Sulforaphane is an isothiocyanate derived from cruciferous vegetables and has been under investigation as a cancer chemopreventive agent for over two decades. The compound is well tolerated and has been shown to slow cancer progression in several different pre-clinical models of carcinogenesis, such as of the lung, breast and colon....
The causes of the global biodiversity crisis are varied and complex. Anthropogenic threats may act in isolation, or interact additively or synergistically with each other or with natural stressors to affect sensitive taxa. The recent emergence of many infectious diseases in wildlife has brought attention to the role of disease...
Animals can be naturally exposed simultaneously to multiple stressors. These include habitat changes, contaminants, diseases, invasive species, parasitism, and predation. Exposure to various combinations of biotic and abiotic stressors may induce behavioral changes that affect the way an individual interacts within its environment.Like other groups of organisms, amphibians are exposed...
Olympia oysters, “Ostrea conchaphila,” were once common along the west coast of North America. A popular delicacy, native oyster populations began to decline in the late 1800’s due to over‐harvest, degraded water quality, and habitat loss. Interest in re‐establishing the native oyster in a small Oregon estuary, Netarts Bay, culminated...
Increasingly popular methods for managing impacts of tourism in nature-based settings include collaborative and voluntary codes of conduct. In southeast Alaska, for example, the Tourism Best Management Practices (TBMP) in Juneau and Wilderness Best Management Practices (WBMP) in Tracy Arm-Fords Terror Wilderness have been created to address shore and marine...
Microfinance, or the technique of lending small amounts of money to the world's poor for productive activities, has emerged as a dominant approach to poverty alleviation among international development organizations. However, consensus does not yet exist as to the best mechanism for delivery of loans. While most organizations simply offer...
Oceanic fronts mark the boundary between two water masses and are often sites of complex bio-physical processes and multi-trophic level interactions, making them particularly important features in marine ecosystems. As global climate change induces multi-scale shifts in the driving physical mechanisms of fronts, spatiotemporal tracking of frontal variability can aid...
An increase in frequency and severity of hot, dry summers has been associated with a dramatic shift in the coniferous forests of western Oregon’s valleys, especially on the privately-owned properties along the low-elevation edges of these valleys. Various conifer species, including Douglas-fir (Pseudotsuga menziesii), are declining in these forests, leaving...
On January 8th, 2011 tragedy struck in Tucson, Arizona. A gunman opened fire on Representative Gabrielle Giffords' "Congress on Your Corner" event, wounding thirteen and killing six ("Arizona Shooting"). Four days later, President Obama spoke to a grieving crowd at the University of Arizona's McKale Memorial Center. This study seeks...
Despite the advances in surgery, physical therapy, and pharmaceutical agents, muscle
dysfunction (i.e., atrophy and weakness) continues to impair recovery from an anterior
cruciate ligament (ACL) injury and surgery. Ischemia-reperfusion injury during surgery
and the subsequent limb disuse are two events experienced by patients having ACL
surgery. Oxidative stress and...