Index Catalog // ScholarsArchive@OSU

The Effect of HSA and Hematocrit on the Cake Collapse Temperature of Lyophilized Red Blood Cells

Creator:: Runyon, Daniel E.
Abstract:: Freeze-drying, or lyophilization, has shown great promise in addressing many of the logistical challenges of storing and preserving red blood cells (RBCs). A crucial part of any future RBC lyophilization protocol is the primary drying temperature, which affects the sample drying rate and the dried cake’s ability to form a...
Resource Type:: Honors College Thesis
Full Text:: Cells. Abstract approved: ____________________________________________________________ Adam Z

Novel Predictive Simulation of Organ Perfusion Kinetics for Design of Cryopreservation Procedures

Creator:: Johnson, Hill S.
Abstract:: Despite the many advances in biotechnology and biomedical engineering, the need for long term organ and tissue storage remains among the unsolved problems in the field. Researchers are investigating several possible solutions to the issue that aim to maintain the function and integrity of the biological tissues during storage and...
Resource Type:: Honors College Thesis
Full Text:: Adam Z Higgins, representing College of Chemical, Biological, and Environmental Engineering

E+A galaxy and spiral E+A galaxy candidates in the Hercules supercluster

Creator:: Williams, Rosemary H.
Abstract:: E+A galaxies represent an important niche in galaxy evolution as a subset of post-starburst galaxies. Set apart from other post-starburst galaxies by their rapid quenching of star formation, E+As are thought to have started their formation outside a galaxy cluster's center and have fallen inward due to gravity; the star...
Resource Type:: Honors College Thesis
Full Text:: Liu E+A galaxies represent an important niche in galaxy evolution as a subset of post

Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor (RhoGDI) Ly-GDI in platelet function

Creator:: Thierheimer, Marisa
Abstract:: Platelets undergo morphological changes essential to hemostasis upon activation at sites of vascular injury. The Rho GTPases Rac1, Cdc42, and RhoA drive these changes. Rho guanine nucleotide dissociation inhibitors (RhoGDIs) bind to the Rho GTPases to block the GDP from dissociating from the Rho GTPases, as well as anchoring the...
Resource Type:: Honors College Thesis

Ink and Substrate Compatibility for Electrochemical Sensing in Paper-based Devices

Creator:: Reid, Caitlin A.
Abstract:: Electrochemical sensing provides a quantitative alternative to colorimetric reactions within paper-based devices. The paper-based devices were fabricated by screen printing the conductive and reference inks onto porous substrates that were evaluated using cyclic voltammetry. Devices were evaluated based on the magnitude of the average anodic peak height, which correlates with...
Resource Type:: Honors College Thesis

Limit Equilibrium-Based Assessment of the Internal Stability of Geosynthetic Reinforced Soil Structures Subject to Seismicity

Creator:: Loving, Carly K.
Abstract:: Design of Geosynthetic-Reinforced Soil Structures (GRSS) require sufficient rear pullout anchoring capacity in order to maintain internal stability. Length requirements are amplified when reinforcement coverage ratios or seismicity is considered, potentially resulting in uneconomical GRSS design lengths. This study describes the influence of reinforcement length, coverage ratio, and pseudostatic seismic...
Resource Type:: Honors College Thesis
Full Text:: _____________________________________________________________________ Judy Liu, Committee Member, representing Structural Engineering

Differences in expression of COVID-19 related inflammatory genes in non-human primates with varying alcohol consumption

Creator:: Co, Amber
Abstract:: Severe cases of COVID-19 have been associated with cytokine storms, leading to widespread inflammation, tissue damage, and organ failure. Pro-inflammatory cytokines have also been shown to play a role in liver diseases, including alcoholic liver disease. To investigate alcohol consumption as a risk factor for SARS-CoV-2 infections and COVID-19 severity,...
Resource Type:: Honors College Thesis
Full Text:: , Zhang Y, Huang S, Liu Z, Cheng J. (2020). Clinical Features of COVID-19-Related Liver Functional

The Generation of a Zebrafish Microbial Culture Collection to Facilitate Mechanistic Understanding of Host-Microbe Interactions

Creator:: VanderHoek, Zoe K.
Abstract:: A rapidly expanding body of evidence suggests that relationships exist between the microbiome and vertebrate health and disease. The zebrafish is a frequently utilized model organism to support this claim. Specifically, its gut microbiome is an advantageous resource for the study of microbiome health and diversity. While it is an...
Resource Type:: Honors College Thesis
Full Text:: behind observable phenomena (Liu et al., 2020). Additionally, specific taxa may be identified from

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks.

Creator:: Choudhury, Mudra
Abstract:: While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...
Resource Type:: Honors College Thesis
Full Text:: enzyme Ubc13. Nat Commun 5:5798. doi: 10.1038/ncomms6798 42. Peng X-P, Huang L, Liu Z-H (2016) miRNA

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks

Creator:: Choudhury, Mudra
Abstract:: While monocytes are vital for host defense against pathogens, in cases of non-resolving inflammation, monocytes and their differentiated progeny can secrete tissue-damaging factors, present auto-antigens, and promote the inflammatory response. In this study, a systems biology approach was used to map human monocyte gene regulatory regions by integrating expression quantitative...
Resource Type:: Honors College Thesis
Full Text:: enzyme Ubc13. Nat Commun 5:5798. doi: 10.1038/ncomms6798 42. Peng X-P, Huang L, Liu Z-H (2016) miRNA

ScholarsArchive@OSU

The Effect of HSA and Hematocrit on the Cake Collapse Temperature of Lyophilized Red Blood Cells

Novel Predictive Simulation of Organ Perfusion Kinetics for Design of Cryopreservation Procedures

E+A galaxy and spiral E+A galaxy candidates in the Hercules supercluster

Assessment of roles for the Rho-specific guanine nucleotide dissociation inhibitor (RhoGDI) Ly-GDI in platelet function

Ink and Substrate Compatibility for Electrochemical Sensing in Paper-based Devices

Limit Equilibrium-Based Assessment of the Internal Stability of Geosynthetic Reinforced Soil Structures Subject to Seismicity

Differences in expression of COVID-19 related inflammatory genes in non-human primates with varying alcohol consumption

The Generation of a Zebrafish Microbial Culture Collection to Facilitate Mechanistic Understanding of Host-Microbe Interactions

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks.

The Development and Application of a Systems Biology Approach to Mapping Monocyte Gene Regulatory Networks

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