This thesis details my investigation of some pharmaceuticals and natural products on the transport of drugs which are substrates of P-glycoprotein (P-gp), such as cyclosporin A (CSA) and digoxin by using Caco-2 and MDCKII-MDR1 drug transport models. Three objectives were performed to address this goal. The first objective was to...
This is a listing of both PhD and Master's· theses relating to the areas of forestry issued during the period from July 1976 to June 1981. The
list is arranged first by state, then by college or university within each state. Authors of theses are arranged alphabetically under each of...
Interspecific hybridization was initiated between wild P. acutifolius accession G40199 and P. vulgaris to introgress resistance to Acanthoscelides obtectus (bean seed weevil). F1 interspecific hybrids were recovered by embryo rescue and maintained until flowering. Mostly sterile hybrids were backcrossed twice to common bean cultivar ICA Pijao to recover sufficient fertility...
White mold, caused by Sclerotinia sclerotiorum (Lib.) de Bary, results in severe losses in the production of common bean, Phaseolus vulgaris, especially snap bean varieties. Advanced backcross QTL analysis was used to identify quantitative trait loci for resistance to white mold in an interspecific cross of P. vulgaris and P....
Recently, there has been concern over the decline of the Pacific lamprey, Lampetra tridentata, in the northwestern United States. However, effective management has been impeded by data gaps in basic biology, especially in the early life stages. Consequently, in 2004 and 2005 I examined reproductive ecology, larval recruitment, and lamprey...
One in four Ecuadorians do not have access to health services; while more than two-thirds have no health insurance and insufficient resources to pay for the health care services they might require. The following three studies examined utilization of health care services using Andersen’s Health Care Utilization Behavior Theory. Secondary...
Small broomrape (Orobanche minor) is an obligate, chlorophyll-lacking parasite that parasitizes red clover (Trifolium pratense) roots. This study was conducted to develop and implement an integrated, biologically based control program for small broomrape by using wheat as a false host to reduce the soil seed bank. The relationship between temperature...
The purpose of this essay is to explore the dynamics of social movements, and better understand why some populations succeed when others fail. This topic was motivated by travels across the United States and Europe. In these journeys, minority groups and their unequal treatment by society were a constant feature,...
The Chlamydiaceae are a family of obligate intracellular bacteria with a unique biphasic developmental cycle. The replicating, metabolically active, intracellular phase bacteria (RBs) grow within a cellular vacuole know as the inclusion. Since the proteins the Chlamydiaceae secrete into this membrane are the means of host/parasite interaction, they have long...