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Filtering by: Advisor Vella, Anthony T. Remove constraint Advisor: Vella, Anthony T. Language English [eng] Remove constraint Language: English [eng]

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  • The role of costimulation and adjuvants in the development of T cell effector and memory responses

    Creator:
    Maxwell, Joseph R.
    Abstract:
    T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
    Resource Type:
    Dissertation
    Full Text:
    Kerkvliet provided funding and facilities for the work performed by Carl Ruby. Anthony T. Vella was the

  • Uncovering the mechanism of IL-4-mediated T cell survival

    Creator:
    Moscibrocki, Cathleen M.
    Abstract:
    Although IL-4 is a well-characterized multi-functional cytokine, its role as a survival factor in T cells is not completely understood. In an attempt to uncover IL-4-mediated survival, we studied caspase activation in primary mouse T lymphocytes undergoing death by neglect, activation-induced or steroid-induced cell death. Here, we identify the executioner...
    Resource Type:
    Masters Thesis
    Full Text:
    of IL-4-mediated T Cell Survival. Abstract approved: Anthony T. Vella Although IL-4 is a well

  • Characterization of CTIP1 interaction with HP1

    Creator:
    Huddleston, Cortny
    Abstract:
    COUP-TF interacting protein 1 (CTIP1) is a novel C2H2 zinc finger protein that mediates transcriptional repression of ARP1, a member of the COUP-TF subfamily of orphan nuclear receptors [1]. Here we show that CTIP1 interacts with heterochromatin-associated protein 1 (HP1) in vitro and in cells. This interaction suggests the existence...
    Resource Type:
    Undergraduate Thesis

  • Integrating Environment, Safety and Health Management Systems in Support of Lean Outcomes

    Creator:
    Kruse, Travis M.
    Abstract:
    Life cycle exposures to hazards from existing and newly developed products and production processes, demands from external stakeholders for compliance with regulations, requirements from internal stakeholders for connecting management systems to lean company initiatives and market pressures have motivated U.S. based semiconductor companies to adopt an integrated-lean approach to environment,...
    Resource Type:
    Dissertation
    Full Text:
    Anthony T. Veltri Life cycle exposures to hazards from existing and newly developed products and

  • West Nile virus : forecasting models for a resurging vector-borne disease in Arizona, U.S.A.

    Creator:
    Roldan, Josiah Javier
    Abstract:
    West Nile Virus (WNV), a vector-borne disease continues to be a serious threat to public health in the United States, particularly in the Southwest region. While all the states in the U.S. experienced a decreasing trend of WNV disease in 2010, the state of Arizona experienced a sharp increase from...
    Resource Type:
    Dissertation
    Full Text:
    : Anthony T. Veltri West Nile Virus (WNV), a vector-borne disease continues to be a serious threat to

  • Design for safety : a case study at a university examining congruency and integration

    Creator:
    Sumner, Rita Finn.
    Abstract:
    The purpose of this study was to develop a conceptual framework to enhance the redesign of a safety system. To identify the limitations of the current safety system, the concepts of congruency and integration of the safety function within a specific university environment were examined through a case study methodology....
    Resource Type:
    Masters Thesis
    Full Text:
    Case Study at a University Examining Congruency and Integration. Abstract approved: Anthony T

  • A framework for assessing the environmental, safety, and health strategy in an organization

    Creator:
    O'Malley, Brian C.
    Abstract:
    Over the past decade, the business sector has come under increasing pressure to improve their environmental, safety, and health (ESH) performance. This pressure has stemmed from both external and internal sources with the organization. Public image, legislative and regulatory requirements, stakeholder awareness of environmental performance, sustainable development, and changing corporate...
    Resource Type:
    Masters Thesis
    Full Text:
    approved: Anthony T. Veltri Over the past decade, the business sector has come under increasing pressure

  • An analysis of Benton County small businesses' emergency and disaster preparedness

    Creator:
    Chona, Tiffany L.
    Abstract:
    Natural Hazards are a potential risk to Benton County small businesses. However, little has been done to help prepare, respond, recover or resume business following a significant disastrous event. 93 small businesses in Benton County responded to a mailed survey, and 10 additional small businesses participated in both mailed surveys...
    Resource Type:
    Masters Thesis
    Full Text:
    . Abstract approved: Anthony T. Veltri Natural Hazards are a potential risk to Benton County small

  • Establishing the link between construction fatalities and disabling injuries and the design for construction safety concept

    Creator:
    Behm, Michael
    Abstract:
    Construction remains the most hazardous industry in the United States in terms of the aggregate number of fatalities. Twenty percent of all occupational related fatalities occur in construction; approximately three construction workers die per calendar day. Moreover, this trend has been prevalent for too long. One method to reduce this...
    Resource Type:
    Dissertation
    Full Text:
    Abstract approved: Anthony T. Veltri Construction remains the most hazardous industry in the United

  • Refining a more complete theory of environment, safety, and health management strategy using case studies

    Creator:
    Maxwell, Elisabeth D.
    Abstract:
    Environment, safety and health (ESH) research has a strong tradition of conducting research in manufacturing to improve workplace ESH conditions and has tied its management strategy and technical practices to many significant priorities: illness and injury prevention, environmental sustainability, corporate social responsibility, compliance with regulatory and insurance requirements, and dealing...
    Resource Type:
    Dissertation
    Full Text:
    :____________________________________________ Anthony T. Veltri Environment, safety and health (ESH) research has a strong tradition