Index Catalog // ScholarsArchive@OSU

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Creator:: Maxwell, Joseph R.
Abstract:: T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
Resource Type:: Dissertation
Full Text:: Costimulation and Adjuvants in the Development of T Cell Effector and Memory Responses. Abstract approved

Investigation of the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity in C57B1/6 mice : effects on T cell activation

Creator:: Prell, Rodney A.
Resource Type:: Dissertation
Full Text:: of 2,3,7,8-tetrachlorodibenzo-p- dioxin-Induced Immunotoxicity in C57B1/6 Mice: Effects on T Cell

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell activation

Creator:: Shepherd, David M.
Abstract:: The immune system has been identified as a very sensitive target for the toxic effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin (TCDD). Exposure to TCDD has been shown to disrupt the generation of both cell-mediated and humoral T cell-dependent immunity in laboratory animals; however, the mechanism remains unknown. In this dissertation, the hypothesis is...
Resource Type:: Dissertation
Full Text:: The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell

The influence of aryl hydrocarbon receptor activation on T cell fate

Creator:: Funatake, Castle J.
Abstract:: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds are well-recognized for their immunosuppressive activity, which is mediated through an intracellular receptor and transcription factor, aryl hydrocarbon receptor (AhR). Laboratory animals exposed to TCDD are less resistant to infection and have severely impaired humoral and cell-mediated immune responses. This dissertation addressed the hypothesis that...
Resource Type:: Dissertation
Full Text:: Hydrocarbon Receptor Activation on T Cell Fate. approved: 2,3,7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) and

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on Staphylococcal Enterotoxin B(SEB)-induced alterations in T-cell activation and cytokine production

Creator:: Huang, Wentian
Resource Type:: Dissertation
Full Text:: -Tetrachlorodibenzo-p-dioxin (TCDD) on Staphylococcal Enterotoxin B (SEB)-Induced Alterations in T-Cell Activation

T lymphocyte death as a potential mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immune suppression

Creator:: Dearstyne, Erica A.
Resource Type:: Dissertation
Full Text:: suppressive effects of TCDD. Exposure to TCDD causes a reduction in T cell numbers and function by unknown

Investigation of the mechanism of 3,3',4,4',5,5'-hexachlorobiphenyl-induced suppression of cytotoxic T lymphocyte activity in C57B1/6 mice : endocrine and cytokine dysregulation

Creator:: DeKrey, Gregory K.
Resource Type:: Dissertation
Full Text:: interleukin-2 and interferon-7 are impor tant for T cell proliferation and CTL maturation, these results

Uncovering the mechanism of IL-4-mediated T cell survival

Creator:: Moscibrocki, Cathleen M.
Abstract:: Although IL-4 is a well-characterized multi-functional cytokine, its role as a survival factor in T cells is not completely understood. In an attempt to uncover IL-4-mediated survival, we studied caspase activation in primary mouse T lymphocytes undergoing death by neglect, activation-induced or steroid-induced cell death. Here, we identify the executioner...
Resource Type:: Masters Thesis
Full Text:: of IL-4-mediated T Cell Survival. Abstract approved: Anthony T. Vella Although IL-4 is a well

Investigations of T cell costimulation and autoimmunity in mice, and development of flow cytometric methods to assess lymphocyte stimulation in dogs

Creator:: Weatherill, Amy R.
Abstract:: Proper immune function is indispensable, as failure to mount an immune response against a pathogen can lead to serious complications or even death. T cells act by enhancing the activation of phagocytic cells as well as the activation of B cells. Their widespread influence on an immune response makes optimal...
Resource Type:: Dissertation
Full Text:: of Doctor of Philosophy in Microbiology presented on April 25. 2002. Title: Investigations of T cell

Investigations of regulatory T cell induction by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin during a graft-versus-host response

Creator:: Marshall, Nikki B.
Abstract:: The immune toxicity of 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) has been studied for over 35 years, but only recently has the profound immune suppression associated with TCDD exposure been linked to induction of regulatory T cells (Tregs). The effects of TCDD are mediated through binding the aryl hydrocarbon receptor (AhR), a ligand-activated transcription...
Resource Type:: Dissertation
Full Text:: Microbiology presented on December 1, 2009. Title: Investigations of Regulatory T cell Induction by 2, 3, 7

ScholarsArchive@OSU

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Investigation of the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity in C57B1/6 mice : effects on T cell activation

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell activation

The influence of aryl hydrocarbon receptor activation on T cell fate

Effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) on Staphylococcal Enterotoxin B(SEB)-induced alterations in T-cell activation and cytokine production

T lymphocyte death as a potential mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD)-induced immune suppression

Investigation of the mechanism of 3,3',4,4',5,5'-hexachlorobiphenyl-induced suppression of cytotoxic T lymphocyte activity in C57B1/6 mice : endocrine and cytokine dysregulation

Uncovering the mechanism of IL-4-mediated T cell survival

Investigations of T cell costimulation and autoimmunity in mice, and development of flow cytometric methods to assess lymphocyte stimulation in dogs

Investigations of regulatory T cell induction by 2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin during a graft-versus-host response

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