Index Catalog // ScholarsArchive@OSU

Chandler Loop Model for the Development of Dynamic Hemocompatibility Assays

Creator:: Hasbrook, AnneMarie V.
Abstract:: A common issue with extracorporeal medical devices is blood clotting due to bio-incompatibility. Systemic anticoagulants are often prescribed to mitigate the coagulation issues. However, such drugs can lead to further complications, for example hemorrhaging. One solution to improve the hemocompatibility of blood-contacting medical devices are biomaterials, such as slippery liquid...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Adam Z. Higgins, Committee Member, representing Bioengineering

Investigating the Potential for Cryopreservation of Human Granulocytes with Concentrated Glycerol

Creator:: Moss, Alden C.
Abstract:: Granulocytes are a class of white blood cells essential to immune function. Granulocyte transfusions hold promise to treat many conditions, but the short-shelf life of granulocytes makes transfusions infeasible without a cell preservation method. The purpose of this study was to investigate the potential for cryopreservation of granulocytes using 30%...
Resource Type:: Honors College Thesis
Full Text:: Glycerol C o n c . (O s m /k g ) Glycerol Removal Step 1: dilute 1:10 in 1.0 molal glycerol

Novel Predictive Simulation of Organ Perfusion Kinetics for Design of Cryopreservation Procedures

Creator:: Johnson, Hill S.
Abstract:: Despite the many advances in biotechnology and biomedical engineering, the need for long term organ and tissue storage remains among the unsolved problems in the field. Researchers are investigating several possible solutions to the issue that aim to maintain the function and integrity of the biological tissues during storage and...
Resource Type:: Honors College Thesis
Full Text:: Adam Z Higgins, representing College of Chemical, Biological, and Environmental Engineering

Detection and Segmentation of Bird Song in Noisy Environments

Creator:: Neal, Lawrence W.
Abstract:: Recent work in machine learning concerns the detection and identification of bird species from audio recordings of their vocalizations. Such analysis can yield valuable ecological information concerning the activity and distribution of species in the wild. Current species-identification methods require individual syllables of bird audio as input, but field-collected audio...
Resource Type:: Honors College Thesis
Full Text:: and Segmentation of Bird Song in Noisy Environments Abstract approved: Xiaoli Z. Fern Recent work

The Effects of Toxicity Inhibitors on the Cytotoxicity of Cryoprotective Agents using a High-Throughput Experimental Set-up

Creator:: Ampo, Emi
Abstract:: Even with advanced medical technology, there is still an unmet need for organs to reduce the transplant waiting list and to advance organ-related research. Cryopreservation through vitrification is one possible solution to increase organ availability. A major challenge with cryopreservation of organs is the toxicity of the cryoprotectants (CPAs) that...
Resource Type:: Honors College Thesis
Full Text:: . APPROVED: _____________________________________________________________________ Adam Z

The Effect of HSA and Hematocrit on the Cake Collapse Temperature of Lyophilized Red Blood Cells

Creator:: Runyon, Daniel E.
Abstract:: Freeze-drying, or lyophilization, has shown great promise in addressing many of the logistical challenges of storing and preserving red blood cells (RBCs). A crucial part of any future RBC lyophilization protocol is the primary drying temperature, which affects the sample drying rate and the dried cake’s ability to form a...
Resource Type:: Honors College Thesis
Full Text:: Cells. Abstract approved: ____________________________________________________________ Adam Z

“Narco-Deforestation” in Central American Protected Areas: Developing A Spatiotemporal Proxy Database for Drug-Trafficking Activities from Media Reporting

Creator:: Cameron, Olivia Z.
Abstract:: On a global scale, illicit economies have dramatic impacts on the physical environment. Cocaine trafficking has been recognized as a major driver of deforestation inside Central American protected areas. A key problem in studying and managing the environmental impacts of illicit economic activity is the difficulty in obtaining reliable data....
Resource Type:: Honors College Thesis
Full Text:: ., Richani, N., Pearson, Z., Devine, J., & Wrathall, D. J. (2017). Why Do Narcos Invest in Rural Land

Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor (RhoGDI) Ly-GDI in platelet function

Creator:: Thierheimer, Marisa
Abstract:: Platelets undergo morphological changes essential to hemostasis upon activation at sites of vascular injury. The Rho GTPases Rac1, Cdc42, and RhoA drive these changes. Rho guanine nucleotide dissociation inhibitors (RhoGDIs) bind to the Rho GTPases to block the GDP from dissociating from the Rho GTPases, as well as anchoring the...
Resource Type:: Honors College Thesis
Full Text:: contain one site of N-glycosylation. The GPVI tail contains a proline‐rich region that recruits Src

Ink and Substrate Compatibility for Electrochemical Sensing in Paper-based Devices

Creator:: Reid, Caitlin A.
Abstract:: Electrochemical sensing provides a quantitative alternative to colorimetric reactions within paper-based devices. The paper-based devices were fabricated by screen printing the conductive and reference inks onto porous substrates that were evaluated using cyclic voltammetry. Devices were evaluated based on the magnitude of the average anodic peak height, which correlates with...
Resource Type:: Honors College Thesis
Full Text:: . = 0.4462𝑛𝐹𝐴𝐶 7 𝑛𝐹𝑣𝐷 𝑅𝑇 < = > Where ip = current (amps), n = number of electrons transferred in the

Hibernation Strategies to Improve Organ Preservation and Storage

Creator:: Engler, Maja T.
Abstract:: Looking to the natural world for insight into medical innovations is currently understudied and possibly underappreciated in the field of medicine. Natural environmental adaptations seen in wild animals can provide both inspiration and scientific realization for the future of human medicine. As humanity faces a global organ shortage crisis, research...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Adam Z. Higgins, Committee Member, representing Chemical, Biological, and Environmental

ScholarsArchive@OSU

Chandler Loop Model for the Development of Dynamic Hemocompatibility Assays

Investigating the Potential for Cryopreservation of Human Granulocytes with Concentrated Glycerol

Novel Predictive Simulation of Organ Perfusion Kinetics for Design of Cryopreservation Procedures

Detection and Segmentation of Bird Song in Noisy Environments

The Effects of Toxicity Inhibitors on the Cytotoxicity of Cryoprotective Agents using a High-Throughput Experimental Set-up

The Effect of HSA and Hematocrit on the Cake Collapse Temperature of Lyophilized Red Blood Cells

“Narco-Deforestation” in Central American Protected Areas: Developing A Spatiotemporal Proxy Database for Drug-Trafficking Activities from Media Reporting

Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor (RhoGDI) Ly-GDI in platelet function

Ink and Substrate Compatibility for Electrochemical Sensing in Paper-based Devices

Hibernation Strategies to Improve Organ Preservation and Storage

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