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Bacterial 16S ribosomal DNA analysis of pyrrolizidine alkaloid detoxifying enrichments from the ovine rumen

Creator:: Gray, Diane R.
Abstract:: Bacterial cultures enriched from sheep rumen fluid have demonstrated the ability to detoxify pyrrolizidine alkaloids (seneciphylline and jacobine) in tansy ragwort (Senecio jacobaea). The microbes are difficult to isolate using classical anaerobic techniques, therefore, microbes from two different enrichment cultures demonstrating similar degradation activity were identified using their 16S ribosomal...
Resource Type:: Masters Thesis

Carcinogenicity and acute toxicity of dimethylnitrosamine in rainbow trout (Salmo gairdneri)

Creator:: Grieco, Mary Porter
Abstract:: A dose related carcinogenic response was established for dimethylnitrosamine administered in the diet of rainbow trout (Salmo gairdneri). An equation was derived for the relationship between dose and hepatocellular carcinoma incidence. From a published dose response study using Porton rats as a test animal, a second equation was derived for...
Resource Type:: Masters Thesis
Full Text:: Food Toxicology and Nutrition Laboratory is gratefully acknowledged. Thanks are also due to Gregory

A study of chronic Senecio jacobaea toxicosis in calves and ponies

Creator:: Pearson, Erwin G.
Abstract:: An experiment was designed to simulate field conditions of tansy ragwort poisoning in cattle and horses. Four calves and four ponies were fed pelleted feed containing 5% Senecio jacobaea and two ponies and two calves were used as controls. The feeding continued for two months. Following this, the chronic delayed...
Resource Type:: Masters Thesis

Determination of the transfer of pyrrolizidine alkaloids into goats milk by biological assay

Creator:: Goeger, Douglas Eugene
Resource Type:: Masters Thesis
Full Text:: chromatograms of S. jacobaea and S. glabellus alkaloid preparations. Alkaloid peaks designated by letters are

Induction of autoantibodies in MRL/lpr mice exposed to 2% aniline denatured low-erucic acid rapeseed oil, an oil associated with the Spanish Toxic Oil Syndrome

Creator:: Richards, Carolyn L. K.
Abstract:: In 1981, illegal processing of rapeseed oil by a Spanish oil refinery resulted in the mass foodborne illness epidemic known as Toxic Oil Syndrome (TOS). The toxic oil associated with this epidemic was sold in neighborhood markets and by itinerant salesmen as inexpensive olive oil. Ingestion of the toxic oil...
Resource Type:: Masters Thesis

Sulfide metabolism in Lucina floridana, a sulfur symbiont-containing marine clam

Creator:: Larabee, Jeannine Kay
Abstract:: Lucina floridana is an intertidal clam that contains intracellular, sulfur-oxidizing symbiotic bacteria in its gills. These bacteria are chemolithoautotrophic, using the energy from the oxidation of reduced sulfur compounds to power carbon fixation. Although sulfide is an energy-rich compound, it is also toxic to aerobic metabolism and autooxidizes in the...
Resource Type:: Masters Thesis
Full Text:: with different letters are significantly different from each other (P < 0.01). See text for

Antimutagenic potency of wheat grain and berry extracts in vitro and anticarcinogenicity of wheat grain in vivo

Creator:: Yu, Zhen
Abstract:: The antimutagenic potency of wheat grain and berry extracts was studied in vitro against several heterocyclic amines (HCAs) using the Salmonella mutagenicity assay and the anticarcinogencity of wheat grain was studied in vivo using the rat colonic aberrant crypt focus assay. Wheat bran, which binds HCAs in vitro, as well...
Resource Type:: Masters Thesis
Full Text:: of Science in Toxicology presented on October 15. 2002. Title: Antimutagenic Potency of Wheat Grain

Size and surface area dependent toxicity of silver nanoparticles in zebrafish embryos (Danio rerio)

Creator:: Tuttle, George R.
Abstract:: Many studies addressing the toxicity of silver nanomaterials have found that smaller sized silver nanoparticles are usually more toxic to organisms and in cell culture than particles of larger sizes yet it is not entirely clear why. We investigated the size dependent toxicity of silver nanoparticles by measuring the response...
Resource Type:: Masters Thesis
Full Text:: ) AN ABSTRACT OF THE THESIS OF George R. Tuttle for the degree of Master of Science in Toxicology

Effects of chlorinated aliphatic hydrocarbon degradation on the metabolic enzymes in Nitrosomonas europaea

Creator:: Fawcett, Kimberly A.
Abstract:: The toxic effects of degrading the chlorinated hydrocarbons trichloroethylene (TCE), chloroform (CF) and cis-1,2-dichloroethylene (cis-1,2-DCE) were studied in the bacterium Nitrosomonas europaea. N europaea is an ammonia-oxidizing bacterium that obtains all of its energy from the oxidation of ammonia to nitrite. This metabolic process involves two enzymes, ammonia monooxygenase (AMO)...
Resource Type:: Masters Thesis
Full Text:: the degree of Masters of Science in Toxicology presented on January 12th, 1999. Title: Effects of

Evaluation of current agricultural practices and organophosphorus insecticide use in relation to ring-necked pheasant numbers at Klamath Basin Refuges, California

Creator:: Grove, Robert Allan
Abstract:: A declining population of ring-necked pheasants (Phasianus colchicus) was studied at Tule Lake National Wildlife Refuge (TLNWR) from the summer of 1990 through the spring of 1993. Pheasant densities/50 ha at TLNWR in 1989, 1991, and 1992 were considerably lower (16.86, 8.49, and 6.81) than the >62 density seen in...
Resource Type:: Masters Thesis
Full Text:: AN ABSTRACT OF THE THESIS OF Robert Allan Grove for the degree of Master of Science in Toxicology

ScholarsArchive@OSU

Bacterial 16S ribosomal DNA analysis of pyrrolizidine alkaloid detoxifying enrichments from the ovine rumen

Carcinogenicity and acute toxicity of dimethylnitrosamine in rainbow trout (Salmo gairdneri)

A study of chronic Senecio jacobaea toxicosis in calves and ponies

Determination of the transfer of pyrrolizidine alkaloids into goats milk by biological assay

Induction of autoantibodies in MRL/lpr mice exposed to 2% aniline denatured low-erucic acid rapeseed oil, an oil associated with the Spanish Toxic Oil Syndrome

Sulfide metabolism in Lucina floridana, a sulfur symbiont-containing marine clam

Antimutagenic potency of wheat grain and berry extracts in vitro and anticarcinogenicity of wheat grain in vivo

Size and surface area dependent toxicity of silver nanoparticles in zebrafish embryos (Danio rerio)

Effects of chlorinated aliphatic hydrocarbon degradation on the metabolic enzymes in Nitrosomonas europaea

Evaluation of current agricultural practices and organophosphorus insecticide use in relation to ring-necked pheasant numbers at Klamath Basin Refuges, California

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