During the depression era, millions of Americans listened to the weekly radio
addresses given by Father Charles Edward Coughlin. He devoted his career to
speaking out against the evils of America and felt it his duty to warn Americans
against the perpetrators of this evil. But after 1934, the tone...
Utilizing nanocarrier based drug delivery for improving the magnitude of efficacy of chemotherapeutic agents in many diseases has acquired more attention in research applications. It has shown promising results in both preclinical and clinical trials. The Food and Drug Administration (FDA) has approved many of these polymeric carriers, and tens...
Explosively erupting volcanoes and megathrust earthquakes (Mw 8+ magnitude) occur at subduction zones and adjacent volcanic arcs. Volcanic eruptions are observed occurring close in time to megathrust earthquakes in the historical record from at least the 18th century CE to present in locations globally, including Japan in 1707 CE (Chesley...
TAC is the most commonly used medication in post transplantation maintenance immunosuppression therapy. TAC lipophilicity and its erratic oral absorption especially in the presence of food intake result in great intra- and interpatient pharmacokinetic variations. Complicated dosing and frequent required therapeutic monitoring is thought to be the main cause of...
The ~5 km3, 4.54 to 4.09 Ma Caspana Ignimbrite of the Altiplano-Puna Volcanic Complex (APVC) of the Central Andes records the eruption of an andesite and two distinct rhyolitic magmas. It provides a unique opportunity to investigate the production of silicic magmas in a continental arc flare-up, where small volumes...
Agricultural water supplies are becoming increasingly uncertain in the western United States due to rising demand from competing water users, environmental restrictions on surface water withdrawals due to water quality and endangered species concerns, and, potentially, climate-induced hydrological changes. Since many rural areas in the West depend economically upon irrigated...
Poor aqueous solubility of a large number of newly discovered chemical entities is posing a significant challenge for the formulation industry and is delaying their drug development. The number of formulation techniques available to solubilize these poorly soluble molecules is very limited. In addition to that, traditional formulation methods involve...
Studies of Hawaiian volcanoes contribute valuable insights about Earth processes and mantle evolution, and are fundamental for understanding the construction of the largest volcanoes on terrestrial planets. The pre-shield stage exists in every Hawaiian volcano, but is usually blanketed by high volume tholeiitic lava flows during the main shield stage....
The federal government owns 60 percent of Oregon’s forests and, since 1908, has shared proceeds from federal forest timber harvests with counties. These revenues
have provided a relatively stable source of funds for the provision of services by county governments in Oregon. Shared revenues from US Forest Service (USFS)
lands...
Dental disease is a very prevalent and costly disease in which the symptoms, not the disease, are currently being treated. The disease is caused by pathogenic oral bacteria, many of which are a part of the Mutans Streptococci. The objective of this thesis was to find a natural substance that...