Index Catalog // ScholarsArchive@OSU

Formation of Complexes at Plasmodesmata for Potyvirus Intercellular Movement Is Mediated by the Viral Protein P3N-PIPO

Creator:: Wei, Taiyun, Zhang, Changwei, Hong, Jian, Xiong, Ruyi, Kasschau, Krisitin D., Zhou, Xueping, Carrington, James C., and Wang, Aiming
Abstract:: Intercellular transport of viruses through cytoplasmic connections, termed plasmodesmata (PD), is essential for systemic infection in plants by viruses. Previous genetic and ultrastructural data revealed that the potyvirus cyclindrical inclusion (CI) protein is directly involved in cell-to-cell movement, likely through the formation of conical structures anchored to and extended through...
Resource Type:: Article
Full Text:: College of Horticulture, Nanjing Agricultural University, Nanjing, People’s Republic of China, 4 Center of

Novel Pactamycin Analogs Induce p53 Dependent Cell-Cycle Arrest at S-Phase in Human Head and Neck Squamous Cell Carcinoma (HNSCC) Cells

Creator:: Guha, Gunjan, Lu, Wanli, Li, Shan, Liang, Xiaobo, Kulesz-Martin, Molly F., Mahmud, Taifo, Indra, Arup Kumar, and Ganguli-Indra, Gitali
Abstract:: Pactamycin, although putatively touted as a potent antitumor agent, has never been used as an anticancer drug due to its high cytotoxicity. In this study, we characterized the effects of two novel biosynthetically engineered analogs of pactamycin, de-6MSA-7-demethyl-7- deoxypactamycin (TM-025) and 7-demethyl-7-deoxypactamycin (TM-026), in head and neck squamous cell carcinoma...
Resource Type:: Article
Full Text:: treated with TM-025 and TM-026 for 72 h (Figs 5B and S4 Part A). Altogether, Fig 4. PCT analogs did not

Hyperdiverse Gene Cluster in Snail Host Conveys Resistance to Human Schistosome Parasites

Creator:: Tennessen, Jacob A., Théron, André, Marine, Melanie, Yeh, Jan-Ying, Rognon, Anne, and Blouin, Michael S.
Abstract:: Schistosomiasis, a neglected global pandemic, may be curtailed by blocking transmission of the parasite via its intermediate hosts, aquatic snails. Elucidating the genetic basis of snail-schistosome interaction is a key to this strategy. Here we map a natural parasite-resistance polymorphism from a Caribbean population of the snail Biomphalaria glabrata. In...
Resource Type:: Article
Full Text:: approximately 50% (53% +/- 4) to under 10% (3% +/- 2 for R10; 6% +/- 3 for R30) over five generations in the

Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish

Creator:: Evason, Kimberley J., Francisco, Macrina T., Juric, Vladislava, Balakrishnan, Sanjeev, del Pilar Lopez Pazmino, Maria, Gordan, John D., Kakar, Sanjay, Spitsbergen, Jan, Goga, Andrei, and Stainier, Didier Y. R.
Abstract:: Hepatocellular carcinoma (HCC) is one of the most lethal human cancers. The search for targeted treatments has been hampered by the lack of relevant animal models for the genetically diverse subsets of HCC, including the 20-40% of HCCs that are defined by activating mutations in the gene encoding β-catenin. To...
Resource Type:: Article
Full Text:: (G) or 4-month-old (H) zebrafish and human HCC showing architectural disruption with scattered

Spatiotemporal distribution of the anti-diabetic drug, metformin, in the lower Columbia River and its effect on phytoplankton growth

Creator:: Cummings, Brittany M.
Abstract:: Water quality impacts both human and ecosystem health. Many pharmaceuticals and personal care products are considered contaminants of emerging concern (CEC) due to their bioactive properties. Among these, metformin—the most commonly prescribed drug for treatment of type 2 diabetes—has been reported at high concentrations (μg L⁻¹) in stream, lake, and...
Resource Type:: Masters Thesis
Full Text:: . Sources and Sinks of Pharmaceutical CECs ..................................................... 4 1.2.3

Shades of Color at OAC, 1916-1921: The Untold Story of Palmer Patton

Creator:: Landis, Lawrence A.
Abstract:: Palmer Patton was a student of color at Oregon Agricultural College (OAC) from 1916-1920. He received bachelors and masters degrees in agriculture. He was African-American but identified as white. This presentation explores Patton's life before, during and after his years at OAC. This presentation was made at OSU's Lonnie B....
Resource Type:: Presentation
Full Text:: from Bay City. The asylum records indicate his birthplace as Canada. 4 Palmer Patton appears in

Displacement Patterns Between Children with and without Disabilities in an Inclusive Playgroup Setting

Creator:: Mayer, Tess Maureen
Abstract:: Purpose: The purposes of this study are to determine the within subject and between subject effects of play markings, gross motor toys, and a larger play space on the physical activity of children with and without disabilities. Method: A group comparison design was implemented and a total of 12 children...
Resource Type:: Honors College Thesis
Full Text:: than children with disabilities; (4) During the B phase (intervention), children without disabilities

Proteolytic Systems in Milk: Perspectives on the Evolutionary Function within the Mammary Gland and the Infant

Creator:: Dallas, David C., Murray, Niamh M., and Gan, Junai
Abstract:: Milk contains elements of numerous proteolytic systems (zymogens, active proteases, protease inhibitors and protease activators) produced in part from blood, in part by mammary epithelial cells and in part by immune cell secretion. Researchers have examined milk proteases for decades, as they can cause major defects in milk quality and...
Resource Type:: Article
Full Text:: /dialog/?doi=10.1007/s10911-015-9334-3&domain=pdf affect dairy product quality [3, 4]: overly high

The Effect of Novel Research Activities on Long-term Survival of Temporarily Captive Steller Sea Lions (Eumetopias jubatus)

Creator:: Shuert, Courtney, Horning, Markus, and Mellish, Jo-Ann
Abstract:: Two novel research approaches were developed to facilitate controlled access to, and long-term monitoring of, juvenile Steller sea lions for periods longer than typically afforded by traditional fieldwork. The Transient Juvenile Steller sea lion Project at the Alaska SeaLife Center facilitated nutritional, physiological, and behavioral studies on the platform of...
Resource Type:: Article
Full Text:: , 97365, United States of America,a, 4 North Pacific Research Board, Anchorage, AK, 99501, United States

Immunology beliefs as a factor in vaccine opposition among complementary and alternative medical providers

Creator:: Bean, Sandra J. and Catania, Joseph A.
Abstract:: Objectives: Parental pediatric vaccine decisions are influenced by parents' health provider networks. Complementary and alternative medical providers may be key influences in the networks of those parents who do not vaccinate their children. Methods: From March to July 2013, we conducted semi-structured interviews of Oregon complementary and alternative medical providers...
Resource Type:: Article
Full Text:: benefits for their children.4 Moreover, past research has shown that parental beliefs concerning the human

ScholarsArchive@OSU

Formation of Complexes at Plasmodesmata for Potyvirus Intercellular Movement Is Mediated by the Viral Protein P3N-PIPO

Novel Pactamycin Analogs Induce p53 Dependent Cell-Cycle Arrest at S-Phase in Human Head and Neck Squamous Cell Carcinoma (HNSCC) Cells

Hyperdiverse Gene Cluster in Snail Host Conveys Resistance to Human Schistosome Parasites

Identification of Chemical Inhibitors of β-Catenin-Driven Liver Tumorigenesis in Zebrafish

Spatiotemporal distribution of the anti-diabetic drug, metformin, in the lower Columbia River and its effect on phytoplankton growth

Shades of Color at OAC, 1916-1921: The Untold Story of Palmer Patton

Displacement Patterns Between Children with and without Disabilities in an Inclusive Playgroup Setting

Proteolytic Systems in Milk: Perspectives on the Evolutionary Function within the Mammary Gland and the Infant

The Effect of Novel Research Activities on Long-term Survival of Temporarily Captive Steller Sea Lions (Eumetopias jubatus)

Immunology beliefs as a factor in vaccine opposition among complementary and alternative medical providers

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