Tuberculosis (TB) is a pressing global health issue with approximately one third of the world’s population infected by this bacterium. As one of the most dangerous infectious diseases, it has killed approximately 1.7 million people of all ages around the world per year (World Health Organization, 2016). Currently, several drugs...
Natural products from plants, bacteria, and fungi play an important role in society. Over the last 35 years, natural products and their derivatives have inspired over 60% of all FDA approved small-molecule drugs, and are among the top prescribed therapeutics.1-2 Fleming’s discovery of the fungal antibiotic penicillin started the “Golden...
With the rise of resistant bacterial pathogens, currently prescribed antibiotics are rendered useless. In recent years, marine natural products (MNPs) have emerged as novel sources for drug leads. The ocean is a complex environment where marine animals cohabitate with many, and sometimes harmful microorganisms and viruses, but resist infections. Developed...
Pseudomonas aeruginosa is a gram-negative nosocomial pathogenic bacterium known for its resilience against antibiotics. The bacterium infects over 50,000 patients each year in the United States, with 13% of reported cases involving multi-drug-resistant strains of Pseudomonas. This research discovered several fungal natural products with promising activity against Pseudomonas aeruginosa. The...
Endophytes, foliage inhabiting fungi, are an unexplored source of fungal biodiversity and a potential resource for the production of bioactive natural products. In this research, leaf tissues from the species Arbutus menziesii, Rhododendron macrophyllum and the genus, Ilex and Salix were collected for the isolation of endophytic fungi. Fungal extracts...
Rockfishes (Sebastes) are important species for commercial and recreational fishing, as well as evolutionary and ecological research. It can be impractical to identify the sex of rockfishes using visual identification or lethal dissection, and the sex-determination systems of these species have not been studied extensively. The aim of this research...
The 4.59-4.18 Ma Caspana ignimbrite, found within the Altiplano-Puna Volcanic Complex (APVC), is the result of an ~8km3 eruption that took place during the Neogene Ignimbrite Flare-up in the N. Chilean Andes. While most of the eruptions during this flare up are large, monogenetic eruptions, the Caspana that is characterized...
In the United States, the state of housing and the lack thereof has been
declared a national crisis. In response, cities have taken measures to police behaviors
that are associated with what they perceive to be disorder and decay. These behaviors
are also commonly associated with houselessness. Laws that criminalize...
Since the mid-nineteenth century, different waves of feminism have shaped a more fair, equitable world for women. Today, the fourth wave of feminism brings about a new initiative that focuses on menstruation. This traditionally taboo topic has formed failing policies that neglect the care, empowerment, and importance of women’s bodies,...
One of the roots of the global problem of HIV/AIDS is the shame associated with an HIV diagnosis. Because it can be transmitted sexually, HIV is stigmatized. Even though there are many routes of transmission that would not cause embarrassment, many times the public view is uncompassionate towards its victims,...