Local economic development can help lessen the impact of large-scale shocks on small communities as it provides them with resilient systems that do not require as much support from global supply chains. In smaller communities, shared governance, interactive and adaptive planning, and evidence-based policymaking strategies can facilitate resilient systems. The...
When iron levels are low, the opportunistic pathogen Pseudomonas aeruginosa secretes the high-affinity iron-binding siderophore pyoverdine. The cognate ferripyoverdine receptor, FpvA, has gained attention as the most divergent gene in the organism’s genome, showing substantial evidence of positive selection. S-type pyocins, bacteriocins with specificity to Pseudomonads, enter cells through FpvA...
Pseudomonas aeruginosa is a ubiquitous gram-negative bacterium that is capable of causing infections in people who are immune compromised. The bacterium can live in a variety of environments due to the variety of virulence factors it can produce. It is well adapted to living in iron-stringent conditions because it can...
While the quorum-sensing (QS) diversity of the opportunistic pathogen Pseudomonas aeruginosa has been well established in cystic fibrosis (CF) lung infections and in vitro experiments, little is known about its QS-diversity in natural environments. One significant QS-deficient behavior is social cheating. Social cheaters contain mutations that prevent them from producing...
The opportunistic pathogen Pseudomonas aeruginosa possesses two LuxR-LuxI
type quorum-sensing systems that use diffusible acyl-homoserine lactone molecules to
autoinduce and coordinate expression of multiple virulence factors. We conducted a highthroughput
screen for mutants deficient in skim-milk proteolysis—a quorum-sensing
dependent phenotype—using a nonredundant transposon-insertion library representing
most nonessential genes in P....
BoGL is a programming language created for the purpose of computer science education that is specific to the domain of board games. Although there is a language grammar and an existing implementation that is currently used by students, a complete and formal language standard does not yet exist. In the...
Over the last ten years, clinical, pre-clinical and animal studies have shown associations between the microbiota and neurological functions. Recent work by the scientific community on the gut-microbiome-brain axis have revealed that gut dysbiosis and specific microbial taxa are associated with a myriad of neurological conditions, such as autism spectrum...
This study looked at the impacts of climate change on medicinal plants, and how these impacts are viewed and understood in the herbalism community. Two literature reviews were conducted, to look at each of these two ideas: the first was a review of peer-reviewed literature describing research on climate change...
Vibrio parahaemolyticus, a naturally occurring halophilic pathogen, is seasonally abundant in marine and estuarine environments. It is also the leading cause of gastroenteritis in humans world-wide. Numerous outbreak incidences associated with the pathogenic Vibrio parahaemolyticus contaminations in oyster products have raised public-health concerns as well as economic challenges to the...