Index Catalog // ScholarsArchive@OSU

Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice

Creator:: Zhang, Wei-Jian and Frei, Balz
Abstract:: In this study we investigated the role of astragaloside IV (AS-IV), one of the major active constituents purified from the Chinese medicinal herb Astragalus membranaceus, in LPS-induced acute inflammatory responses in mice in vivo and examined possible underlying mechanisms. Mice were assigned to four groups: vehicle-treated control animals; AS-IV-treated animals...
Resource Type:: Article
Full Text:: ] C. Chu, L.-W. Qi, E.-H. Liu, B. Li, W. Gao, and P. Li, “Radix astragali (Astragalus): latest

Assessing De Novo transcriptome assembly metrics for consistency and utility

Creator:: O’Neil, Shawn T. and Emrich, Scott J.
Abstract:: Background: Transcriptome sequencing and assembly represent a great resource for the study of non-model species, and many metrics have been used to evaluate and compare these assemblies. Unfortunately, it is still unclear which of these metrics accurately reflect assembly quality. Results: We simulated sequencing transcripts of Drosophila melanogaster. By assembling...
Resource Type:: Article

Lespedeza davurica (Lax.) Schindl. Extract Protects against Cytokine-Induced 𝛽-Cell Damage and Streptozotocin-Induced Diabetes

Creator:: Sharma, Bhesh Raj and Rhyu, Dong Young
Abstract:: This is the publisher’s final pdf. The published article is copyrighted by the author(s) and published by the Hindawi Publishing Corporation. The published article can be found at: http://dx.doi.org/10.1155/2015/169256
Resource Type:: Article
Full Text:: ,TheEndocrine System Pharmacology, Longman Group Ltd., London, UK, 2nd edition, 1991. [7] D. Cheng, B. Liang

Complete genome sequence of Nitrosomonas sp. Is79, an ammonia oxidizing bacterium adapted to low ammonium concentrations

Creator:: Bollmann, Annette, Sedlacek, Christopher J., Norton, Jeanette, Laanbroek, Hendrikus J., Suwa, Yuichi, Stein, Lisa Y., Klotz, Martin G., Arp, Daniel J., Sayavedra-Soto, Luis, Lu, Megan, Bruce, David, Detter, Chris, Tapia, Roxanne, Han, James, Woyke, Tanja, Pitluck, Sam, Pennacchio, Len, Nolan, Matt, Land, Miriam L., Huntemann, Marcel, Deshpande, Shweta, Han, Cliff, Chen, Amy, Kyrpides, Nikos, Movromatis, Konstantinos, Markowitz, Victor, Szeto, Ernest, Ivonova, Natalia, Mikhailova, Natalia, Pagani, Ioanna, Pati, Amrita, Peters, Lin, Ovchinnikova, Galina, Goodwin, Lynne A., and Lucas, Susan M.
Abstract:: Nitrosomonas sp. Is79 is a chemolithoautotrophic ammonia-oxidizing bacterium that belongs to the family Nitrosomonadaceae within the phylum Proteobacteria. Ammonia oxidation is the first step of nitrification, an important process in the global nitrogen cycle ultimately resulting in the production of nitrate. Nitrosomonas sp. Is79 is an ammonia oxidizer of high...
Resource Type:: Article
Full Text:: totaling 173.6 Mb of 454 data. All general aspects of li- brary construction and sequencing performed at

Evolutionary Biology for the 21st Century

Creator:: Losos, Jonathan B., Arnold, Stevan J., Bejerano, Gill, Brodie, E. D. III, Hibbett, David, Hoekstra, Hopi E., Mindell, David P., Monteiro, Antonia, Moritz, Craig, Orr, H. Allen, Petrov, Dmitri A., Renner, Susanne S., Ricklefs, Robert E., Soltis, Pamela S., and Turner, Thomas L.
Abstract:: We live in an exciting time for biology. Technological advances have made data collection easier and cheaper than we could ever have imagined just 10 years ago. We can now synthesize and analyze large data sets containing genomes, transcriptomes, proteomes, and multivariate phenotypes. At the same time, society's need for...
Resource Type:: Article
Full Text:: :// www.barcodeoflife.org/, Macaulay Li- brary—http://macaulaylibrary.org/). Pre- cise information on place, time, and

Population-Specific Regulation of Chmp2b by Lbx1 during Onset of Synaptogenesis in Lateral Association Interneurons

Creator:: Xu, Jun, Nonogaki, Mariko, Madhira, Ravi, Ma, Hsiao-Yen, Hermanson, Ola, Kioussi, Chrissa, and Gross, Michael K.
Abstract:: Chmp2b is closely related to Vps2, a key component of the yeast protein complex that creates the intralumenal vesicles of multivesicular bodies. Dominant negative mutations in Chmp2b cause autophagosome accumulation and neurodegenerative disease. Loss of Chmp2b causes failure of dendritic spine maturation in cultured neurons. The homeobox gene Lbx1 plays...
Resource Type:: Article

Differential surface activation of the A1 domain of von Willebrand factor

Creator:: Tronic, Elaine H., Yakovenko, Olga, Weidner, Tobias, Baio, Joe E., Penkala, Rebecca, Castner, David G., and Thomas, Wendy E.
Abstract:: The clotting protein von Willebrand factor (VWF) binds to platelet receptor glycoprotein Ibα (GPIbα) when VWF is activated by chemicals, high shear stress, or immobilization onto surfaces. Activation of VWF by surface immobilization is an important problem in the failure of cardiovascular implants, but is poorly understood. Here, the authors...
Resource Type:: Article
Full Text:: . Haemostasis 7, 24 (2009). 7S. Miura, C. Q. Li, Z. Cao, H. Wang, M. R. Wardell, and J. E. Sadler, J. Biol

Accelerated Identification of Proteins by Mass Spectrometry by Employing Covalent Pre-Gel Staining with Uniblue A

Creator:: Mata-Gomez, Marco A., Yasui, Matthew T., Guerrero-Rangel, Armando, Valdes-Rodrıguez, Silvia, and Winkler, Robert
Abstract:: Background: The identification of proteins by mass spectrometry is a standard method in biopharmaceutical quality control and biochemical research. Prior to identification by mass spectrometry, proteins are usually pre-separated by electrophoresis. However, current protein staining and de-staining protocols are tedious and time consuming, and therefore prolong the sample preparation time...
Resource Type:: Article

Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

Creator:: Rodriguez-Mari, Adriana, Wilson, Catherine, Titus, Tom A., Canestro, Cristian, BreMiller, Ruth A., Yan, Yi-Lin, Nanda, Indrajit, Johnston, Adam, Kanki, John P., Gray, Erin M., He, Xinjun, Spitsbergen, Jan, Schindler, Detlev, and Postlethwait, John H.
Abstract:: Mild mutations in BRCA2 (FANCD1) cause Fanconi anemia (FA) when homozygous, while severe mutations cause common cancers including breast, ovarian, and prostate cancers when heterozygous. Here we report a zebrafish brca2 insertional mutant that shares phenotypes with human patients and identifies a novel brca2 function in oogenesis. Experiments showed that...
Resource Type:: Article

Where to find 1.5 million yr old ice for the IPICS “Oldest-Ice” ice core

Creator:: Fischer, H., Severinghaus, J., Brook, Edward J., Wolff, E., Albert, M., Alemany, O., Arthern, R., Bentley, C., Blankenship, D., Chappellaz, J., Creyts, T., Dahl-Jensen, D., Dinn, M., Frezzotti, M., Fujita, S., Gallee, H., Hindmarsh, R., Hudspeth, D., Jugie, G., Kawamura, K., Lipenkov, V., Miller, H., Mulvaney, R., Parrenin, F., Pattyn, F., Ritz, C., Schwander, J., Steinhage, D., van Ommen, T., and Wilhelms, F.
Abstract:: The recovery of a 1.5 million yr long ice core from Antarctica represents a keystone of our understanding of Quaternary climate, the progression of glaciation over this time period and the role of greenhouse gas cycles in this progression. Here we tackle the question of where such ice may still...
Resource Type:: Article

ScholarsArchive@OSU

Astragaloside IV Inhibits NF-κB Activation and Inflammatory Gene Expression in LPS-Treated Mice

Assessing De Novo transcriptome assembly metrics for consistency and utility

Lespedeza davurica (Lax.) Schindl. Extract Protects against Cytokine-Induced 𝛽-Cell Damage and Streptozotocin-Induced Diabetes

Complete genome sequence of Nitrosomonas sp. Is79, an ammonia oxidizing bacterium adapted to low ammonium concentrations

Evolutionary Biology for the 21st Century

Population-Specific Regulation of Chmp2b by Lbx1 during Onset of Synaptogenesis in Lateral Association Interneurons

Differential surface activation of the A1 domain of von Willebrand factor

Accelerated Identification of Proteins by Mass Spectrometry by Employing Covalent Pre-Gel Staining with Uniblue A

Roles of brca2 (fancd1) in Oocyte Nuclear Architecture, Gametogenesis, Gonad Tumors, and Genome Stability in Zebrafish

Where to find 1.5 million yr old ice for the IPICS “Oldest-Ice” ice core

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