Index Catalog // ScholarsArchive@OSU

Creator:: Parachini-Winter, Cyril
Abstract:: Lymphoma (LSA) is one of the most common canine malignancies, and is almost invariably a terminal disease. Epigenetic changes in canine and human lymphomas have been linked to disease progression and poor prognosis, leading to the development of epigenetic-targeted therapies which have shown promise in treating various forms of human...
Resource Type:: Masters Thesis
Full Text:: : ______________________________________________________ Shay Bracha Lymphoma (LSA) is one of the most common canine

Creator:: Weinman, Marcus
Abstract:: Many humans and canines alike suffer from osteosarcoma, which is often metastatic, resistant to chemotherapy, and frequently fatal. The mechanisms through which osteosarcoma cells acquire resistance to chemotherapy are not entirely understood, and the role of exosomes as intercellular mediators of this resistance in osteosarcoma is unknown. Using established canine...
Resource Type:: Masters Thesis
Full Text:: Osteosarcoma. Abstract approved: ______________________________________________________ Shay

Creator:: Weinman, Marcus Andrew
Abstract:: Canine transitional cell carcinoma (TCC) has been shown to have a substantial inflammatory component. It exhibits genotypic and morphologic elements that resemble its human counterpart. Cyclooxygenases (COX) are key enzymes in the synthesis of proinflammatory molecules, such as prostaglandins. Excess prostaglandin production through cyclooxygenases may promote oncogenesis and progression of...
Resource Type:: Honors College Thesis
Full Text:: . Weinman, Author Acknowledgements I would like to thank Dr. Shay Bracha for his mentorship

Creator:: Viall, Austin K.
Abstract:: The serotonergic system plays a significant regulatory role in osteoblast differentiation and proliferation. Serotonin (five-hydroxytryptamine or 5HT) may promote or inhibit osteoblast proliferation depending upon the serotonin receptor isoforms expressed by the cell. Classically, 5HT receptor 1B (5HTR1B) reduces osteoblast proliferation by inhibiting phosphorylation of the cAMP response element binding...
Resource Type:: Masters Thesis
Full Text:: Shay Bracha Abstract: The serotonergic system plays a significant regulatory role in osteoblast

ScholarsArchive@OSU