis and Presentation

Method development in in vitro immune response

Creator:: Huber, Jacob
Abstract:: The AhR is a ligand-activated transcription factor that mediates the potent immunosuppressive effects of TCDD. AhR-dependent changes in gene expression appear to alter the differentiation of CD4+ T cells to induce a population of CD4+CD25+ T regulatory cells (Tregs) that suppress the immune response. Ascertaining if and how the AhR...
Resource Type:: Undergraduate Thesis and Presentation

Expression of prolactin in feline mammary adenomas and adenocarcinomas

Creator:: Trummel, Danielle K.
Abstract:: Mammary tumors are the third most common tumor in cats after cutaneous neoplasia and lymphosarcoma. More than 80% of feline mammary tumors are adenocarcinomas, which are similar to human mammary adenocarcinomas in their biologic behavior and histologic characteristics. Despite treatment with radical mastectomy, feline mammary adenocarcinoma is associated with a...
Resource Type:: Undergraduate Thesis and Presentation

Barley genetics as a model for international collaborative research

Creator:: Osborn, Lauren A.
Abstract:: Collaboration is crucial when advancing in scientific research. One person cannot study all aspects of a system. That is why it is important for the scientific community to communicate with each other and stay updated on research being conducted in other labs around the world. In my research, I was...
Resource Type:: Presentation and Honors College Thesis

Degradation of Extracellular Matrix Proteins by Bovine Embryonic Urokinase-Type Plasminogen Activator

Creator:: Hansen, Lance
Abstract:: The bovine blastocyst is composed of a one-celled layer of trophectoderm surrounding a fluid filled sac called the blastocoel and a ball of cells called the inner cell mass (ICM). On Day 8 (Day 0=fertilization) in bovine embryos, endodermal cells leave the ICM, migrate over the extracellular matrix (ECM) on...
Resource Type:: Undergraduate Thesis and Presentation

Developing the Zebrafish (Danio rerio) As a Model to Evaluate the Toxicity of Chlorinated and Non-Chlorinated Solvents

Creator:: Wenning, Matthew
Abstract:: Chlorinated and non-chlorinated solvents are used in a variety of industrial processes and as a consequence, they have become environmental contaminants as well. Because of this, they lead to both occupational and environmental exposures. Exposure to these compounds can potentially result in various forms of neurological damage with a wide...
Resource Type:: Undergraduate Thesis and Presentation

Use of sheep in the control of an invasive bunchgrass

Creator:: Scholz, Ryan
Abstract:: Studies were conducted to assess influencing the effectiveness of sheep for grazing control of false brome (Brachypodium sylvaticum) an invasive grass species. Orphan lambs were exposed to false brome via grass extract in their milk and naturally reared lambs were exposed by grazing dense stands of false brome with their...
Resource Type:: Undergraduate Thesis and Presentation

Potential of eradicating noxious weed seeds from the soil with heat and carabid seed predators

Creator:: Marshall, Nicole S.
Abstract:: The goal of this project was to develop and test non-herbicidal techniques that remove nonnative plant or weed seeds from the top 2 inches of the soil. The Nature Conservancy (TNC) is currently restoring prairies in the Willamette Valley. Some areas of the Pacific Northwest have already seen loss of...
Resource Type:: Undergraduate Thesis and Presentation

Effects of land management on carbon and nitrogen in soils from New Zealand

Creator:: Holcomb, Jess
Abstract:: The ability of soils to store large quantities of carbon (C) makes them an important factor in the global C cycle. Small changes within soil C can lead to large changes in atmospheric C. Land management practices can influence the amount of C that is stored within the soil and...
Resource Type:: Undergraduate Thesis and Presentation

Genetic variation of Renibacterium salmoninarum genes in infected salmonids

Creator:: Burnett, Jeffrey R.
Abstract:: Renibacterium salmoninarum is the causative agent of bacterial kidney disease in both wild and farmed salmonid species worldwide. The genome of this pathogen has significant synteny to the ubiquitous, soil-dwelling Arthrobacter spp. though it is 1.9 Mb smaller, suggesting that reductive evolution has occurred. Recently, our group finished sequencing and...
Resource Type:: Undergraduate Thesis and Presentation

The toxicogenetic effects of a chitosan based hemostatic control patch in rat models

Creator:: Colburn, Andrew J.
Abstract:: Chitosan based hemorrhage control dressings provide effective external hemorrhage control while having few side effects. Known residual contaminants present in chitosan formulations include endotoxins and proteins known to stimulate gene expression in the liver. This study investigated gene expression in the liver using rat bio-compatibility models to gain knowledge regarding...
Resource Type:: Undergraduate Thesis and Presentation

Superior Anti-tumor Activity Exhibited From a Gemcitabine Prodrug Incorporated into Lecithin-Based Nanoparticles

Creator:: Sandoval, Michael
Abstract:: Cancer is class of diseases that has great diversity and unfortunately is one of the leading causes of death in the United States. Chemotherapy remains an important cancer treatment modality, and superior chemotherapeutic drugs are constantly being sought. Gemcitabine is an anti-tumor chemotherapeutic drug and it is the first line...
Resource Type:: Poster, Undergraduate Thesis, and Presentation

Integration of embryonic zebrafish and passive sampling device extracts to explore effects of pesticide mixtures

Creator:: Corvi, Margaret
Abstract:: Pesticides are ubiquitous, with more than one billion tons of pesticide products used in the United States annually. These compounds are characterized by their toxic effects to the target organism; however, pesticides are also well known for their deleterious effects to non-target species. Because pesticides have ecological and human health...
Resource Type:: Undergraduate Thesis and Presentation

Immunohistochemistry Studies of Tumor Necrosis Factor Αlpha and Interferon Gamma Expression in Pseudocapillaria tomentosa Infected and Uninfected Zebrafish

Creator:: Lo, Lalee C.
Abstract:: Tumor necrosis factor alpha (TNF α) and interferon gamma (IFN γ) were initially recognized as inflammatory mediators produced by immune cells in response to infectious agents or foreign material. (1,5) However, over the past decade much research in mammalian species has indicated that these proteins also play key roles in...
Resource Type:: Presentation and Undergraduate Thesis

Effects of Perfluorinated Compounds on GnRH Gene Expression in vitro

Creator:: Bathke, Rebecca E.
Abstract:: Perfluorinated chemicals have been widely used in industry for their superior surfactant qualities. Because of their widespread usage and resistance to photolytic and biodegradation mechanisms, as well as their ability to undergo long-range atmospheric transport, these compounds have become ubiquitous in the world-wide water supplies. Of particular interest are perfluorooctanoic...
Resource Type:: Undergraduate Thesis and Presentation

Development of a colorimetric test kit to determine enzymatically produced pyruvic acid in sweet onions

Creator:: Merrill, Dawn C.
Abstract:: Sweet onions are valued for their unique flavor and praised for their health and dietary character. Onion sweetness is perceived as the degree of pungency decreases. Pungency can be quantitatively determined in onions by measuring enzymatically produced pyruvic acid. The onion industry quantifies a sweet onion as one having a...
Resource Type:: Undergraduate Thesis and Presentation

Use of Artemisinin to Treat Mycoplasma haemolama Infection in Llamas

Creator:: Puccetti, Jessica N.
Abstract:: Mycoplasma haemolamae is associated with mild to marked anemia in stressed, immune-suppressed, and debilitated animals, and may be found in low numbers in healthy animals. The continued presence of the organism, detectable by polymerase chain reaction (PCR)-based assay, may be associated with an underlying problem, such as stress or immune-suppression...
Resource Type:: Presentation

Developing Trap and Kill Technologies to Improve Management of the Western Spotted Cucumber Beetle (Diabrotica undecimpunctata undecimpunctata) and the Western Striped Cucumber Beetle (Acalymma trivittatum)

Creator:: Alderman, Katie
Abstract:: The western spotted cucumber beetle (Diabrotica undecimpunctata undecimpunctata) and the western striped cucumber beetle (Acalymma trivittatum) are pests of many crops, including vegetable, fruit, and nursery crops. Pesticides are commonly used to control this pest. Trap and kill technologies are under development as use in an alternative control for cucumber...
Resource Type:: Undergraduate Thesis and Presentation

Characterization of Type III Effectors from Pseudomonas syringae pv. tomato DC3000

Creator:: Thireault, Caitlin
Abstract:: Many Gram-negative bacteria use a type III secretion system (TTSS) to establish a relationship with a host. Pathogens can use the secretion system as a way to deliver proteins known as type III effectors (TTEs) into a host cell and block host defense. The variation and redundancy of the type...
Resource Type:: Undergraduate Thesis and Presentation

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