Index Catalog // ScholarsArchive@OSU

Comparison and optimization of chromatographic conditions for separation of cyclic dynorphin A analogues from linear byproducts

Creator:: Leelasvatanakij, Leena
Resource Type:: Masters Thesis
Full Text:: . Thirdly, I would like to acknowledge my committee members, Dr. Michael W. Schuyler, Dr. T. Mark Zabriskie

Biosynthetic studies of fungal diterpene antibiotics

Creator:: Yao, Qingmei
Abstract:: The isoprenoid pathway is one of the major biosynthetic pathways of secondary metabolites. Isoprenoids with a C₂₀ skeleton are known as diterpenoids and are derived from the common precursor, geranylgeranyl diphosphate (GGPP). This dissertation describes approaches to discover the diterpene synthase enzymes which provide the backbone structures for pleuromutilin and...
Resource Type:: Masters Thesis
Full Text:: , guidance, and patience in this research project and dissertation. I would also like to thank Dr. T. Mark

Synthesis and opioid activity of dynorphin analogues with the modifications in the message sequence

Creator:: Kulkarni, Sandhya N.
Resource Type:: Masters Thesis
Full Text:: members, Dr. Douglas Barofsky, Dr. Mark Zabriskie and Dr. Markle Douglas. I appreciate the cooperation

Effects of quinolinate and nitro-, or thio- substituted analogs of quinolinate on glutamate receptor-mediated neurotoxicity in cerebellar granule cell cultures

Creator:: Zhang, Jinying
Abstract:: Quinolinate (QUIN) is an endogenous neurotoxic product of the kynurenine pathway of tryptophan metabolism. Quinolinate is a selective agonist of the NMDA family of glutamate receptors and, as such, may play a role in the pathology of a number of major central nervous system (CNS) disorders. These include both chronic...
Resource Type:: Masters Thesis
Full Text:: possible. I owe my deepest gratitude to Dr. Mark Zabriskie and Ms. Hua Qi for their work supplying me

Biosynthesis studies and mutasynthesis of myxobacterial secondary metabolites

Creator:: Knight, Eva W.
Abstract:: Myxobacteria represent an interesting class of Gram-negative soil bacteria. These bacteria utilize organic materials from the environment as a food source by the action of their extracellular hydrolytic enzymes. They grow vegetatively in the presence of adequate nutrients. During starvation conditions, however, they aggregate and form multicellular structures called fruiting...
Resource Type:: Masters Thesis
Full Text:: a NRPS-like A-T didomain at the N-terminus of the erythromycin PKS [26, 27]. In the current study

Novel secondary metabolites from a Madagascar collection of Lyngbya majuscula

Creator:: Nannini, Christopher J.
Abstract:: Marine organisms produce a variety of secondary metabolites for defense, communication, and reproduction. While these uses are essential for the organisms' survival, marine natural products have demonstrated their value to human society as well. Asian countries used algae for centuries to treat or prevent illnesses as wide-ranging as cough, gout,...
Resource Type:: Masters Thesis
Full Text:: Oregon State University. I graciously thank the members of my graduate committee, Dr. Mark Zabriskie

Development and testing of novel anti-tubercular drugs

Creator:: Almabruk, Khaled Husain G.
Abstract:: Tuberculoѕiѕ (TB) iѕ a number one killer among treatable infectious diseases. It is caused by the pathogenic bacterium Mycobacterium tuberculoѕiѕ that primarily affects the lungѕ. It infects one third of the world population and kills approximately 2 million people each year (based on WHO report). Drug-reѕiѕtant TB haѕ become a...
Resource Type:: Masters Thesis
Full Text:: . I would like to thank my graduate committee members, Dr. Mark Zabriskie, Dr. Jane Ishmael, Dr

Recent periglacial debris flows from Mount Rainier, Washington

Creator:: Copeland, Elizabeth A.
Abstract:: Debris flow initiation is controlled by a complex interaction of geology, geomorphology, climate, and weather. In the Cascade Range of Pacific Northwest and mountainous areas globally, patterns of temperature and precipitation are being altered by climate change, which may in turn impact debris flow initiation. Temperature has increased and patterns...
Resource Type:: Masters Thesis
Full Text:: facilitated by Arnie Peterson, Darin Swinney, Bret Cristo, and Barbara Semora, and Mark Meyers. Review

Immobilization of Methylosinus trichosporium OB3b in a Biolamina Plate Reactor for the Oxidation of Methane to Methanol

Creator:: Fuchs, Brian K.
Abstract:: Methane is a flammable gas that is the main component of natural gas. It is a highly potent greenhouse gas, and accounts for about 20% of greenhouse gas emissions. Methane is routinely flared in many industrial processes without harnessing any of its energy. The environmental impact and wasted energy potential...
Resource Type:: Masters Thesis
Full Text:: experiments. Dr. Goran Jovanovic, Dr. Lew Semprini, and Dr. Mark Dolan all provided leadership on the

Refrigerated seawater depuration for reducing Vibrio parahaemolyticus contamination in raw Pacific oysters (Crassostrea gigas)

Creator:: Yang, Qianru
Abstract:: Vibrio parahaemolyticus is a seafood-borne pathogen that can cause gastroenteritis in humans. This study investigated the effectiveness of refrigerated seawater (5°C) depuration on reducing V. parahaemolyticus in raw Pacific oysters (Crassostrea gigas). Raw Pacific oysters were inoculated with a mixed culture of five clinical strains of V. parahaemolyticus and depurated...
Resource Type:: Masters Thesis

ScholarsArchive@OSU

Comparison and optimization of chromatographic conditions for separation of cyclic dynorphin A analogues from linear byproducts

Biosynthetic studies of fungal diterpene antibiotics

Synthesis and opioid activity of dynorphin analogues with the modifications in the message sequence

Effects of quinolinate and nitro-, or thio- substituted analogs of quinolinate on glutamate receptor-mediated neurotoxicity in cerebellar granule cell cultures

Biosynthesis studies and mutasynthesis of myxobacterial secondary metabolites

Novel secondary metabolites from a Madagascar collection of Lyngbya majuscula

Development and testing of novel anti-tubercular drugs

Recent periglacial debris flows from Mount Rainier, Washington

Immobilization of Methylosinus trichosporium OB3b in a Biolamina Plate Reactor for the Oxidation of Methane to Methanol

Refrigerated seawater depuration for reducing Vibrio parahaemolyticus contamination in raw Pacific oysters (Crassostrea gigas)

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