Index Catalog // ScholarsArchive@OSU

Investigating the effects of harvest time and light exposure on cannabinoid potency in industrial hemp (Cannabis sativa) using UPLC-diode array detection

Creator:: Saindon, Ashley L.
Abstract:: Five varieties of industrial hemp (Cannabis sativa) were grown in the field in Imperial Valley, CA, USA in order to determine whether light conditions or harvest times influence cannabinoid content. A total of 16 cannabinoids were investigated in this study: Delta-9-tetrahydrocannibinol (THC-d9), Delta-9-tetrahydrocannibinolic acid (THC-a), Cannabidiol (CBD), Cannabidiolic acid (CBD-a),...
Resource Type:: Honors College Thesis
Full Text:: Duringer, Mentor, representing the Department of Environmental and Molecular Toxicology

Molecular origins of peptide entrapment within polyethylene oxide brush layers

Creator:: Lampi, Marsha C.
Abstract:: Effective surface coatings for tissue-contacting medical devices should prevent both biofilm formation and infection. One method to achieve this aim is protein repellant polyethylene oxide (PEO) brush coatings loaded with antimicrobials. Previous research has demonstrated that the antimicrobial nisin adsorbs to PEO brush layers in multi-layer amounts and suggests that...
Resource Type:: Honors College Thesis
Full Text:: , 2012. Title: Molecular origins of peptide entrapment within polyethylene oxide brush layers

High Resolution Spectroscopy of Bicyclo[1.1.1]pentane

Creator:: Martin, Matthew A.
Abstract:: The strained carbon ring, bicyclo[1.1.1]pentane, was synthesized by a reaction between 1-(phenylsulfanyl)bicyclo[1.1.1]pentane, prepared from propellane, and Raney nickel. Infrared spectra were recorded at a resolution of 0.0015 cm-1, a resolution significantly better than previous measurements, 0.06 cm-1. A single fundamental band was analyzed to determine the ground state and excited...
Resource Type:: Honors College Thesis
Full Text:: Chemistry presented on May 29, 2009. Title: High Resolution Spectroscopy of Bicyclo[1.1.1]pentane

Surface composition age analysis of photo-oxidized polystyrene thin films by X-ray photoelectron spectroscopy

Creator:: Silva, Nicholas A.
Abstract:: Polystyrene thin film surfaces are commonly used to study the interactions of macromolecules, such as proteins, with surfaces. Polystyrene films oxidized in UV light become more hydrophilic, however these surfaces have a limited shelf life because they are reduced over time. Experiments were performed to determine the effect of radiation...
Resource Type:: Honors College Thesis
Full Text:: FIlms by X-ray Photoelectron Spectroscopy 1 AN ABSTRACT OF THE THESIS OF Nicholas A. Silva

Molecular Origins of Recombinant Factor VIII (rFVIII)

Creator:: Tadehara, Katherine M.
Abstract:: The capability of Pluronic® F68 to stabilize human recombinant Factor VIII in solution was assessed using zeta potential measurements. Hemophilia A is a genetic disorder in which the body is missing Factor VIII (FVIII) from the blood coagulation cascade. The pharmaceutical industry developed recombinant Factor VIII (rFVIII), the largest cloned...
Resource Type:: Honors College Thesis
Full Text:: Molecular Origins of Recombinant Factor VIII (rFVIII) Stabilization with Pluronic® F68 By

Second Derivative Excitation Emission Resolution (SEC DEER) Spectroscopy

Creator:: Rosene, Benjamin L.
Abstract:: Fluorescence spectroscopy is a powerful analytical technique due to bright signals that provide excellent measurement sensitivity. Many colors of fluorescent dyes are available to match the detection ranges of different equipments. Dyes can be chemically modified to bind to many different target analytes with high specificity1. Alternatively, sensors can be...
Resource Type:: Honors College Thesis
Full Text:: Optical Resolution Spectroscopy, or STORM. They created bimolecular complexes with one of three well

Stability of Super Folder Green Fluorescent Protein Under Varying Organic Solvent and Temperature Conditions

Creator:: Ho, Lylan
Abstract:: Obtaining high-resolution structures of biological macromolecules has become one of the biggest challenges in the scientific world. Dr. Wei Kong’s lab is currently working to overcome the limitations of current structure resolution techniques, such as x-ray crystallography and nuclear magnetic resonance spectroscopy. Kong’s group hopes to develop a new protein...
Resource Type:: Honors College Thesis
Full Text:: Science in Biochemistry and Molecular Biology presented on May 31, 2019. Title: Stability of Super

A (3-Aminopropyl)triethoxysilane (APTES) and Glutaraldehyde Functionalized Cellulose Surface for Immunoassays

Creator:: Harley, William
Abstract:: The detection of biomolecules is critical for clinical diagnostics but requires specialty labor and high cost. The use of microfluidic paper-based analytical devices (µPADs) for bioassays is simpler and cheaper but has low sensitivity. Improved immobilization of antibodies onto cellulose is demonstrated through surface functionalization with APTES and glutaraldehyde. The...
Resource Type:: Honors College Thesis
Full Text:: FTIR Spectroscopy for Their Further Implementation to Building Materials. American Journal of

Differential Binding and Structural Properties of the WWC Protein Family

Creator:: Rodriguez, Diego Javier
Abstract:: The WWC family consists of three proteins‐ KIBRA/WWC1, WWC2, and WWC3. The three proteins share a similar primary structure and interact with a common set of proteins. Each paralog contains two WW domains which recognize proline‐rich sequences of the type PPxY (P is proline, Y is tyrosine, x is any...
Resource Type:: Honors College Thesis
Full Text:: requirements for the degrees of Honors Baccalaureate of Science in Biochemistry and Molecular

Catalysis of Biologically Relevant Chlorination Reactions by Nicotine, and Potential Relevance to Tissue Damage

Creator:: Dolan, Brigh G.
Abstract:: This work is concerned with determining whether nicotine has a role in promoting oxidative damage in human tissue, particularly in lung tissue. This follows from recent reports of a novel lung disease found in some E-cigarette users, characterized by oxidative damage and elevated levels of neutrophils (termed “vaping disease”). It...
Resource Type:: Honors College Thesis
Full Text:: Dolan for the degree of Honors Baccalaureate of Science in Biochemistry and Molecular Biology

ScholarsArchive@OSU

Investigating the effects of harvest time and light exposure on cannabinoid potency in industrial hemp (Cannabis sativa) using UPLC-diode array detection

Molecular origins of peptide entrapment within polyethylene oxide brush layers

High Resolution Spectroscopy of Bicyclo[1.1.1]pentane

Surface composition age analysis of photo-oxidized polystyrene thin films by X-ray photoelectron spectroscopy

Molecular Origins of Recombinant Factor VIII (rFVIII)

Second Derivative Excitation Emission Resolution (SEC DEER) Spectroscopy

Stability of Super Folder Green Fluorescent Protein Under Varying Organic Solvent and Temperature Conditions

A (3-Aminopropyl)triethoxysilane (APTES) and Glutaraldehyde Functionalized Cellulose Surface for Immunoassays

Differential Binding and Structural Properties of the WWC Protein Family

Catalysis of Biologically Relevant Chlorination Reactions by Nicotine, and Potential Relevance to Tissue Damage

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