Polycyclic aromatic hydrocarbons (PAHs) are known to cause adverse health effects in the human lung. Here, we evaluated biomarkers relevant for PAH toxicity in a 3D human primary bronchial epithelial cell (HBEC) model collected from normal and asthmatic donors. We previously found that PAHs decrease cellular barrier function integrity, which...
Social discourse presents teenage childbearing as a “serious problem” that results in significant harm and expense to teenage mothers, their children, and society. Although the discourse of teenage childbearing has been multiple, overlapping, and contested, it has resulted in negative stereotyping and stigmatization of teenage mothers. Much of these stereotypes...
In the days following Oct. 5, 2007, the staff of The Daily Barometer - the student newspaper at Oregon State University - was left scrambling for understanding. The paper published a image of a man wearing black face paint for an event called "Blackout Reser." That black face paint looked...
During the end of a pet’s life its owner is often in emotional turmoil over how to feel and what to do. A veterinarian can alleviate some of this grief by effectively communicating during a terminal diagnosis and end-of-life discussion. Effective communication includes acknowledging the unique human-animal bond between client...
The nature of engineering work requires that ethical considerations are taken into account while making decisions surrounding topics such as technology, equal distribution of cost benefits, and consumer risk. In order for engineers to make ethical decisions in their careers, it is helpful if their engineering education provided them with...
There is increased emphasis on understanding cumulative risk from the combined effects of chemical and non-chemical stressors as it relates to public health. Recent animal studies have identified pulmonary inflammation as a possible modifier and risk factor for chemical toxicity in the lung after exposure to inhaled pollutants; however, little...
Mycoplasma haemolamae is associated with mild to marked anemia in stressed, immune-suppressed, and debilitated animals, and may be found in low numbers in healthy animals. The continued presence of the organism, detectable by polymerase chain reaction (PCR)-based assay, may be associated with an underlying problem, such as stress or immune-suppression...
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Susan J. Tornquist
Mycoplasma haemolamae is associated with mild to marked anemia in stressed
There is a growing need to establish alternative approaches for assessing hazard from chemical exposure compared to the traditional method of animal testing. Approaches that relate chemical structure to biological activity are gaining acceptance in the field as in silico methods for characterizing and predicting chemical toxicity. In this study,...
Phosphorodiamidate morpholino oligomers (PMOs) are novel antisense drugs in the early stages
of development. These synthetic DNA mimics contain the same bases found in DNA and anneal
to RNA in a complementary fashion. PMOs have been designed that target genes responsible for
producing essential proteins in organisms such as Escherichia...
Dibenzo[def,p]chrysene (DBC) is a highly potent, but less prevalent, environmental carcinogen belonging to a class of compounds known as Polycyclic Aromatic Hydrocarbons (PAHs). They are highly ubiquitous and arise as a byproduct of natural and anthropogenic combustion processes. Previous studies have documented carcinogenic effects upon in utero exposure of PAHs....