A vital aspect of concrete construction is quality assurance and control (QA/QC). Engineered structures must meet pre-determined and agreed-upon strength and durability requirements. Concrete falls into a specific category of infrastructure material because in most cases, these strength and durability requirements cannot be found until the material has at least...
Human cathelicidin antimicrobial peptide (CAMP/LL-37) is a cationic antimicrobial peptide that is widely expressed by myeloid and epithelial cells at the human-environment interface. It possesses broad spectrum antimicrobial capacity against bacteria, fungi and viruses. In addition to its direct antimicrobial activity, CAMP/LL-37 also attracts and recruits monocytes, neutrophils and other...
The primary goal of my studies was to elucidate the mechanisms for the well-recognized interaction between two nutrients, vitamins E and K. The outcomes from my studies assess mechanisms for adverse effects of vitamin E and provide novel information on mechanisms for vitamin K homeostasis. These findings will provide information...
My thesis is comprised of two articles, titled "Journeying Through (An)Other World: Examining the Role of Magic and Transformational Otherness in Sir Gawain and the Green Knight" and "Magic, Muggles, and Mudbloods: Examining Magical Otherness in J.K. Rowling's Harry Potter Series." The introduction frames the thematic, theoretical, and critical connections...
In this thesis I explore the ways in which twenty-first century Americans have access
to Geoffrey Chaucer and his works. I look at issues surrounding Chaucer within the
canon debate, high school history and literature textbooks, and Chaucer in popular
culture, such as in movies like A Knight's Tale. I...
Recent state and national standards have increased the interest in engineering at the K-12 level. Science standards, in particular, have begun to make the case for including engineering throughout the K-12 scope of study. Despite the increased attention to engineering, the characteristics and uniqueness of the field of engineering are...
This thesis presents two related studies on the methodology for creating, and
subsequently analyzing, an inverse food web model of an intertidal seagrass bed. The first study (Chapter 2) describes, for the first time in the literature, a method for incorporating isotopic information gained from Bayesian mixing models into an...
The human cathelicidin antimicrobial peptide (CAMP) is a broad spectrum microbicidal agent and modulator of both the innate and adaptive immune system. It is induced by 1,25-dihydroxyvitamin D (1,25(OH)₂D₃) through activation of the vitamin D receptor (VDR) and primary bile salts through activation of the xenobiotic nuclear receptor farnesoid X...
The electric power grids of countries across the globe rely on load and generation forecasting to know when, where, and how much resources need to be dispatched to sustain proper grid operation. Because of this, forecasting needs to be highly accurate to avoid unnecessary resource dispatch which can be costly....
Molecular chirality plays a critical role in chemistry, biology, and medicine. To study and better understand conformational chirality, it is necessary to obtain structurally interesting molecules that exhibit this form of chirality. Our lab utilizes total synthesis and methodological development to obtain conformationally chiral natural products of interest. We believe...