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Filtering by: Creator Filichkin, Sergei A. Remove constraint Creator: Filichkin, Sergei A. Degree Level Bachelor's Remove constraint Degree Level: Bachelor's

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  • Validation of Predicted Functional Transcription Factor Binding Sites in Arabidopsis thaliana

    Creator:
    Ozguc, Olivia R.
    Abstract:
    Gene expression is largely regulated by the binding of transcription factors to short sequences of DNA (transcription factor binding sites) to drive or repress transcription of an adjacent gene. Identifying the key transcription factor binding sites associated with a particular biological outcome provides an avenue for tailored transcriptional regulation in...
    Resource Type:
    Honors College Thesis
    Full Text:
    was built using data generated by Maria Ivanchenko and Sergei Filichkin, with algorithms implemented

  • Effects of Oxidative Stress on Circadian Gene Expression during Aging

    Creator:
    Bonar, Tara
    Abstract:
    All organisms possess circadian clocks, which generate daily oscillations in clock controlled gene expression that regulate many essential biological functions in synchrony with the 24-hour light/dark cycles. When the genes that control the internal clock are weakened, accelerated aging symptoms are observed. Past research in Drosophila demonstrated that aging flies...
    Resource Type:
    Honors College Thesis
    Full Text:
    Computer Science Sergei Filichkin, Committee Member, representing Department of Botany and Plant

  • Exploring Links between Circadian Rhythms and Healthy Aging

    Creator:
    Mattison, Braden J.
    Abstract:
    Circadian rhythms are the daily oscillations in multiple organism functions, from clock gene expression to behavior. Lost or irregular rhythms lead to health problems later in life including nervous system disorders, abnormal sleep/activity cycles, diabetes and obesity. However, it is not known whether strengthening the expression of clock genes throughout...
    Resource Type:
    Honors College Thesis
    Full Text:
    Member, representing Integrative Biology Sergei Filichkin, Committee Member, representing Botany and