Self-regulation is a cognitive mechanism that allows children to maintain control over their behaviors and emotions. The importance of this function is well-documented, but there is less understanding of the factors that affect children’s development of self-regulation. Therefore, the objective of this study is to examine if parent stress in...
Hemodynamic forces regulate vascular homeostasis and arterial structure through mechanical stimuli by a process called mechanotransduction. Cellular response to mechanical forces involves coordination between cell surface receptors and intracellular signaling pathways. While previous work has focused on the role of integrin receptors in mechanotransduction, little is known about the role...
The NKUA1 is a Small Fission Surface Power (SFSP) space reactor intended for use in upcoming missions to Mars and the moon between the years 2020-2030. The concept of the reactor was created by Dr. Lee Mason and his research team in a joint effort between the Department of Energy...
Oxygenated polycyclic aromatic hydrocarbons (OPAHs) are a class of environmentally prevalent compounds with little known information on their effect in vivo. In a recent study conducted using zebrafish as a model, 38 OPAHs were screened for toxicity. This investigation focuses on two of these OPAHs, 7,12-B[a]AQ and BEZO. Both 7,12-B[a]AQ...
Human epidermal growth factor receptor 2 (HER2), a member of the receptor tyrosine kinase (RTK) family, is frequently dysregulated in a variety of cancers. Overexpression of the receptor leads to increased cell proliferation and resistance to cell death due to downstream signaling effects. Proteasomal degradation of HER2 results in the...
Fluorescence spectroscopy is a powerful analytical technique due to bright signals that provide excellent measurement sensitivity. Many colors of fluorescent dyes are available to match the detection ranges of different equipments. Dyes can be chemically modified to bind to many different target analytes with high specificity1. Alternatively, sensors can be...
Respiratory Syncytial Virus (RSV) is a leading cause of bronchopneumonia in infants and elderly. Knowledge of viral and host protein interactions is important for better understanding of the viral pathogenesis and may lead to development of novel therapeutic drugs. Here, we show that RSV Matrix (M) protein interacts with cellular...