Index Catalog // ScholarsArchive@OSU

Regulation of Motility of Myogenic Cells in Filling Limb Muscle Anlagen by Pitx2

Creator:: Campbell, Adam L., Shih, Hung-Ping, Xu, Jun, Gross, Michael K., and Kioussi, Chrissa
Abstract:: Cells of the ventrolateral dermomyotome delaminate and migrate into the limb buds where they give rise to all muscles of the limbs. The migratory cells proliferate and form myoblasts, which withdraw from the cell cycle to become terminally differentiated myocytes. The myogenic lineage colonizes pre-patterned regions to form muscle anlagen...
Resource Type:: Article
Full Text:: cytoskeletal and adhesion molecules. Citation: Campbell AL, Shih H-P, Xu J, Gross MK, Kioussi C (2012

Loss of Abdominal Muscle in Pitx2 Mutants Associated with Altered Axial Specification of Lateral Plate Mesoderm

Creator:: Eng, Diana, Ma, Hsiao-Yen, Xu, Jun, Shih, Hung-Ping, Gross, Michael K., and Kiouss, Chrissa
Abstract:: Correction 17 Oct 2012: Eng D, Ma HY, Xu J, Shih HP, Gross MK, et al. (2012) Correction: Loss of Abdominal Muscle in Pitx2 Mutants Associated with Altered Axial Specification of Lateral Plate Mesoderm. PLOS ONE 7(10): 10.1371/annotation/c980d5a1-1899-4d30-af7b-573d4049cf4b
Resource Type:: Article
Full Text:: may be viewed either as lineage restriction or specification. Citation: Eng D, Ma H-Y, Xu J, Shih H-P

Population-Specific Regulation of Chmp2b by Lbx1 during Onset of Synaptogenesis in Lateral Association Interneurons

Creator:: Xu, Jun, Nonogaki, Mariko, Madhira, Ravi, Ma, Hsiao-Yen, Hermanson, Ola, Kioussi, Chrissa, and Gross, Michael K.
Abstract:: Chmp2b is closely related to Vps2, a key component of the yeast protein complex that creates the intralumenal vesicles of multivesicular bodies. Dominant negative mutations in Chmp2b cause autophagosome accumulation and neurodegenerative disease. Loss of Chmp2b causes failure of dendritic spine maturation in cultured neurons. The homeobox gene Lbx1 plays...
Resource Type:: Article
Full Text:: establish the disynaptic cutaneous reflex only between particular cell populations. Citation: Xu J

Preliminary Genomic Characterization of Ten Hardwood Tree Species from Multiplexed Low Coverage Whole Genome Sequencing

Creator:: Staton, Margaret, Best, Teodora, Khodwekar, Sudhir, Owusu, Sandra, Xu, Tao, Xu, Yi, Jennings, Tara, Cronn, Richard, Arumuganathan, A. Kathiravetpilla, Coggeshall, Mark, Gailing, Oliver, Liang, Haiying, Romero-Severson, Jeanne, Schlarbaum, Scott, and Carlson, John E.
Abstract:: Forest health issues are on the rise in the United States, resulting from introduction of alien pests and diseases, coupled with abiotic stresses related to climate change. Increasingly, forest scientists are finding genetic/genomic resources valuable in addressing forest health issues. For a set of ten ecologically and economically important native...
Resource Type:: Article
Full Text:: ., Best, T., Khodwekar, S., Owusu, S., Xu, T., Xu, Y., ... & Carlson, J. E. (2015). Preliminary Genomic

Novel Pactamycin Analogs Induce p53 Dependent Cell-Cycle Arrest at S-Phase in Human Head and Neck Squamous Cell Carcinoma (HNSCC) Cells

Creator:: Guha, Gunjan, Lu, Wanli, Li, Shan, Liang, Xiaobo, Kulesz-Martin, Molly F., Mahmud, Taifo, Indra, Arup Kumar, and Ganguli-Indra, Gitali
Abstract:: Pactamycin, although putatively touted as a potent antitumor agent, has never been used as an anticancer drug due to its high cytotoxicity. In this study, we characterized the effects of two novel biosynthetically engineered analogs of pactamycin, de-6MSA-7-demethyl-7- deoxypactamycin (TM-025) and 7-demethyl-7-deoxypactamycin (TM-026), in head and neck squamous cell carcinoma...
Resource Type:: Article
Full Text:: Carcinoma (HNSCC) Cells Guha, G., Lu, W., Li, S., Liang, X., Kulesz-Martin, M. F., Mahmud, T

Circadian Regulation of Glutathione Levels and Biosynthesis in Drosophila melanogaster

Creator:: Beaver, Laura M., Klichko, Vladimir I., Chow, Eileen S., Kotwica-Rolinska, Joanna, Williamson, Marisa, Orr, William C., Radyuk, Svetlana N., and Giebultowicz, Jadwiga M.
Abstract:: Circadian clocks generate daily rhythms in neuronal, physiological, and metabolic functions. Previous studies in mammals reported daily fluctuations in levels of the major endogenous antioxidant, glutathione (GSH), but the molecular mechanisms that govern such fluctuations remained unknown. To address this question, we used the model species Drosophila, which has a...
Resource Type:: Article
Full Text:: 4: e6469. 14. Xu K, Zheng X, Sehgal A (2008) Regulation of feeding and metabolism by neuronal and

Mechanistic Insights into Validoxylamine A 7’-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex

Creator:: Cavalier, Michael C., Yim, Young-Sun, Asamizu, Shumpei, Neau, David, Almabruk, Khaled H., Mahmud, Taifo, and Lee, Yong-Hwan
Abstract:: The pseudo-glycosyltransferase VldE catalyzes non-glycosidic C-N coupling between an unsaturated cyclitol and a saturated aminocyclitol with the conservation of the stereochemical configuration of the substrates to form validoxylamine A 7'-phosphate, the biosynthetic precursor of the antibiotic validamycin A. To study the molecular basis of its mechanism, the three-dimensional structures of...
Resource Type:: Article
Full Text:: (2010) Exploring genomes for glycosyltransferases. Mol Biosyst 6: 1773–1781. 2. Bai L, Li L, Xu H

Selenium and Selenoprotein Deficiencies Induce Widespread Pyogranuloma Formation in Mice, while High Levels of Dietary Selenium Decrease Liver Tumor Size Driven by TGFα

Creator:: Moustafa, Mohamed E., Carlson, Bradley A., Anver, Miriam R., Bobe, Gerd, Zhong, Nianxin, Ward, Jerrold M., Perella, Christine M., Hoffmann, Victoria J., Rogers, Keith, Combs, Gerald F., Jr., Schweizer, Ulrich, Merlino, Glenn, Gladyshev, Vadim N., and Hatfield, Dolph L.
Abstract:: Changes in dietary selenium and selenoprotein status may influence both anti- and pro-cancer pathways, making the outcome of interventions different from one study to another. To characterize such outcomes in a defined setting, we undertook a controlled hepatocarcinogenesis study involving varying levels of dietary selenium and altered selenoprotein status using...
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Full Text:: e - In ci d e n ce b M u lt ip li ci ty c G e n o ty p e G ro u p # M ic e in w h

The α-Tocopherol Transfer Protein Is Essential for Vertebrate Embryogenesis

Creator:: Miller, Galen W., Ulatowski, Lynn, Labut, Edwin M., Lebold, Katie M., Manor, Danny, Atkinson, Jeffrey, Barton, Carrie L., Tanguay, Robert L., and Traber, Maret G.
Abstract:: The hepatic α-tocopherol transfer protein (TTP) is required for optimal α-tocopherol bioavailability in humans; mutations in the human TTPA gene result in the heritable disorder ataxia with vitamin E deficiency (AVED, OMIM #277460). TTP is also expressed in mammalian uterine and placental cells and in the human embryonic yolk-sac, underscoring...
Resource Type:: Article
Full Text:: . Development 139: 2009–2019. 38. Li Z, Wang Y, Zhang M, Xu P, Huang H, et al. (2012) The Amotl2 gene inhibits

First Detection of the Larval Chalkbrood Disease Pathogen Ascosphaera apis (Ascomycota: Eurotiomycetes: Ascosphaerales) in Adult Bumble Bees

Creator:: Maxfield-Taylor, Sarah A., Mujic, Alija B., and Rao, Sujaya
Abstract:: Fungi in the genus Ascosphaera (Ascomycota: Eurotiomycetes: Ascosphaerales) cause chalkbrood disease in larvae of bees. Here, we report the first-ever detection of the fungus in adult bumble bees that were raised in captivity for studies on colony development. Wild queens of Bombus griseocollis, B. nevadensis and B. vosnesenskii were collected...
Resource Type:: Article
Full Text:: . FEMSMicrobiol Lett. 2012; 330: 17–22. doi: 10.1111/j.1574-6968.2012. 02515.x PMID: 22309373 27. Wubie AJ, Xu S

ScholarsArchive@OSU

Regulation of Motility of Myogenic Cells in Filling Limb Muscle Anlagen by Pitx2

Loss of Abdominal Muscle in Pitx2 Mutants Associated with Altered Axial Specification of Lateral Plate Mesoderm

Population-Specific Regulation of Chmp2b by Lbx1 during Onset of Synaptogenesis in Lateral Association Interneurons

Preliminary Genomic Characterization of Ten Hardwood Tree Species from Multiplexed Low Coverage Whole Genome Sequencing

Novel Pactamycin Analogs Induce p53 Dependent Cell-Cycle Arrest at S-Phase in Human Head and Neck Squamous Cell Carcinoma (HNSCC) Cells

Circadian Regulation of Glutathione Levels and Biosynthesis in Drosophila melanogaster

Mechanistic Insights into Validoxylamine A 7’-Phosphate Synthesis by VldE Using the Structure of the Entire Product Complex

Selenium and Selenoprotein Deficiencies Induce Widespread Pyogranuloma Formation in Mice, while High Levels of Dietary Selenium Decrease Liver Tumor Size Driven by TGFα

The α-Tocopherol Transfer Protein Is Essential for Vertebrate Embryogenesis

First Detection of the Larval Chalkbrood Disease Pathogen Ascosphaera apis (Ascomycota: Eurotiomycetes: Ascosphaerales) in Adult Bumble Bees

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