Index Catalog // ScholarsArchive@OSU

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

Creator:: Ding, Jun
Abstract:: The studies described in this thesis were motivated by ongoing efforts to develop lignocellulosic biomass as an efficient and practical source of renewable energy. Enormous problems complicate these efforts to reduce reliance on greenhouse gas-generating fossil fuels. Simply obtaining the fermentable sugars available in the cellulose and hemicellulose components of...
Resource Type:: Dissertation
Full Text:: cerevisiae Abstract approved: Alan T. Bakalinsky The studies described in this thesis

A study of antimutagenicity in yogurt

Creator:: Sudarshan, Nadathur R.
Abstract:: The purpose of this study was to identify antimutagens in yogurt active against the experimental colon carcinogen, N-methyl-N'-nitro-N-nitrosoguanidine (MNNG). Our initial experiments showed that acetone extracts of yogurt, or milk fermented by various lactic acid bacteria were antimutagenic against MNNG and 3,2'-dimethyl-4-aminobiphenyl (DMAB) in the Ames test (Salmonella typhimurium TA...
Resource Type:: Dissertation
Full Text:: Antimutagenicity in Yogurt Abstract Approved: ^ Alan T. Bakalinsky The purpose of this study was to identify

Applied and basic aspects of sulfite metabolism in Saccharomyces cerevisiae

Creator:: Park, Hoon
Abstract:: In an effort to understand the basis for sulfite detoxification in S. cerevisiae, the functions of two genes were analyzed. SSU1, which encodes a plasma membrane protein, was found to be required for efficient sulfite efflux. FZFl-4, a dominant allele of a transcriptional activator of SSUl, was also found to...
Resource Type:: Dissertation
Full Text:: Aspects of Sulfite Metabolism in Saccharomyces cerevisiae. Abstract approved: Alan T. Bakalinsky

Genetic aspects of sulfite tolerance in Saccharomyces cerevisiae

Creator:: Avram, Dorina
Resource Type:: Dissertation
Full Text:: Abstract approved: Alan T. Bakalinsky Sulfite is a normal, but potentially toxic metabolite, in S

Biomarkers of oxidative stress and DNA damage in agricultural workers

Creator:: Muniz, Juan Fermin
Abstract:: Pesticides are among the most pervasive environmental contaminants and they are an important potential risk for human health. Agricultural workers are constantly exposed to pesticide spray, drift and residues in the soil and foliage. Many agricultural pesticides are readily absorbed by the body, through contact with the skin, the respiratory...
Resource Type:: Dissertation
Full Text:: University, and Alan T. Bakalinsky, Ph.D. Associate Professor, Food Science and Technology and a Graduate

Investigation of the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity in C57B1/6 mice : effects on T cell activation

Creator:: Prell, Rodney A.
Resource Type:: Dissertation
Full Text:: of 2,3,7,8-tetrachlorodibenzo-p- dioxin-Induced Immunotoxicity in C57B1/6 Mice: Effects on T Cell

Metabolism of one carbon (C1) and methylated compounds in SAR11 bacteria

Creator:: Sun, Jing
Abstract:: SAR11 Alphaproteobacteria are the most abundant aerobic chemoheterotrophs in ocean surface waters. Previous studies have indicated SAR11 cells play an important role in marine carbon cycling and consume up to half of some common dissolved organic compounds, such as amino acids. During sequencing of the first SAR11 genome, genes for...
Resource Type:: Dissertation
Full Text:: , Dr. Mark E. Dolan, Dr. Alan T. Bakalinsky and Dr. Katja Duesterdieck-Zellmer for their broad

Development and broad application of a mass spectrometry based metabolomics platform

Creator:: Kirkwood, Jay Steven
Abstract:: Metabolomics is a comprehensive analysis of small molecules, or metabolites, in a system. Metabolomics is a hypothesis-generating experiment and offers an unbiased analysis of cell metabolism that can aid in the understanding of fundamental biological processes. Metabolomics is widely and broadly applicable in the biological sciences and has been used...
Resource Type:: Dissertation
Full Text:: ......................................................................................49 Zebrafish α-T, AA, uric acid, and MDA concentrations ...........................49

Unraveling the endogenous functions of the aryl hydrocarbon receptor (AHR) and characterizing a novel long non-coding RNA (slincR) that contributes to AHR-mediated toxic responses in zebrafish

Creator:: Garcia, Gloria R.
Abstract:: The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor that is a member of the basic helix-loop-helix PER-ARNT-SIM (bHLH/PAS) protein family of cellular sensors. The AHR is conserved across multiple animal phyla and is required for proper vertebrate development. A structurally diverse group of chemicals, including polycyclic aromatic...
Resource Type:: Dissertation
Full Text:: signal derived from SV40 Large T Ag (Clonetech; Mountain View, CA) were injected into the cell of a one

Exploring the cellular mechanisms of Cnidarian bleaching in the sea anemone Aiptasia pallida

Creator:: Perez, Santiago
Abstract:: Many members of the Phylum Cnidaria are mutualistic with unicellular dinoflagellates belonging to the genus Symbiodinium. Corals are the most widely recognized example of these associations due to their key ecological importance in coral reef ecosystems where they serve as the structural and trophic foundation of these rich ecosystems. Coral...
Resource Type:: Dissertation
Full Text:: hardships. I thank my committee, Lynda Ciuffetti, Daniel Rockey, Dahong Zhang and Alan Bakalinsky for

ScholarsArchive@OSU

In vivo detoxification of acetic acid in Saccharomyces cerevisiae

A study of antimutagenicity in yogurt

Applied and basic aspects of sulfite metabolism in Saccharomyces cerevisiae

Genetic aspects of sulfite tolerance in Saccharomyces cerevisiae

Biomarkers of oxidative stress and DNA damage in agricultural workers

Investigation of the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity in C57B1/6 mice : effects on T cell activation

Metabolism of one carbon (C1) and methylated compounds in SAR11 bacteria

Development and broad application of a mass spectrometry based metabolomics platform

Unraveling the endogenous functions of the aryl hydrocarbon receptor (AHR) and characterizing a novel long non-coding RNA (slincR) that contributes to AHR-mediated toxic responses in zebrafish

Exploring the cellular mechanisms of Cnidarian bleaching in the sea anemone Aiptasia pallida

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