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Bacillus subtilis endospore coat protein solubilization methods for studying effects of high pressure precessing

Creator:: Gandhi, Kalpesh K.
Abstract:: Spores of foodborne pathogens such as Clostridium botulinum, Clostridium perfringens and Bacillus cereus are widely distributed in nature. Presence of those spores in food products, particularly C. botulinum spores in vacuum packed, ready-to-eat low-acid products, is a great safety concern. The research here described is a first effort towards understanding...
Resource Type:: Masters Thesis
Full Text:: . PROTEIN SOLUBILIZATION METHODS FOR STUDYING BACTERIAL ENDOSPORE COAT PROTEINS Gandhi KK*, Anderson SR1

Aging and oxidative damage to mitochondrial membrane proteins

Creator:: Tong, Tony T.
Abstract:: Mitochondria provide energy for biological cells to function, but this process is also a source of oxygen radicals that are capable of damaging nearby proteins. Mitochondrial protein damage can eventually lead to cell death, especially in the case of heart cells, where mitochondria are present in the highest concentrations. As...
Resource Type:: Honors College Thesis
Full Text:: . Mitochondrial protein damage can eventually lead to cell death, especially in the case of heart cells, where

Functional, structural and evolutionary analyses of the ferritin-like superfamily of proteins

Creator:: Cooley, Richard Bleier
Abstract:: The ferritin-like superfamily (FLSF) of proteins is composed of a wide variety of functionally diverse proteins involved in oxygen dependent metal-mediated electron transfer reactions. Their biological importance is exemplified by the fact FLSF proteins are found in almost every organism from all three domains of life. Their functions range from...
Resource Type:: Dissertation
Full Text:: particular groups of FLSF proteins: bacterial multicomponent monooxygenases (BMMs) and rubrerythrins. BMMs

Genomic identification of candidate inclusion membrane proteins in Chlamydial species and microscopic analysis

Creator:: Blake, Nathanael A.
Abstract:: The Chlamydiaceae are a family of obligate intracellular bacteria with a unique biphasic developmental cycle. The replicating, metabolically active, intracellular phase bacteria (RBs) grow within a cellular vacuole know as the inclusion. Since the proteins the Chlamydiaceae secrete into this membrane are the means of host/parasite interaction, they have long...
Resource Type:: Honors College Thesis
Full Text:: proteins, protein localization Corresponding e-mail: aure.entuluva@gmail.com

Characterization of germinant receptors in Clostridium perfringens non-food-borne isolates

Creator:: Banawas, Saeed S.
Abstract:: C. perfringens is a Gram-positive, spore-forming, anaerobic pathogenic bacterium capable of causing a wide variety of diseases in both humans and animals. However, the two most common illnesses in humans are C. perfringens type A food poisoning (FP) and non-food-borne (NFB) gastrointestinal (GI) illnesses . These two major diseases are...
Resource Type:: Masters Thesis
Full Text:: , that GerAA is a major germinant receptor protein in NFB spores. © Copyright by Saeed

Physicochemical Properties of Frozen Fish Muscle as Affected by Trimethylamine-N-oxide demethylase (TMAOase)

Creator:: Lee, Jinhwan
Abstract:: Gadoid fish, like Alaska pollock and Pacific whiting, have a high level of trimethylamine-N-oxide demethylase (TMAOase) that catalyzes the breakdown of trimethylamine-N-oxide (TMAO) to formaldehyde (FA) and dimethylamine (DMA) even during frozen storage. FA reacts with amino acid residues to promote covalent cross-links in the formation of inter- and intramolecular...
Resource Type:: Dissertation
Full Text:: - and FA-induced protein denaturation followed by aggregation. The primary goal of the study

Characterization and Validation of Neisseria gonorrhoeae Proteins GmhAGC and NGO1985 as Molecular Targets for Development of Novel Anti-gonorrhea Therapeutic Interventions

Creator:: Wierzbicki, Igor H.
Abstract:: The sexually transmitted disease gonorrhea, caused by the Gram-negative bacterium and obligate human pathogen Neisseria gonorrhoeae, remains a significant health and economic burden worldwide. In the absence of a protective vaccine, antimicrobial agents are the only pharmacological intervention for patients with gonorrhea. However, due to the remarkable ability of gonococcus...
Resource Type:: Dissertation
Full Text:: . gonorrhoeae GmhAGC is essential for lipooligosaccharide (LOS) synthesis and pivotal for bacterial viability

Hard spheres within classical density functional theory and Min proteins in Escherichia coli

Creator:: Schulte, Jeff B.
Abstract:: This thesis reports on computational research in two different areas. I first discuss the Min-protein system found within Escherichia coli. Following this I discuss an extended investigation into improving free energy functionals that are used within Classical Density Functional Theory in order to model water. Chapter 2 examines the dynamics...
Resource Type:: Dissertation
Full Text:: -protein system found within Escherichia coli. Following this I discuss an extended investigation into

Surface-exposed proteins in the pathogenesis of Mycobacterium avium subsp. hominissuis

Creator:: McNamara, Michael J.
Abstract:: Mycobacterium avium subsp. hominissuis (MAH) is a pervasive environmental bacterium that can cause opportunistic infections in humans. Among the most robust and hardy members of the Mycobacterium genus, M. avium can persist and thrive in a range of challenging environments, including many which place it in direct contact with humans....
Resource Type:: Dissertation
Full Text:: Family Protein, MAV_2921, and Localizes to the Bacterial Surface

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

Creator:: Alzhanov, Damir T.
Abstract:: The majority of our modern understanding of bacterial pathogenesis is based on the strategy that involves screening bacterial genomes for the presence of the genes encoding pathogenic factors, and analysis of these genes via forward and reverse genetics. Chlamydiae represent a unique group of pathogenic bacteria in which it is...
Resource Type:: Dissertation
Full Text:: bacterial OmpA protein, exposed on the surface of EB (143), and heparan sulfate containing

ScholarsArchive@OSU

Bacillus subtilis endospore coat protein solubilization methods for studying effects of high pressure precessing

Aging and oxidative damage to mitochondrial membrane proteins

Functional, structural and evolutionary analyses of the ferritin-like superfamily of proteins

Genomic identification of candidate inclusion membrane proteins in Chlamydial species and microscopic analysis

Characterization of germinant receptors in Clostridium perfringens non-food-borne isolates

Physicochemical Properties of Frozen Fish Muscle as Affected by Trimethylamine-N-oxide demethylase (TMAOase)

Characterization and Validation of Neisseria gonorrhoeae Proteins GmhAGC and NGO1985 as Molecular Targets for Development of Novel Anti-gonorrhea Therapeutic Interventions

Hard spheres within classical density functional theory and Min proteins in Escherichia coli

Surface-exposed proteins in the pathogenesis of Mycobacterium avium subsp. hominissuis

The role of chlamydial inclusion membrane proteins in host-pathogen interaction and the development of novel methods for studying chlamydial biology

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