Index Catalog // ScholarsArchive@OSU

Accelerated Identification of Proteins by Mass Spectrometry by Employing Covalent Pre-Gel Staining with Uniblue A

Creator:: Mata-Gomez, Marco A., Yasui, Matthew T., Guerrero-Rangel, Armando, Valdes-Rodrıguez, Silvia, and Winkler, Robert
Abstract:: Background: The identification of proteins by mass spectrometry is a standard method in biopharmaceutical quality control and biochemical research. Prior to identification by mass spectrometry, proteins are usually pre-separated by electrophoresis. However, current protein staining and de-staining protocols are tedious and time consuming, and therefore prolong the sample preparation time...
Resource Type:: Article
Full Text:: School of Chemical, Biological and Environmental Engineering, Oregon State University, Corvallis, Oregon

The Aryl Hydrocarbon Receptor Mediates Leflunomide- Induced Growth Inhibition of Melanoma Cells

Creator:: O’Donnell, Edmond F., Kopparapu, Prasad Rao, Koch, Daniel C., Jang, Hyo Sang, Phillips, Jessica Lynne, Tanguay, Robert L., Kerkvliet, Nancy I., and Kolluri, Siva Kumar
Abstract:: A novel role of the dihydroorotatedehydrogenase (DHODH) inhibitor leflunomide as a potential anti-melanoma therapy was recently reported (Nature 471: 518-22, 2011). We previously reported that leflunomide strongly activates the transcriptional activity of the Aryl Hydrocarbon Receptor (AhR). We therefore tested whether the AhR regulates the anti-proliferative effects of leflunomide in...
Resource Type:: Article
Full Text:: , Oregon, United States of America, 2Department of Environmental and Molecular Toxicology, Oregon State

The α-Tocopherol Transfer Protein Is Essential for Vertebrate Embryogenesis

Creator:: Miller, Galen W., Ulatowski, Lynn, Labut, Edwin M., Lebold, Katie M., Manor, Danny, Atkinson, Jeffrey, Barton, Carrie L., Tanguay, Robert L., and Traber, Maret G.
Abstract:: The hepatic α-tocopherol transfer protein (TTP) is required for optimal α-tocopherol bioavailability in humans; mutations in the human TTPA gene result in the heritable disorder ataxia with vitamin E deficiency (AVED, OMIM #277460). TTP is also expressed in mammalian uterine and placental cells and in the human embryonic yolk-sac, underscoring...
Resource Type:: Article
Full Text:: , United States of America, 4 Department of Environmental and Molecular Toxicology, Oregon State

Differential surface activation of the A1 domain of von Willebrand factor

Creator:: Tronic, Elaine H., Yakovenko, Olga, Weidner, Tobias, Baio, Joe E., Penkala, Rebecca, Castner, David G., and Thomas, Wendy E.
Abstract:: The clotting protein von Willebrand factor (VWF) binds to platelet receptor glycoprotein Ibα (GPIbα) when VWF is activated by chemicals, high shear stress, or immobilization onto surfaces. Activation of VWF by surface immobilization is an important problem in the failure of cardiovascular implants, but is poorly understood. Here, the authors...
Resource Type:: Article
Full Text:: : School of Chemical, Biological and Environmental Engineering, Oregon State University, Corvallis, Oregon

Uncertainty analysis: an evaluation metric for synthesis science

Creator:: Harmon, Mark E., Fasth, Becky, Halpern, Charles B., and Lutz, James A.
Abstract:: The methods for conducting reductionist ecological science are well known and widely used. In contrast, those used in the synthesis of ecological science (i.e., synthesis science) are still being developed, vary widely, and often lack the rigor of reductionist approaches. This is unfortunate because the synthesis of ecological parts into...
Resource Type:: Article
Full Text:: science Uncertainty analysis: an evaluation metric for synthesis science Harmon, M. E., Fasth, B

Elemental Markers in Elasmobranchs: Effects of Environmental History and Growth on Vertebral Chemistry

Creator:: Smith, Wade D., Miller, Jessica A., and Heppell, Selina S.
Abstract:: Differences in the chemical composition of calcified skeletal structures (e.g. shells, otoliths) have proven useful for reconstructing the environmental history of many marine species. However, the extent to which ambient environmental conditions can be inferred from the elemental signatures within the vertebrae of elasmobranchs (sharks, skates, rays) has not been...
Resource Type:: Article
Full Text:: Elemental Markers in Elasmobranchs: Effects of Environmental

Factors Controlling Soil Microbial Biomass and Bacterial Diversity and Community Composition in a Cold Desert Ecosystem: Role of Geographic Scale

Creator:: Van Horn, David J., Van Horn, M. Lee, Barrett, John E., Gooseff, Michael N., Altrichter, Adam E., Geyer, Kevin M., Zeglin, Lydia H., and Takacs-Vesbach, Cristina D.
Abstract:: Understanding controls over the distribution of soil bacteria is a fundamental Understanding controls over the distribution of soil bacteria is a fundamental step toward describing soil ecosystems, understanding their functional capabilities, and predicting their responses to environmental change. This study investigated the controls on the biomass, species richness, and community...
Resource Type:: Article
Full Text:: & Environmental Engineering, Pennsylvania State University, University Park, Pennsylvania, United States of

Viewing forests through the lens of complex systems science

Creator:: Filotas, Elise, Parrott, Lael, Burton, Philip J., Chazdon, Robin L., Coates, K. David, Coll, Lluis, Haeussler, Sybille, Martin, Kathy, Nocentini, Susanna, Puettmann, Klaus J., Putz, Francis E., Simard, Suzanne W., and Messier, Christian
Abstract:: Complex systems science provides a transdisciplinary framework to study systems characterized by (1) heterogeneity, (2) hierarchy, (3) self‐organization, (4) openness, (5) adaptation, (6) memory, (7) non‐linearity, and (8) uncertainty. Complex systems thinking has inspired both theory and applied strategies for improving ecosystem resilience and adaptability, but applications in forest ecology...
Resource Type:: Article
Full Text:: Viewing forests through the lens of complex systems science

Near-Real-Time Acoustic Monitoring of Beaked Whales and Other Cetaceans Using a Seaglider (TM)

Creator:: Klinck, Holger, Mellinger, David K., Klinck, Karolin, Bogue, Neil M., Luby, James C., Jump, William A., Shilling, Geoffrey B., Litchendorf, Trina, Wood, Angela S., Schorr, Gregory S., and Baird, Robin W.
Abstract:: Correction 10 Aug 2012: Klinck H, Mellinger DK, Klinck K, Bogue NM, Luby JC, et al. (2012) Correction: Near-Real-Time Acoustic Monitoring of Beaked Whales and Other Cetaceans Using a Seaglider™. PLOS ONE 7(8): 10.1371/annotation/57ad0b82-87c4-472d-b90b-b9c6f84947f8.
Resource Type:: Article
Full Text:: mammal science. U.S. environmental laws, including the Endangered Species Act, the Marine Mammal

Density Can Be Misleading for Low-Density Species: Benefits of Passive Acoustic Monitoring

Creator:: Rogers, Tracey L., Ciaglia, Michaela B., Klinck, Holger, and Southwell, Colin
Abstract:: Climate-induced changes may be more substantial within the marine environment, where following ecological change is logistically difficult, and typically expensive. As marine animals tend to produce stereotyped, long-range signals, they are ideal for repeatable surveying. In this study we illustrate the potential for calling rates to be used as a...
Resource Type:: Article
Full Text:: University and Pacific Marine Environmental Laboratory, National Oceanic and Atmospheric Administration

ScholarsArchive@OSU

Accelerated Identification of Proteins by Mass Spectrometry by Employing Covalent Pre-Gel Staining with Uniblue A

The Aryl Hydrocarbon Receptor Mediates Leflunomide- Induced Growth Inhibition of Melanoma Cells

The α-Tocopherol Transfer Protein Is Essential for Vertebrate Embryogenesis

Differential surface activation of the A1 domain of von Willebrand factor

Uncertainty analysis: an evaluation metric for synthesis science

Elemental Markers in Elasmobranchs: Effects of Environmental History and Growth on Vertebral Chemistry

Factors Controlling Soil Microbial Biomass and Bacterial Diversity and Community Composition in a Cold Desert Ecosystem: Role of Geographic Scale

Viewing forests through the lens of complex systems science

Near-Real-Time Acoustic Monitoring of Beaked Whales and Other Cetaceans Using a Seaglider (TM)

Density Can Be Misleading for Low-Density Species: Benefits of Passive Acoustic Monitoring

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