Circadian clocks coordinate molecular, cellular, physiological, and behavioral processes with the 24-hour solar day. While clock functions are well understood in young animals, it is not clear how aging or neurodegenerative disease affects the various levels of the circadian system. A common symptom of many neurodegenerative diseases including Alzheimer’s disease...
In this piece of original work, I employ a Kunderian approach to fiction. The purpose of my novel is to examine how the causative element, a pivotal moment of change for a cast of characters, changes spatially and temporally. In Posthumously Yours, I explore themes of trauma, loss, and grief...
Most benthic marine fishes have a biphasic life cycle with a dispersive pelagic larval stage that spends weeks to months in the plankton before metamorphosing into juveniles and settling to benthic habitats. The magnitude of mortality during the early life stages of marine fishes typically drives variability in year-class strength....
The bioavailability of chemical compounds in the marine environment fundamentally influences the growth and physiology of microorganisms. Organic and inorganic chemicals that are produced by some marine plankton can be consumed by other plankton for energy production, growth, or to initiate essential physiological processes. Cultures of the diatom Thalassiosira pseudonana,...
Ferlins are a family of calcium-sensitive proteins involved in fusion and fission membrane trafficking events. There are six ferlin members: dysferlin, otoferlin, myoferlin, Fer1L4, Fer1L5, and Fer1L6. Previous research shows the first three ferlins play a pathophysiological role in humans, while the other three remain uncharacterized. Fer1L6 is one of...
Aging is a complex biological phenomenon that alters many different physiological processes. Although many age-related phenotypes, such as neurodegeneration, weakening circadian rhythms, and inflammaging, are well-studied, the links between them are not. To elucidate these links we created an inflammation-like state in Drosophila melanogaster by overexpressing Relish (Rel), an NFκB...
Various natural language processing (NLP) tasks necessitate deep models that are fast, efficient, and small based on their ultimate application at the edge or elsewhere. While significant investigation has furthered the efficiency and reduced the size of these models, reducing their downstream latency without significant trade-offs remains a difficult task....
Observed declines in native pollinator species worldwide has generated concern and focused research into the disturbances, past and present, which may have contributed to these losses. In grasslands, for example, habitat degradation and fragmentation from historical and current crop production and livestock grazing has left only a few remnants of...
Cabbage maggot, Delia radicum (Diptera: Anthomyiidae) impacts the production of Brassicaceae crops worldwide. The larva feed on the roots of crops causing reductions in yields due to impaired root function and unmarketability of crops. Chemical and cultural management programs are commonly used to control cabbage maggot with varying rates of...
Fluid simulation is an interesting research problem with a wide range of applications including mechanical engineering, special effects in movies and games, and scientific simulation. Due to the complex nature of typical fluid flow equations, there are circumstances where a full volumetric fluid simulation may not be necessary to generate...