Index Catalog // ScholarsArchive@OSU

Initial in vitro and in vivo Characterization of the Membrane Trafficking Protein Fer1L6

Creator:: Wolk, Chelsea
Abstract:: A fundamental difference between prokaryotic and eukaryotic cells is the presence of membrane bound organelles in eukaryotes. The dynamics of membrane trafficking within the cell are responsible for everything from intercellular communication and cell homeostasis, to mitosis, cell migration, and differentiation. These processes require exocytosis and compensatory endocytosis, often working...
Resource Type:: Dissertation
Full Text:: quiescent until triggered by a messenger, such as calcium. Exocytosis is primarily carried out by SNARE

Evaluation of zebrafish (Brachydanio rerio) as a model for carcinogenesis

Creator:: Tsai, Hsi-Wen
Abstract:: Zebrafish (Brachydanio rerio) are small, freshwater teleost fishes in the family Cyprinidae, the true minnows. They are native to the tropical latitudes of India, but have become widespread through their use as aquarium fish and as models for several branches of biological research. Their ease of rearing, short generation time,...
Resource Type:: Dissertation
Full Text:: that cause cancer. Species that may be useful as both laboratory models and field monitors are of

Developing rapid in vivo assays to investigate structure response relationships

Creator:: Truong, Lisa
Abstract:: Incorporation of nanoparticles (NPs) into consumer products is on the rise and human exposure to NPs is unavoidable. Currently, there is insufficient data to assess the safety of nanoparticles. I conducted a series of five studies using the zebrafish model to determine which NP components (i.e., core material or surface...
Resource Type:: Dissertation
Full Text:: encouraging and providing me lots of opportunities such as going to China, attending numerous conferences

Utilization of the Zebrafish Model for Investigating Nitrated Polycyclic Aromatic Hydrocarbon Developmental Toxicity

Creator:: Chlebowski, Anna C.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are among the most widely known and studied environmental contaminants, originating from a range of natural and anthropogenic sources. PAHs are known to occur in the environment as complex mixtures, containing both unsubstituted PAHs, as well as a range of PAH derivatives. Among the less-studied of...
Resource Type:: Dissertation
Full Text:: Johnson who make the laboratory possible. Huge thanks as well to Dr. Lisa Truong, who does a million

Establishing Larval Zebrafish as an In Vivo Model Organism for Characterizing the Roles of Otoferlin, a Sensory Hair Cell Protein Essential for Hearing

Creator:: Chatterjee, Paroma
Abstract:: Auditory defects and disorders are prevalent at all ages and affect 8% of the population in developed nations including newborns and children. Congenital hearing loss is the most common birth defect and it is estimated that 1 in 1000 children are affected by deafness at birth or before the onset...
Resource Type:: Dissertation
Full Text:: , 2016. Title: Establishing Larval Zebrafish as an In Vivo Model Organism for Characterizing the

Developmental neurobehavioral toxicity of bisphenol A in zebrafish (Danio rerio)

Creator:: Saili, Katerine Schletz
Abstract:: Billions of pounds of bisphenol A (BPA) are produced annually around the globe for the manufacture of numerous consumer products, including polycarbonate food and water containers, the protective resin linings of food cans, thermal printing paper, and dental fillings. BPA exposure during nervous system development has been associated with learning...
Resource Type:: Dissertation
Full Text:: Zebrafish (Danio rerio) AN ABSTRACT OF THE DISSERTATION OF Katerine

‘Tis a Gift to be Simple : On Passive Sampling and Compatible Techniques for Reducing the Complexity of Environmental Mixtures

Creator:: Bergmann, Alan J.
Abstract:: Assessing the risk from exposure to a chemical mixture in the environment can seem prohibitively challenging. Most components of the mixture are not readily identifiable, chemicals may interact to cause other-than-additive toxicity, and the number of potential combinations of environmental contaminants is enormous. These challenges can make it seem impossible...
Resource Type:: Dissertation
Full Text:: , eliminated priority pollutants as suspect toxicants and identified responsible toxicants. Specifically

In vivo assessment of nanomaterial-induced toxicity using embryonic zebrafish

Creator:: Usenko, Crystal Y.
Abstract:: Due to their unique physical, chemical, and magnetic properties, nanomaterials have great potential for industrial development. There is a pressing need to develop rapid whole animal-based testing assays to assess the potential toxicity of engineered nanomaterials. To meet this challenge the embryonic zebrafish model was employed to determine the toxicity...
Resource Type:: Masters Thesis
Full Text:: industrial development. There is a pressing need to develop rapid whole animal-based testing assays to

Pseudoloma neurophilia in the Zebrafish (Danio rerio) : Consequences of Infection on Neurobehavioral and Biomedical Research using a Burgeoning Model Organism

Creator:: Spagnoli, Sean
Abstract:: Since its inception as a laboratory animal in the early 1970s, the zebrafish has proven itself a rising star in the world of comparative biomedical sciences due to its short generation time, ease of care, external fertilization, and transparent larvae. In a very few decades, the zebrafish has been utilized...
Resource Type:: Dissertation
Full Text:: . Kent Since its inception as a laboratory animal in the early 1970s, the zebrafish has proven

Automated manipulation of zebrafish embryos for high-throughput toxicology screening of nanomaterials

Creator:: Mandrell, David
Abstract:: The field of nanotechnology has been rapidly developing new materials. These materials have become incorporated into consumer products and the environment after only minimal assessment of their effects on human health or the environment. The toxicity of these new nanomaterials remains unknown due to the unpredictable nature of the core...
Resource Type:: Masters Thesis
Full Text:: as whether to use cell culture or the whole animal to test nanotoxicity. Cell culture offers the

ScholarsArchive@OSU

Initial in vitro and in vivo Characterization of the Membrane Trafficking Protein Fer1L6

Evaluation of zebrafish (Brachydanio rerio) as a model for carcinogenesis

Developing rapid in vivo assays to investigate structure response relationships

Utilization of the Zebrafish Model for Investigating Nitrated Polycyclic Aromatic Hydrocarbon Developmental Toxicity

Establishing Larval Zebrafish as an In Vivo Model Organism for Characterizing the Roles of Otoferlin, a Sensory Hair Cell Protein Essential for Hearing

Developmental neurobehavioral toxicity of bisphenol A in zebrafish (Danio rerio)

‘Tis a Gift to be Simple : On Passive Sampling and Compatible Techniques for Reducing the Complexity of Environmental Mixtures

In vivo assessment of nanomaterial-induced toxicity using embryonic zebrafish

Pseudoloma neurophilia in the Zebrafish (Danio rerio) : Consequences of Infection on Neurobehavioral and Biomedical Research using a Burgeoning Model Organism

Automated manipulation of zebrafish embryos for high-throughput toxicology screening of nanomaterials

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