This thesis investigates lithogenic sediments on the Siberian Arctic shelf, their sources, modes of dispersal, transport pathways and post-depositional diagenetic alteration. Working with cores collected from the Chukchi, East Siberian and Laptev Seas, we characterize surface-sediment elemental chemistry and clay mineralogy. We identify five regions with endmember sedimentary compositions. Comparing...
Generally presented as a preferred social norm based on both ethical considerations and legislative demands, gender equality has been highly encouraged in recent years. For instance, The United Nations Sustainable Development Goals for 2030 call out achieving gender equality and empowerment of women. However, although there are multiple efforts to...
Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiquitously expressed, but is particularly enriched in skeletal and cardiac muscle tissue. Mutations covering the length of the protein have been linked to muscle wasting diseases including limb-girdle muscular dystrophy and Myoshi myopathy. Dysferlin has been shown to play...
Coral reefs have become vulnerable to climate change, with mass bleaching events, the loss of symbiotic algae (Symbiodiniaceae), increasing in both frequency and severity. As climate change continues to threaten the persistence and existence of coral reefs around the world, the biggest question posed for coral reefs is “can they...
Global increases in ultraviolet-B radiation (UVBR:290-
320 nm) resulting from decreases in stratospheric ozone
concentration have the potential to alter marine primary
production and affect global climate and marine trophic
dynamics. Effects of UVBR on phytoplankton carbon fixation
were determined from open ocean exposure studies conducted
off the coast of...
Auditory defects and disorders are prevalent at all ages and affect 8% of the population in developed nations including newborns and children. Congenital hearing loss is the most common birth defect and it is estimated that 1 in 1000 children are affected by deafness at birth or before the onset...
Distributed version control allows developers to manage software evolution among distributed development teams. But it does not eliminate all consistency and concurrency issues, and instead introduces additional complexity when merging code. And resolving merge conflicts is nontrivial when automated merging fails. In such cases, developers are forced to inspect the...
The goal of this dissertation was to improve our abilities in acquiring critical in vivo data by establishing embryo-larva zebrafish as an exemplary model to quantitatively evaluate cancer progression. The living environment that encompasses a tumor has a significant effect on how cancer develops, grows and metastasizes. In order to...
3D volume segmentation is a fundamental process in many scientific and medical applications. Producing accurate segmentations, in an efficient way, is challenging, in part due to low imaging data quality (e.g., noise and low image resolution), and ambiguity in the data that can only be resolved with higher-level knowledge of...
This thesis investigates the behavior of major inorganic nutrients (P, N, Si), trace metals (Mn, Fe), and alkaline-earth metals (Ba) within Tillamook Bay over seasonal cycles and under a range of river discharge conditions from October 1997 through December 1999. Located in the Pacific Northwest region, Tillamook Bay is an...