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  • The changes they are a-timed: metabolism, endogenousclocks, and the timing of puberty

    Creator:
    Tolson, Kristen P. and Chappell, Patrick E.
    Abstract:
    Childhood obesity has increased dramatically over the last several decades, particularly in industrialized countries, often accompanied by acceleration of pubertal progression and associated reproductive abnormalities (Biro et al., 2006; Rosenfield et al., 2009). The timing of pubertal initiation and progression in mammals is likely influenced by nutritional and metabolic state,...
    Resource Type:
    Article
    Full Text:
    clocks, and the timing of puberty REVIEW ARTICLE published: 28 March 2012 doi: 10.3389/fendo