Chlamydia abortus, an intracellular bacterium, spreads through flocks of sheep and goats, causing ovine enzootic abortion (OAE). Chlamydiae develop within a pathogen-modified vacuole in the host cell called the inclusion, which allows the bacteria to acquire host resources. The morphology of the inclusion varies between chlamydial species. Some species fuse...
Over 100 years separate the 1918 Influenza and COVID-19 pandemics, and a multitude of science, public health and communication advancements have emerged. With the COVID-19 pandemic still underway, recently reaching the one million death mark in the United States alone (CDC, 2020), researchers are searching for clues as to how...
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Lauren Dalton, Committee Member, representing the Department of Biochemistry and
Biophysics
The Polycomb Repressive Complex 2 (PRC2) catalyzes genome transcription repression through the methylation of lysine residue 27 in the amino terminal region of histone 3 (H3K27me1/2/3) [2], [7]. PRC2 is made up of three highly conserved core subunits: Kmt6, Eed, and Suz12. Accurate distribution of PRC2 is essential for proper...
Carbon nanotubes are the subject of intense interest in virtually every field, from medicine to
nano-scale electrical components. Multi-walled nanotubes exhibit a strong nonlinear response
to high-field strength terahertz radiation. This research uses terahertz pulses with field strength
exceeding 1 MV/cm generated by means of optical rectification utilizing a lithium...
In recent years, tsunami events have caused great devastation and loss of life around the globe. The coast of Oregon is highly vulnerable to a nearfield tsunami event caused by a Cascadia Subduction Zone earthquake, yet lacks a clear plan for evacuation and disaster mitigation. Vertical evacuation is a proposed...
This thesis consists of two papers in manuscript format. The first paper presents optical measurements of tsunami inundation through an urban waterfront in a laboratory wave basin. The physical model was constructed at 1:50 scale and was an idealization of the town of Seaside, Oregon. The paper presents an analysis...
Variability in the depth and duration of anesthesia in individuals within a species is
frequently observed, yet few studies have investigated its causes in reptiles. To evaluate
the potential causes of variability in reptile anesthesia, I conducted experiments to test for
effects of body temperature, body composition and time post-feeding...
Although Latino students make up more than a quarter of the U.S. public school system, only three percent of children’s literature either features a Latino protagonist or is written by a Latino author (Machado et al.). Latinos are therefore severely underrepresented in children’s books. Additionally, studies have revealed that Latino...
Chlamydia possesses an immense importance within both human and animal medicine when looking at pathogens. Chlamydia trachomatis infections have been shown to affect both the eye and genital tracts in millions of humans and animals every year [13]. As C. trachomatis strains are highly conserved in patients, it has made...
Our laboratory is exploring the mechanism of action of a novel broad spectrum antiviral, ST-669. This compound has activity against a variety of different viruses and the obligate intracellular bacterium, Chlamydia. In this study, we explored the effects of ST-669 when the cell cycle of the host cells was altered....