Index Catalog // ScholarsArchive@OSU

A new technique for high performance tandem time-of-flight mass spectrometry

Creator:: Katz, Daniel Louis
Abstract:: The main result of this written dissertation is a mathematical solution to the problem of multiplex recording for high performance tandem time-of-flight mass spectrometry. The prescription is to use a time-lag accelerator in the second stage to match the ion optical properties of the decay fragments to the requirements of...
Resource Type:: Dissertation
Full Text:: Technique for High Performance Tandem Time-of-Flight Mass Spectrometry. Abstract approved. Douglas F

Time-of-flight scattering and recoil spectrometry (TOF-SARS) applied to molecular liquid surfaces : a new approach to surface composition and orientation

Creator:: Gannon, Thomas J.
Abstract:: In spite of their importance in many systems, liquid surfaces have been explored at the microscopic level to a much lesser extent than solids. Most surface analysis must take place in vacuum, a major drawback for liquids. The technique of time-of-flight scattering and recoil spectrometry (TOF-SARS) has been applied to...
Resource Type:: Dissertation
Full Text:: technique of time-of-flight scattering and recoil spectrometry (TOF-SARS) has been applied to molecular

Time-of-flight direct recoil spectrometry : application to liquid surfaces and steps toward quantification

Creator:: Tassotto, Michael
Abstract:: Liquid surfaces are very abundant in nature. Despite the importance of the liquid interface in general, experimental molecular-level data was almost completely lacking prior to the last decade and a half. The intent of this work is to provide a means by which experimental data on the composition of liquid...
Resource Type:: Dissertation
Full Text:: basic idea is identical to the one exploited in time-of-flight secondary ion mass spectrometry (TOP

Development and broad application of a mass spectrometry based metabolomics platform

Creator:: Kirkwood, Jay Steven
Abstract:: Metabolomics is a comprehensive analysis of small molecules, or metabolites, in a system. Metabolomics is a hypothesis-generating experiment and offers an unbiased analysis of cell metabolism that can aid in the understanding of fundamental biological processes. Metabolomics is widely and broadly applicable in the biological sciences and has been used...
Resource Type:: Dissertation
Full Text:: chromatography-quadrupole-time-of-flight mass spectrometry metabolomics platform and details the various steps

The identification and quantitation of complex polycyclic aromatic hydrocarbon mixtures in environmental samples using comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry

Creator:: Manzano, Carlos A.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous contaminants and are mostly products of the incomplete combustion of organic material. PAHs are often found in environmental samples as a complex mixture of isomers. In addition, the same sources that produce complex PAH mixtures also produce other poorly characterized mixtures of organic compounds,...
Resource Type:: Dissertation
Full Text:: Chromatography with Time-of-flight Mass Spectrometry Abstract approved: Staci L. Massey Simonich

Surface composition and orientation of room temperature ionic liquids

Creator:: Law, George
Abstract:: In this thesis, we investigated the surface composition and orientation of both pure room-temperature ionic liquids (Ils) and binary mixtures of the ILs of the type consisting of the 1-alkyl-3-methylimidazolium ([C[subscropt n]mim]⁺, n=4, 8, and 12) cation coupled with either [PF₆]⁻, [BF₄]⁻, [Cl]⁻, or [Br]⁻. The surfaces of the ILs...
Resource Type:: Dissertation
Full Text:: and recoiling spectrometry (TOF-SARS), and time-of-flight direct recoil spectrometry (TOF-DRS). The

Analysis of electrophilic compounds using an electron monochromator : mass spectrometer system

Creator:: Mazurkiewicz, Paul H.
Resource Type:: Dissertation
Full Text:: seconds) in comparison to the time of flight of an ion from the ion source to the detector of the mass

Characterization of UV-crosslinked protein-nucleic acid interfaces by Maldi MS and ESI MS/MS

Creator:: Gafken, Philip R.
Resource Type:: Dissertation
Full Text:: MALDI MS AnaJysis of hRPA7O x dT30 Nucleopeptides ......... 181 6.1.8 Tandem Mass Spectrometry of

Mass-Spectrometric Methods for OxPTM Characterization and Quantitative Proteomics of Oxidative Stress Response

Creator:: Huang, Lin
Abstract:: Oxidative stress is deﬁned as an imbalance that favors the production of reactive oxygen species (ROS) over an organism's antioxidant defense. ROS have the ability to damage, either directly or indirectly, biomolecules including DNA, proteins, carbohydrates, and lipids. Various pathological conditions and environmental and chronic diseases have been associated with...
Resource Type:: Dissertation
Full Text:: memory. Firstly, we explored the applicability of travelling wave ion mobility mass spectrometry

Alkylation of peptides and proteins by S-(2-chloroethyl)glutathione and characterization of adducts by mass spectrometry

Creator:: Erve, John C. L.
Abstract:: Glutathione, a ubiquitous intracellular tripeptide, protects cells by reacting with electrophiles and radicals that can damage cellular macromolecules. However, glutathione conjugation is now recognized as one mechanism by which drugs and xenobiotics can also be converted to reactive intermediates having toxic consequences to cells. The halogenated alkane 1,2-dichloroethane forms S-(2-chloroethyl)...
Resource Type:: Dissertation
Full Text:: ultraviolet (Beavis and Chait, 1990). Time of flight mass spectrometers are the ideal mass analyzers when

ScholarsArchive@OSU

A new technique for high performance tandem time-of-flight mass spectrometry

Time-of-flight scattering and recoil spectrometry (TOF-SARS) applied to molecular liquid surfaces : a new approach to surface composition and orientation

Time-of-flight direct recoil spectrometry : application to liquid surfaces and steps toward quantification

Development and broad application of a mass spectrometry based metabolomics platform

The identification and quantitation of complex polycyclic aromatic hydrocarbon mixtures in environmental samples using comprehensive two-dimensional gas chromatography with time-of-flight mass spectrometry

Surface composition and orientation of room temperature ionic liquids

Analysis of electrophilic compounds using an electron monochromator : mass spectrometer system

Characterization of UV-crosslinked protein-nucleic acid interfaces by Maldi MS and ESI MS/MS

Mass-Spectrometric Methods for OxPTM Characterization and Quantitative Proteomics of Oxidative Stress Response

Alkylation of peptides and proteins by S-(2-chloroethyl)glutathione and characterization of adducts by mass spectrometry

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